| Full name: popeye domain containing 2 | Alias Symbol: POP2 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 64091 | HGNC ID: HGNC:17648 | Ensembl Gene: ENSG00000121577 | OMIM ID: 605823 |
| Drug and gene relationship at DGIdb | |||
Expression of POPDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POPDC2 | 64091 | 219647_at | -0.5716 | 0.7367 | |
| GSE20347 | POPDC2 | 64091 | 219647_at | 0.0009 | 0.9963 | |
| GSE23400 | POPDC2 | 64091 | 219647_at | -0.0420 | 0.4562 | |
| GSE26886 | POPDC2 | 64091 | 219647_at | 0.2273 | 0.0130 | |
| GSE29001 | POPDC2 | 64091 | 219647_at | -0.0152 | 0.9277 | |
| GSE38129 | POPDC2 | 64091 | 219647_at | -0.5570 | 0.0570 | |
| GSE45670 | POPDC2 | 64091 | 219647_at | -0.1497 | 0.3624 | |
| GSE53622 | POPDC2 | 64091 | 68172 | -0.1592 | 0.4352 | |
| GSE53624 | POPDC2 | 64091 | 38932 | 0.2825 | 0.0019 | |
| GSE63941 | POPDC2 | 64091 | 219647_at | -0.1420 | 0.2737 | |
| GSE77861 | POPDC2 | 64091 | 219647_at | 0.0805 | 0.4471 | |
| GSE97050 | POPDC2 | 64091 | A_24_P257336 | -0.8503 | 0.1703 | |
| SRP064894 | POPDC2 | 64091 | RNAseq | 1.3559 | 0.0000 | |
| SRP133303 | POPDC2 | 64091 | RNAseq | -0.6139 | 0.0326 | |
| SRP159526 | POPDC2 | 64091 | RNAseq | 0.0330 | 0.9337 | |
| SRP219564 | POPDC2 | 64091 | RNAseq | 0.1150 | 0.9063 | |
| TCGA | POPDC2 | 64091 | RNAseq | -0.7001 | 0.0043 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POPDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POPDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POPDC2 | 64091 | 18 | 0 | 12 | |
| GSE20123 | POPDC2 | 64091 | 18 | 0 | 12 | |
| GSE43470 | POPDC2 | 64091 | 21 | 1 | 21 | |
| GSE46452 | POPDC2 | 64091 | 14 | 5 | 40 | |
| GSE47630 | POPDC2 | 64091 | 16 | 5 | 19 | |
| GSE54993 | POPDC2 | 64091 | 2 | 6 | 62 | |
| GSE54994 | POPDC2 | 64091 | 30 | 4 | 19 | |
| GSE60625 | POPDC2 | 64091 | 0 | 6 | 5 | |
| GSE74703 | POPDC2 | 64091 | 17 | 1 | 18 | |
| GSE74704 | POPDC2 | 64091 | 13 | 0 | 7 | |
| TCGA | POPDC2 | 64091 | 53 | 7 | 36 |
Total number of gains: 202; Total number of losses: 35; Total Number of normals: 251.
Somatic mutations of POPDC2:
Generating mutation plots.
Highly correlated genes for POPDC2:
Showing top 20/699 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POPDC2 | KLHL41 | 0.823175 | 3 | 0 | 3 |
| POPDC2 | C20orf194 | 0.756928 | 3 | 0 | 3 |
| POPDC2 | FNDC5 | 0.754152 | 4 | 0 | 3 |
| POPDC2 | GPM6A | 0.742723 | 7 | 0 | 7 |
| POPDC2 | HOXA4 | 0.732451 | 4 | 0 | 4 |
| POPDC2 | DMPK | 0.730621 | 6 | 0 | 5 |
| POPDC2 | DNAJC27 | 0.729661 | 3 | 0 | 3 |
| POPDC2 | INPP4A | 0.728581 | 3 | 0 | 3 |
| POPDC2 | SMYD1 | 0.726262 | 4 | 0 | 4 |
| POPDC2 | SMPX | 0.720184 | 8 | 0 | 6 |
| POPDC2 | CACNA1C | 0.710248 | 6 | 0 | 6 |
| POPDC2 | PDZRN4 | 0.710144 | 7 | 0 | 6 |
| POPDC2 | RNF150 | 0.70888 | 3 | 0 | 3 |
| POPDC2 | ITIH6 | 0.706717 | 3 | 0 | 3 |
| POPDC2 | CASQ2 | 0.70668 | 6 | 0 | 5 |
| POPDC2 | NME5 | 0.705244 | 6 | 0 | 5 |
| POPDC2 | NCS1 | 0.702383 | 3 | 0 | 3 |
| POPDC2 | TECPR2 | 0.701729 | 5 | 0 | 4 |
| POPDC2 | PI16 | 0.701244 | 4 | 0 | 3 |
| POPDC2 | FOXN3 | 0.698435 | 4 | 0 | 4 |
For details and further investigation, click here
