PSMB9

 

Full name: proteasome subunit beta 9 Alias Symbol: RING12|beta1i|PSMB6i
Type: protein-coding gene Cytoband: 6p21.32
Entrez ID: 5698 HGNC ID: HGNC:9546 Ensembl Gene: ENSG00000240065 OMIM ID: 177045
Drug and gene relationship at DGIdb

 

Expression of PSMB9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMB9 5698 204279_at 1.1738 0.1553
GSE20347 PSMB9 5698 204279_at 1.0416 0.0025
GSE23400 PSMB9 5698 204279_at 1.1900 0.0000
GSE26886 PSMB9 5698 204279_at 0.4506 0.4055
GSE29001 PSMB9 5698 204279_at 1.7450 0.0002
GSE38129 PSMB9 5698 204279_at 0.9490 0.0009
GSE45670 PSMB9 5698 204279_at 1.3251 0.0039
GSE53622 PSMB9 5698 164943 0.3733 0.0000
GSE53624 PSMB9 5698 164943 0.4546 0.0000
GSE63941 PSMB9 5698 204279_at 0.1347 0.9332
GSE77861 PSMB9 5698 204279_at 0.3431 0.5099
GSE97050 PSMB9 5698 A_23_P111000 0.3761 0.2484
SRP007169 PSMB9 5698 RNAseq 1.7360 0.0156
SRP008496 PSMB9 5698 RNAseq 1.1211 0.0287
SRP064894 PSMB9 5698 RNAseq 1.1802 0.0001
SRP133303 PSMB9 5698 RNAseq 1.1499 0.0001
SRP159526 PSMB9 5698 RNAseq 0.5974 0.3789
SRP193095 PSMB9 5698 RNAseq 0.6488 0.0058
SRP219564 PSMB9 5698 RNAseq 2.3818 0.0003
TCGA PSMB9 5698 RNAseq 0.6270 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by PSMB9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSMB9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMB9 5698 5 0 25
GSE20123 PSMB9 5698 5 0 25
GSE43470 PSMB9 5698 5 1 37
GSE46452 PSMB9 5698 2 9 48
GSE47630 PSMB9 5698 8 4 28
GSE54993 PSMB9 5698 3 1 66
GSE54994 PSMB9 5698 11 4 38
GSE60625 PSMB9 5698 1 0 10
GSE74703 PSMB9 5698 5 0 31
GSE74704 PSMB9 5698 2 0 18
TCGA PSMB9 5698 16 16 64

Total number of gains: 63; Total number of losses: 35; Total Number of normals: 390.  

 

Somatic mutations of PSMB9:

 

Generating mutation plots.

 

Highly correlated genes for PSMB9:

 

Showing top 20/398 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMB9PSMB80.8278312012
PSMB9TAP10.80768710010
PSMB9HLA-F0.78870212011
PSMB9UBE2L60.78869813013
PSMB9HLA-B0.78227613013
PSMB9BTN3A30.76465410010
PSMB9HLA-A0.76149212011
PSMB9HLA-C0.7573413013
PSMB9IFI350.73528912011
PSMB9RTP40.70337312012
PSMB9MAST30.695987303
PSMB9GNLY0.69596611011
PSMB9GBP50.693263606
PSMB9IFITM10.691925909
PSMB9PSMB100.69007412010
PSMB9HLA-G0.6874891109
PSMB9BATF20.686629605
PSMB9RNF2130.685991404
PSMB9DDX600.68567612012
PSMB9DTX3L0.685418807

For details and further investigation, click here