| Full name: AT-hook transcription factor | Alias Symbol: KIAA1968 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 80709 | HGNC ID: HGNC:24108 | Ensembl Gene: ENSG00000106948 | OMIM ID: 605729 |
| Drug and gene relationship at DGIdb | |||
Expression of AKNA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKNA | 80709 | 225701_at | 0.2776 | 0.7870 | |
| GSE26886 | AKNA | 80709 | 225701_at | 0.6298 | 0.0058 | |
| GSE45670 | AKNA | 80709 | 225701_at | -0.1733 | 0.4179 | |
| GSE53622 | AKNA | 80709 | 65880 | -0.1879 | 0.0062 | |
| GSE53624 | AKNA | 80709 | 65880 | -0.2490 | 0.0000 | |
| GSE63941 | AKNA | 80709 | 225701_at | -0.1418 | 0.8630 | |
| GSE77861 | AKNA | 80709 | 225701_at | 0.0705 | 0.7032 | |
| GSE97050 | AKNA | 80709 | A_33_P3220047 | 0.4283 | 0.2434 | |
| SRP007169 | AKNA | 80709 | RNAseq | 1.0607 | 0.0459 | |
| SRP008496 | AKNA | 80709 | RNAseq | 0.9555 | 0.0224 | |
| SRP064894 | AKNA | 80709 | RNAseq | 0.0638 | 0.7838 | |
| SRP133303 | AKNA | 80709 | RNAseq | -0.5527 | 0.0025 | |
| SRP159526 | AKNA | 80709 | RNAseq | -1.0409 | 0.0609 | |
| SRP193095 | AKNA | 80709 | RNAseq | -0.2476 | 0.2290 | |
| SRP219564 | AKNA | 80709 | RNAseq | 0.1503 | 0.6469 | |
| TCGA | AKNA | 80709 | RNAseq | -0.2820 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AKNA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKNA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKNA | 80709 | 3 | 10 | 17 | |
| GSE20123 | AKNA | 80709 | 3 | 11 | 16 | |
| GSE43470 | AKNA | 80709 | 5 | 3 | 35 | |
| GSE46452 | AKNA | 80709 | 6 | 13 | 40 | |
| GSE47630 | AKNA | 80709 | 3 | 16 | 21 | |
| GSE54993 | AKNA | 80709 | 3 | 3 | 64 | |
| GSE54994 | AKNA | 80709 | 9 | 10 | 34 | |
| GSE60625 | AKNA | 80709 | 0 | 0 | 11 | |
| GSE74703 | AKNA | 80709 | 4 | 3 | 29 | |
| GSE74704 | AKNA | 80709 | 2 | 7 | 11 | |
| TCGA | AKNA | 80709 | 27 | 21 | 48 |
Total number of gains: 65; Total number of losses: 97; Total Number of normals: 326.
Somatic mutations of AKNA:
Generating mutation plots.
Highly correlated genes for AKNA:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKNA | TBC1D10C | 0.774522 | 5 | 0 | 5 |
| AKNA | APBB1IP | 0.771455 | 4 | 0 | 4 |
| AKNA | CD53 | 0.758728 | 3 | 0 | 3 |
| AKNA | DOCK2 | 0.751303 | 6 | 0 | 6 |
| AKNA | PPP1R16B | 0.747194 | 3 | 0 | 3 |
| AKNA | FAM78A | 0.734478 | 4 | 0 | 3 |
| AKNA | TRAT1 | 0.7321 | 4 | 0 | 4 |
| AKNA | CD3G | 0.724071 | 4 | 0 | 4 |
| AKNA | SLC12A7 | 0.717716 | 3 | 0 | 3 |
| AKNA | TNFRSF1B | 0.715362 | 5 | 0 | 5 |
| AKNA | CTLA4 | 0.709406 | 3 | 0 | 3 |
| AKNA | WAS | 0.708156 | 7 | 0 | 7 |
| AKNA | IGFLR1 | 0.706636 | 6 | 0 | 5 |
| AKNA | CYTIP | 0.705585 | 5 | 0 | 4 |
| AKNA | CD2 | 0.703592 | 4 | 0 | 4 |
| AKNA | BATF2 | 0.701066 | 3 | 0 | 3 |
| AKNA | PTPRCAP | 0.698969 | 5 | 0 | 4 |
| AKNA | TNFSF13B | 0.693389 | 6 | 0 | 5 |
| AKNA | CD48 | 0.686855 | 6 | 0 | 5 |
| AKNA | ALDH16A1 | 0.686474 | 4 | 0 | 4 |
For details and further investigation, click here
