IGFLR1

 

Full name: IGF like family receptor 1 Alias Symbol: FLJ22573
Type: protein-coding gene Cytoband: 19q13.12
Entrez ID: 79713 HGNC ID: HGNC:23620 Ensembl Gene: ENSG00000126246 OMIM ID: 614143
Drug and gene relationship at DGIdb

 

Expression of IGFLR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IGFLR1 79713 219690_at 0.4330 0.2880
GSE20347 IGFLR1 79713 219690_at 0.3872 0.0010
GSE23400 IGFLR1 79713 219690_at 0.2851 0.0000
GSE26886 IGFLR1 79713 219690_at 0.5081 0.0283
GSE29001 IGFLR1 79713 219690_at 0.2815 0.2206
GSE38129 IGFLR1 79713 219690_at 0.4490 0.0013
GSE45670 IGFLR1 79713 219690_at 0.2363 0.1634
GSE53622 IGFLR1 79713 59405 0.2669 0.0171
GSE53624 IGFLR1 79713 59405 0.6272 0.0000
GSE63941 IGFLR1 79713 219690_at 0.6188 0.2940
GSE77861 IGFLR1 79713 219690_at 0.1877 0.3569
GSE97050 IGFLR1 79713 A_23_P142424 0.7120 0.2251
SRP007169 IGFLR1 79713 RNAseq 0.9213 0.1951
SRP064894 IGFLR1 79713 RNAseq 1.2969 0.0003
SRP133303 IGFLR1 79713 RNAseq 0.1614 0.5281
SRP159526 IGFLR1 79713 RNAseq 0.0527 0.9130
SRP193095 IGFLR1 79713 RNAseq 0.1777 0.4094
SRP219564 IGFLR1 79713 RNAseq 1.2079 0.0085

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by IGFLR1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of IGFLR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IGFLR1 79713 7 4 19
GSE20123 IGFLR1 79713 7 3 20
GSE43470 IGFLR1 79713 3 7 33
GSE46452 IGFLR1 79713 48 1 10
GSE47630 IGFLR1 79713 9 5 26
GSE54993 IGFLR1 79713 17 3 50
GSE54994 IGFLR1 79713 7 9 37
GSE60625 IGFLR1 79713 9 0 2
GSE74703 IGFLR1 79713 3 4 29
GSE74704 IGFLR1 79713 6 1 13
TCGA IGFLR1 79713 22 10 64

Total number of gains: 138; Total number of losses: 47; Total Number of normals: 303.  

 

Somatic mutations of IGFLR1:

 

Generating mutation plots.

 

Highly correlated genes for IGFLR1:

 

Showing top 20/431 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IGFLR1CD280.753476404
IGFLR1FERMT30.749539403
IGFLR1CD300LF0.7401505
IGFLR1ZNF3410.709953303
IGFLR1TBXAS10.708892505
IGFLR1AKNA0.706636605
IGFLR1TNFSF13B0.694649605
IGFLR1ARVCF0.69445303
IGFLR1PIK3R50.691742404
IGFLR1TYROBP0.689981909
IGFLR1CFP0.688601303
IGFLR1PRSS530.686728303
IGFLR1ZBTB320.685591404
IGFLR1CD530.682584606
IGFLR1RENBP0.678309504
IGFLR1PSMB90.6751141009
IGFLR1TIMD40.67028303
IGFLR1C4orf460.664162303
IGFLR1PSMB8-AS10.663527505
IGFLR1THAP30.660652303

For details and further investigation, click here