| Full name: interleukin 1 receptor like 1 | Alias Symbol: ST2|FIT-1|ST2L|ST2V|DER4|T1|IL33R | ||
| Type: protein-coding gene | Cytoband: 2q12.1 | ||
| Entrez ID: 9173 | HGNC ID: HGNC:5998 | Ensembl Gene: ENSG00000115602 | OMIM ID: 601203 |
| Drug and gene relationship at DGIdb | |||
Expression of IL1RL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL1RL1 | 9173 | 210442_at | 0.0428 | 0.9011 | |
| GSE20347 | IL1RL1 | 9173 | 210442_at | -0.0523 | 0.6220 | |
| GSE23400 | IL1RL1 | 9173 | 210442_at | -0.2221 | 0.0000 | |
| GSE26886 | IL1RL1 | 9173 | 210442_at | -0.2146 | 0.1043 | |
| GSE29001 | IL1RL1 | 9173 | 207526_s_at | 0.6604 | 0.1509 | |
| GSE38129 | IL1RL1 | 9173 | 210442_at | -0.1030 | 0.2799 | |
| GSE45670 | IL1RL1 | 9173 | 242809_at | -0.2998 | 0.0964 | |
| GSE53622 | IL1RL1 | 9173 | 11324 | -0.7395 | 0.0016 | |
| GSE53624 | IL1RL1 | 9173 | 11324 | -0.3297 | 0.1237 | |
| GSE63941 | IL1RL1 | 9173 | 242809_at | 0.1228 | 0.6545 | |
| GSE77861 | IL1RL1 | 9173 | 242809_at | -0.0004 | 0.9976 | |
| GSE97050 | IL1RL1 | 9173 | A_23_P51126 | -0.1278 | 0.6693 | |
| SRP007169 | IL1RL1 | 9173 | RNAseq | 0.8320 | 0.2049 | |
| SRP064894 | IL1RL1 | 9173 | RNAseq | -0.1320 | 0.7834 | |
| SRP133303 | IL1RL1 | 9173 | RNAseq | -0.9720 | 0.0017 | |
| SRP159526 | IL1RL1 | 9173 | RNAseq | 0.4998 | 0.5520 | |
| SRP193095 | IL1RL1 | 9173 | RNAseq | 0.4833 | 0.0604 | |
| SRP219564 | IL1RL1 | 9173 | RNAseq | -0.2615 | 0.6277 | |
| TCGA | IL1RL1 | 9173 | RNAseq | -1.3548 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IL1RL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL1RL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL1RL1 | 9173 | 5 | 2 | 23 | |
| GSE20123 | IL1RL1 | 9173 | 5 | 2 | 23 | |
| GSE43470 | IL1RL1 | 9173 | 4 | 1 | 38 | |
| GSE46452 | IL1RL1 | 9173 | 1 | 4 | 54 | |
| GSE47630 | IL1RL1 | 9173 | 7 | 0 | 33 | |
| GSE54993 | IL1RL1 | 9173 | 0 | 6 | 64 | |
| GSE54994 | IL1RL1 | 9173 | 11 | 0 | 42 | |
| GSE60625 | IL1RL1 | 9173 | 0 | 3 | 8 | |
| GSE74703 | IL1RL1 | 9173 | 4 | 1 | 31 | |
| GSE74704 | IL1RL1 | 9173 | 3 | 1 | 16 | |
| TCGA | IL1RL1 | 9173 | 35 | 5 | 56 |
Total number of gains: 75; Total number of losses: 25; Total Number of normals: 388.
Somatic mutations of IL1RL1:
Generating mutation plots.
Highly correlated genes for IL1RL1:
Showing top 20/568 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL1RL1 | PRL | 0.773743 | 4 | 0 | 4 |
| IL1RL1 | DCC | 0.769151 | 4 | 0 | 4 |
| IL1RL1 | GGN | 0.726868 | 3 | 0 | 3 |
| IL1RL1 | PHLDB1 | 0.722237 | 5 | 0 | 5 |
| IL1RL1 | C22orf31 | 0.721497 | 5 | 0 | 5 |
| IL1RL1 | MUC5AC | 0.713073 | 3 | 0 | 3 |
| IL1RL1 | CBL | 0.710784 | 4 | 0 | 4 |
| IL1RL1 | PPP3CC | 0.710473 | 3 | 0 | 3 |
| IL1RL1 | NPHS2 | 0.705705 | 4 | 0 | 4 |
| IL1RL1 | FAM167B | 0.704827 | 3 | 0 | 3 |
| IL1RL1 | TPBGL | 0.691458 | 3 | 0 | 3 |
| IL1RL1 | RNF185-AS1 | 0.689788 | 4 | 0 | 4 |
| IL1RL1 | SLC28A2 | 0.688026 | 5 | 0 | 4 |
| IL1RL1 | ADAM22 | 0.687429 | 4 | 0 | 4 |
| IL1RL1 | CHN2 | 0.686934 | 3 | 0 | 3 |
| IL1RL1 | SCNN1G | 0.686566 | 3 | 0 | 3 |
| IL1RL1 | E2F4 | 0.683848 | 6 | 0 | 6 |
| IL1RL1 | NUCB1 | 0.680464 | 3 | 0 | 3 |
| IL1RL1 | DISC1 | 0.679664 | 5 | 0 | 5 |
| IL1RL1 | TIRAP | 0.677534 | 3 | 0 | 3 |
For details and further investigation, click here
