INVS

 

Full name: inversin Alias Symbol: 
Type: protein-coding gene Cytoband: 9q31.1
Entrez ID: 27130 HGNC ID: HGNC:17870 Ensembl Gene: ENSG00000119509 OMIM ID: 243305
Drug and gene relationship at DGIdb

 

INVS involved pathways:

KEGG pathway Description View
hsa04310Wnt signaling pathway

 

Expression of INVS:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 INVS 27130 210114_at 0.0881 0.8020
GSE20347 INVS 27130 210114_at 0.1529 0.4321
GSE23400 INVS 27130 210114_at 0.2174 0.0004
GSE26886 INVS 27130 210114_at 1.3150 0.0000
GSE29001 INVS 27130 210114_at 0.3223 0.3862
GSE38129 INVS 27130 210114_at 0.2018 0.1797
GSE45670 INVS 27130 210114_at 0.6488 0.0001
GSE53622 INVS 27130 97086 0.2187 0.0015
GSE53624 INVS 27130 97086 0.4409 0.0000
GSE63941 INVS 27130 210114_at 0.1022 0.8342
GSE77861 INVS 27130 210114_at 0.2160 0.3033
GSE97050 INVS 27130 A_23_P157970 -0.4950 0.1658
SRP007169 INVS 27130 RNAseq 0.7899 0.0529
SRP008496 INVS 27130 RNAseq 0.7672 0.0051
SRP064894 INVS 27130 RNAseq 0.4623 0.0089
SRP133303 INVS 27130 RNAseq 0.0974 0.5563
SRP159526 INVS 27130 RNAseq 0.3689 0.1995
SRP193095 INVS 27130 RNAseq 0.3545 0.0006
SRP219564 INVS 27130 RNAseq 0.0153 0.9528
TCGA INVS 27130 RNAseq 0.0374 0.5968

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by INVS expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of INVS:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 INVS 27130 4 9 17
GSE20123 INVS 27130 5 9 16
GSE43470 INVS 27130 6 3 34
GSE46452 INVS 27130 6 13 40
GSE47630 INVS 27130 1 17 22
GSE54993 INVS 27130 3 3 64
GSE54994 INVS 27130 9 11 33
GSE60625 INVS 27130 0 0 11
GSE74703 INVS 27130 5 3 28
GSE74704 INVS 27130 2 6 12
TCGA INVS 27130 27 22 47

Total number of gains: 68; Total number of losses: 96; Total Number of normals: 324.  

 

Somatic mutations of INVS:

 

Generating mutation plots.

 

Highly correlated genes for INVS:

 

Showing top 20/487 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
INVSBIRC60.801665303
INVSTWIST20.785745303
INVSUSP400.770759303
INVSSDR39U10.769701303
INVSFAM168A0.766897303
INVSFAF20.732913505
INVSHERPUD20.724816303
INVSSERPINA30.723529303
INVSPPP6R30.72132303
INVSIDS0.71901303
INVSAMDHD10.716026303
INVSMTX30.707706303
INVSMB21D20.691699403
INVSCERCAM0.691113404
INVSTLK10.684199303
INVSSEMA3C0.68313303
INVSANKRD90.675839403
INVSNGF0.67118303
INVSSPIRE10.670453503
INVSPTGS20.667963303

For details and further investigation, click here