| Full name: interaction protein for cytohesin exchange factors 1 | Alias Symbol: PIP3-E|KIAA0403 | ||
| Type: protein-coding gene | Cytoband: 6q25.2 | ||
| Entrez ID: 26034 | HGNC ID: HGNC:21204 | Ensembl Gene: ENSG00000074706 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IPCEF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IPCEF1 | 26034 | 214735_at | -0.0322 | 0.9792 | |
| GSE20347 | IPCEF1 | 26034 | 214735_at | -0.5006 | 0.0010 | |
| GSE23400 | IPCEF1 | 26034 | 214735_at | -0.1809 | 0.0000 | |
| GSE26886 | IPCEF1 | 26034 | 214735_at | -0.9731 | 0.0229 | |
| GSE29001 | IPCEF1 | 26034 | 214735_at | -0.8889 | 0.0109 | |
| GSE38129 | IPCEF1 | 26034 | 214735_at | -0.5684 | 0.0004 | |
| GSE45670 | IPCEF1 | 26034 | 214735_at | -0.3104 | 0.1166 | |
| GSE53622 | IPCEF1 | 26034 | 43610 | -0.8510 | 0.0000 | |
| GSE53624 | IPCEF1 | 26034 | 43610 | -0.8307 | 0.0000 | |
| GSE63941 | IPCEF1 | 26034 | 214735_at | 0.4823 | 0.4706 | |
| GSE77861 | IPCEF1 | 26034 | 214735_at | -0.2070 | 0.1214 | |
| GSE97050 | IPCEF1 | 26034 | A_33_P3397995 | 0.0860 | 0.7248 | |
| SRP007169 | IPCEF1 | 26034 | RNAseq | -0.7247 | 0.3433 | |
| SRP064894 | IPCEF1 | 26034 | RNAseq | -1.0359 | 0.0009 | |
| SRP133303 | IPCEF1 | 26034 | RNAseq | -0.9556 | 0.0000 | |
| SRP159526 | IPCEF1 | 26034 | RNAseq | -1.7205 | 0.0100 | |
| SRP193095 | IPCEF1 | 26034 | RNAseq | -1.0371 | 0.0000 | |
| SRP219564 | IPCEF1 | 26034 | RNAseq | -0.2858 | 0.6113 | |
| TCGA | IPCEF1 | 26034 | RNAseq | -0.3333 | 0.0962 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by IPCEF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IPCEF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IPCEF1 | 26034 | 1 | 4 | 25 | |
| GSE20123 | IPCEF1 | 26034 | 1 | 3 | 26 | |
| GSE43470 | IPCEF1 | 26034 | 4 | 0 | 39 | |
| GSE46452 | IPCEF1 | 26034 | 3 | 10 | 46 | |
| GSE47630 | IPCEF1 | 26034 | 9 | 4 | 27 | |
| GSE54993 | IPCEF1 | 26034 | 3 | 2 | 65 | |
| GSE54994 | IPCEF1 | 26034 | 8 | 8 | 37 | |
| GSE60625 | IPCEF1 | 26034 | 0 | 1 | 10 | |
| GSE74703 | IPCEF1 | 26034 | 4 | 0 | 32 | |
| GSE74704 | IPCEF1 | 26034 | 0 | 1 | 19 | |
| TCGA | IPCEF1 | 26034 | 12 | 21 | 63 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of IPCEF1:
Generating mutation plots.
Highly correlated genes for IPCEF1:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IPCEF1 | BTLA | 0.682051 | 4 | 0 | 3 |
| IPCEF1 | LIPM | 0.674842 | 3 | 0 | 3 |
| IPCEF1 | ARHGAP9 | 0.649776 | 4 | 0 | 4 |
| IPCEF1 | KLRB1 | 0.631713 | 10 | 0 | 9 |
| IPCEF1 | GIMAP6 | 0.628516 | 5 | 0 | 5 |
| IPCEF1 | SLAMF7 | 0.624675 | 5 | 0 | 4 |
| IPCEF1 | ITK | 0.617854 | 7 | 0 | 5 |
| IPCEF1 | DOCK8 | 0.616579 | 4 | 0 | 4 |
| IPCEF1 | GIMAP7 | 0.615447 | 5 | 0 | 4 |
| IPCEF1 | NLRC3 | 0.615339 | 7 | 0 | 5 |
| IPCEF1 | C1orf162 | 0.613199 | 3 | 0 | 3 |
| IPCEF1 | LRMP | 0.611799 | 11 | 0 | 10 |
| IPCEF1 | UBASH3A | 0.60748 | 8 | 0 | 7 |
| IPCEF1 | THEMIS | 0.606676 | 6 | 0 | 5 |
| IPCEF1 | SUDS3 | 0.605646 | 3 | 0 | 3 |
| IPCEF1 | CCDC160 | 0.603735 | 3 | 0 | 3 |
| IPCEF1 | CD247 | 0.603289 | 9 | 0 | 8 |
| IPCEF1 | ZNF831 | 0.602359 | 7 | 0 | 4 |
| IPCEF1 | INPP5D | 0.600573 | 10 | 0 | 8 |
| IPCEF1 | GAPT | 0.598312 | 5 | 0 | 4 |
For details and further investigation, click here
