| Full name: T cell immunoglobulin and mucin domain containing 4 | Alias Symbol: TIM4 | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 91937 | HGNC ID: HGNC:25132 | Ensembl Gene: ENSG00000145850 | OMIM ID: 610096 |
| Drug and gene relationship at DGIdb | |||
Expression of TIMD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIMD4 | 91937 | 1552280_at | -0.1181 | 0.8746 | |
| GSE26886 | TIMD4 | 91937 | 1552280_at | -0.0907 | 0.3617 | |
| GSE45670 | TIMD4 | 91937 | 1552280_at | 0.0143 | 0.9186 | |
| GSE53622 | TIMD4 | 91937 | 45470 | -0.2305 | 0.0249 | |
| GSE53624 | TIMD4 | 91937 | 51723 | -0.1282 | 0.3122 | |
| GSE63941 | TIMD4 | 91937 | 1552280_at | -0.0055 | 0.9757 | |
| GSE77861 | TIMD4 | 91937 | 1552280_at | -0.0046 | 0.9729 | |
| GSE97050 | TIMD4 | 91937 | A_33_P3236020 | 0.5530 | 0.2151 | |
| TCGA | TIMD4 | 91937 | RNAseq | -0.9793 | 0.3719 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TIMD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIMD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIMD4 | 91937 | 0 | 11 | 19 | |
| GSE20123 | TIMD4 | 91937 | 0 | 11 | 19 | |
| GSE43470 | TIMD4 | 91937 | 2 | 10 | 31 | |
| GSE46452 | TIMD4 | 91937 | 0 | 27 | 32 | |
| GSE47630 | TIMD4 | 91937 | 0 | 20 | 20 | |
| GSE54993 | TIMD4 | 91937 | 9 | 1 | 60 | |
| GSE54994 | TIMD4 | 91937 | 1 | 17 | 35 | |
| GSE60625 | TIMD4 | 91937 | 0 | 0 | 11 | |
| GSE74703 | TIMD4 | 91937 | 2 | 8 | 26 | |
| GSE74704 | TIMD4 | 91937 | 0 | 6 | 14 | |
| TCGA | TIMD4 | 91937 | 4 | 36 | 56 |
Total number of gains: 18; Total number of losses: 147; Total Number of normals: 323.
Somatic mutations of TIMD4:
Generating mutation plots.
Highly correlated genes for TIMD4:
Showing top 20/67 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIMD4 | MEI1 | 0.680966 | 4 | 0 | 4 |
| TIMD4 | IGFLR1 | 0.67028 | 3 | 0 | 3 |
| TIMD4 | PLD4 | 0.669423 | 3 | 0 | 3 |
| TIMD4 | UBQLN3 | 0.666958 | 3 | 0 | 3 |
| TIMD4 | MZB1 | 0.659707 | 4 | 0 | 3 |
| TIMD4 | EMID1 | 0.651244 | 3 | 0 | 3 |
| TIMD4 | TLR10 | 0.639691 | 3 | 0 | 3 |
| TIMD4 | FRMPD1 | 0.636022 | 3 | 0 | 3 |
| TIMD4 | CHRM5 | 0.634507 | 3 | 0 | 3 |
| TIMD4 | CPSF1 | 0.633066 | 3 | 0 | 3 |
| TIMD4 | CD37 | 0.62893 | 3 | 0 | 3 |
| TIMD4 | TSPO2 | 0.612716 | 5 | 0 | 3 |
| TIMD4 | KIR2DL5A | 0.612558 | 4 | 0 | 3 |
| TIMD4 | CD28 | 0.61039 | 4 | 0 | 3 |
| TIMD4 | BLK | 0.610059 | 3 | 0 | 3 |
| TIMD4 | CR1 | 0.609702 | 3 | 0 | 3 |
| TIMD4 | DOCK2 | 0.60965 | 5 | 0 | 4 |
| TIMD4 | PNPLA5 | 0.607605 | 3 | 0 | 3 |
| TIMD4 | CD48 | 0.607182 | 5 | 0 | 4 |
| TIMD4 | C12orf42 | 0.603703 | 4 | 0 | 4 |
For details and further investigation, click here
