IFNA16

 

Full name: interferon alpha 16 Alias Symbol: IFN-alphaO
Type: protein-coding gene Cytoband: 9p21.3
Entrez ID: 3449 HGNC ID: HGNC:5421 Ensembl Gene: ENSG00000147885 OMIM ID: 147580
Drug and gene relationship at DGIdb

 

IFNA16 involved pathways:

KEGG pathway Description View
hsa04151PI3K-Akt signaling pathway
hsa04620Toll-like receptor signaling pathway
hsa04630Jak-STAT signaling pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05152Tuberculosis
hsa05160Hepatitis C
hsa05161Hepatitis B
hsa05162Measles

 

Expression of IFNA16:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IFNA16 3449 208448_x_at 0.0260 0.9312
GSE20347 IFNA16 3449 208448_x_at 0.0469 0.5654
GSE23400 IFNA16 3449 208448_x_at -0.1198 0.0005
GSE26886 IFNA16 3449 208448_x_at -0.0749 0.5022
GSE29001 IFNA16 3449 208448_x_at -0.1834 0.3265
GSE38129 IFNA16 3449 208448_x_at -0.0248 0.7348
GSE45670 IFNA16 3449 208448_x_at 0.0018 0.9866
GSE63941 IFNA16 3449 208448_x_at 0.0169 0.9167
GSE77861 IFNA16 3449 208448_x_at -0.0669 0.5209

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by IFNA16 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of IFNA16:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IFNA16 3449 2 17 11
GSE20123 IFNA16 3449 2 17 11
GSE43470 IFNA16 3449 4 13 26
GSE46452 IFNA16 3449 2 23 34
GSE47630 IFNA16 3449 3 27 10
GSE54993 IFNA16 3449 7 2 61
GSE54994 IFNA16 3449 8 16 29
GSE60625 IFNA16 3449 3 0 8
GSE74703 IFNA16 3449 4 10 22
GSE74704 IFNA16 3449 0 13 7
TCGA IFNA16 3449 11 53 32

Total number of gains: 46; Total number of losses: 191; Total Number of normals: 251.  

 

Somatic mutations of IFNA16:

 

Generating mutation plots.

 

Highly correlated genes for IFNA16:

 

Showing top 20/601 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IFNA16RUNX1T10.752275303
IFNA16CRYGC0.743864303
IFNA16CCIN0.74202303
IFNA16FGA0.729241303
IFNA16NMNAT20.705674303
IFNA16RAVER20.697678303
IFNA16LGALS130.695379404
IFNA16APAF10.68639303
IFNA16OXT0.685543303
IFNA16CCL250.683249303
IFNA16KIR2DS10.682945505
IFNA16ADAM220.680202404
IFNA16IL190.680119404
IFNA16GNG30.6786403
IFNA16RNF170.674271404
IFNA16C60.673335404
IFNA16NTNG10.672847403
IFNA16ATOH80.671982303
IFNA16PSG70.671789303
IFNA16MAGEA80.671607303

For details and further investigation, click here