| Full name: fermitin family member 3 | Alias Symbol: URP2|KIND3|MIG2B|MGC10966|MIG-2|UNC112C | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 83706 | HGNC ID: HGNC:23151 | Ensembl Gene: ENSG00000149781 | OMIM ID: 607901 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
FERMT3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04611 | Platelet activation |
Expression of FERMT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FERMT3 | 83706 | 223303_at | 0.4622 | 0.5477 | |
| GSE26886 | FERMT3 | 83706 | 223303_at | 0.3617 | 0.1194 | |
| GSE45670 | FERMT3 | 83706 | 223303_at | 0.1788 | 0.4464 | |
| GSE53622 | FERMT3 | 83706 | 55463 | -0.3373 | 0.0008 | |
| GSE53624 | FERMT3 | 83706 | 55463 | -0.6633 | 0.0000 | |
| GSE63941 | FERMT3 | 83706 | 223303_at | 0.2243 | 0.3511 | |
| GSE77861 | FERMT3 | 83706 | 223303_at | 0.0202 | 0.8997 | |
| GSE97050 | FERMT3 | 83706 | A_23_P64044 | 0.6521 | 0.1992 | |
| SRP007169 | FERMT3 | 83706 | RNAseq | 1.7891 | 0.0398 | |
| SRP008496 | FERMT3 | 83706 | RNAseq | 0.8605 | 0.1354 | |
| SRP064894 | FERMT3 | 83706 | RNAseq | 1.0550 | 0.0004 | |
| SRP133303 | FERMT3 | 83706 | RNAseq | 0.3083 | 0.1254 | |
| SRP159526 | FERMT3 | 83706 | RNAseq | -0.0953 | 0.8741 | |
| SRP193095 | FERMT3 | 83706 | RNAseq | 0.2316 | 0.3943 | |
| SRP219564 | FERMT3 | 83706 | RNAseq | 0.7536 | 0.1381 | |
| TCGA | FERMT3 | 83706 | RNAseq | -0.0994 | 0.4405 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FERMT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FERMT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FERMT3 | 83706 | 6 | 5 | 19 | |
| GSE20123 | FERMT3 | 83706 | 6 | 5 | 19 | |
| GSE43470 | FERMT3 | 83706 | 1 | 3 | 39 | |
| GSE46452 | FERMT3 | 83706 | 8 | 4 | 47 | |
| GSE47630 | FERMT3 | 83706 | 3 | 7 | 30 | |
| GSE54993 | FERMT3 | 83706 | 3 | 0 | 67 | |
| GSE54994 | FERMT3 | 83706 | 5 | 5 | 43 | |
| GSE60625 | FERMT3 | 83706 | 0 | 4 | 7 | |
| GSE74703 | FERMT3 | 83706 | 1 | 1 | 34 | |
| GSE74704 | FERMT3 | 83706 | 4 | 3 | 13 | |
| TCGA | FERMT3 | 83706 | 19 | 10 | 67 |
Total number of gains: 56; Total number of losses: 47; Total Number of normals: 385.
Somatic mutations of FERMT3:
Generating mutation plots.
Highly correlated genes for FERMT3:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FERMT3 | IGFLR1 | 0.749539 | 4 | 0 | 3 |
| FERMT3 | ST3GAL1 | 0.725331 | 3 | 0 | 3 |
| FERMT3 | LPXN | 0.723659 | 3 | 0 | 3 |
| FERMT3 | TCF7 | 0.723511 | 3 | 0 | 3 |
| FERMT3 | MYBBP1A | 0.707897 | 3 | 0 | 3 |
| FERMT3 | KMO | 0.702359 | 3 | 0 | 3 |
| FERMT3 | TPST2 | 0.698699 | 3 | 0 | 3 |
| FERMT3 | ADCK5 | 0.692088 | 3 | 0 | 3 |
| FERMT3 | APOL2 | 0.686935 | 3 | 0 | 3 |
| FERMT3 | ITGAX | 0.686322 | 4 | 0 | 3 |
| FERMT3 | LY86 | 0.685689 | 4 | 0 | 3 |
| FERMT3 | FGR | 0.685028 | 4 | 0 | 3 |
| FERMT3 | BATF | 0.684865 | 4 | 0 | 4 |
| FERMT3 | KLHDC7B | 0.684702 | 4 | 0 | 4 |
| FERMT3 | PAX5 | 0.683921 | 4 | 0 | 4 |
| FERMT3 | HLA-DMB | 0.679218 | 3 | 0 | 3 |
| FERMT3 | PTGER1 | 0.678171 | 3 | 0 | 3 |
| FERMT3 | NCF4 | 0.671617 | 5 | 0 | 4 |
| FERMT3 | WDFY4 | 0.669911 | 4 | 0 | 3 |
| FERMT3 | MAST3 | 0.663841 | 4 | 0 | 4 |
For details and further investigation, click here
