| Full name: interleukin 37 | Alias Symbol: FIL1|FIL1Z|FIL1(ZETA)|IL-1H4|IL-1RP1|IL-1F7 | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 27178 | HGNC ID: HGNC:15563 | Ensembl Gene: ENSG00000125571 | OMIM ID: 605510 |
| Drug and gene relationship at DGIdb | |||
Expression of IL37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL37 | 27178 | 224555_x_at | 0.0504 | 0.8651 | |
| GSE20347 | IL37 | 27178 | 221470_s_at | 0.1148 | 0.0387 | |
| GSE23400 | IL37 | 27178 | 221470_s_at | -0.0081 | 0.7811 | |
| GSE26886 | IL37 | 27178 | 224555_x_at | -0.2164 | 0.0380 | |
| GSE29001 | IL37 | 27178 | 221470_s_at | -0.0086 | 0.9334 | |
| GSE38129 | IL37 | 27178 | 221470_s_at | 0.0509 | 0.3384 | |
| GSE45670 | IL37 | 27178 | 224555_x_at | -0.0155 | 0.8938 | |
| GSE53622 | IL37 | 27178 | 124368 | -0.4821 | 0.0000 | |
| GSE53624 | IL37 | 27178 | 124368 | -1.5160 | 0.0000 | |
| GSE63941 | IL37 | 27178 | 224555_x_at | 0.1836 | 0.3328 | |
| GSE77861 | IL37 | 27178 | 224555_x_at | -0.0129 | 0.9450 | |
| GSE97050 | IL37 | 27178 | A_23_P5654 | -0.2754 | 0.3038 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IL37 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of IL37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL37 | 27178 | 6 | 2 | 22 | |
| GSE20123 | IL37 | 27178 | 6 | 2 | 22 | |
| GSE43470 | IL37 | 27178 | 3 | 1 | 39 | |
| GSE46452 | IL37 | 27178 | 1 | 4 | 54 | |
| GSE47630 | IL37 | 27178 | 7 | 0 | 33 | |
| GSE54993 | IL37 | 27178 | 0 | 6 | 64 | |
| GSE54994 | IL37 | 27178 | 10 | 0 | 43 | |
| GSE60625 | IL37 | 27178 | 0 | 3 | 8 | |
| GSE74703 | IL37 | 27178 | 3 | 1 | 32 | |
| GSE74704 | IL37 | 27178 | 3 | 2 | 15 | |
| TCGA | IL37 | 27178 | 31 | 6 | 59 |
Total number of gains: 70; Total number of losses: 27; Total Number of normals: 391.
Somatic mutations of IL37:
Generating mutation plots.
Highly correlated genes for IL37:
Showing top 20/178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL37 | RNF222 | 0.800501 | 3 | 0 | 3 |
| IL37 | KRTAP5-4 | 0.767548 | 3 | 0 | 3 |
| IL37 | KRTAP5-11 | 0.752426 | 3 | 0 | 3 |
| IL37 | NOTO | 0.742801 | 3 | 0 | 3 |
| IL37 | GPR62 | 0.742194 | 4 | 0 | 4 |
| IL37 | KRTAP10-8 | 0.7288 | 3 | 0 | 3 |
| IL37 | CCER1 | 0.714655 | 3 | 0 | 3 |
| IL37 | SLC5A8 | 0.66064 | 3 | 0 | 3 |
| IL37 | HMGB4 | 0.650173 | 3 | 0 | 3 |
| IL37 | METRNL | 0.649802 | 3 | 0 | 3 |
| IL37 | IGSF22 | 0.648328 | 3 | 0 | 3 |
| IL37 | DNAI2 | 0.640932 | 6 | 0 | 3 |
| IL37 | CYSRT1 | 0.636836 | 3 | 0 | 3 |
| IL37 | SPRR1A | 0.635835 | 3 | 0 | 3 |
| IL37 | CDKL2 | 0.631304 | 3 | 0 | 3 |
| IL37 | CYP11A1 | 0.629122 | 4 | 0 | 3 |
| IL37 | DGCR12 | 0.625558 | 3 | 0 | 3 |
| IL37 | XG | 0.624257 | 3 | 0 | 3 |
| IL37 | GPHB5 | 0.622993 | 5 | 0 | 4 |
| IL37 | CST9 | 0.621982 | 4 | 0 | 3 |
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