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File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
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Function: require_once

Multi-Omics Database of ESCC

 

UBASH3A

 

Full name: ubiquitin associated and SH3 domain containing A Alias Symbol: STS-2|TULA|CLIP4
Type: protein-coding gene Cytoband: 21q22.3
Entrez ID: 53347 HGNC ID: HGNC:12462 Ensembl Gene: ENSG00000160185 OMIM ID: 605736
Drug and gene relationship at DGIdb

 

Expression of UBASH3A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UBASH3A 53347 220418_at 0.1600 0.7262
GSE20347 UBASH3A 53347 220418_at -0.1344 0.0410
GSE23400 UBASH3A 53347 220418_at -0.1431 0.0000
GSE26886 UBASH3A 53347 220418_at -0.1036 0.5864
GSE29001 UBASH3A 53347 220418_at -0.1816 0.2593
GSE38129 UBASH3A 53347 220418_at -0.2340 0.0166
GSE45670 UBASH3A 53347 220418_at 0.1286 0.4983
GSE53622 UBASH3A 53347 8134 -0.4728 0.0265
GSE53624 UBASH3A 53347 162053 -0.3886 0.0008
GSE63941 UBASH3A 53347 220418_at -0.0081 0.9639
GSE77861 UBASH3A 53347 220418_at -0.0407 0.7194
GSE97050 UBASH3A 53347 A_33_P3385909 0.5597 0.4122
SRP133303 UBASH3A 53347 RNAseq -0.6735 0.0693
SRP159526 UBASH3A 53347 RNAseq -1.0221 0.1786
SRP219564 UBASH3A 53347 RNAseq 0.1601 0.7693
TCGA UBASH3A 53347 RNAseq 0.3383 0.4324

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UBASH3A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UBASH3A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UBASH3A 53347 2 8 20
GSE20123 UBASH3A 53347 2 8 20
GSE43470 UBASH3A 53347 0 13 30
GSE46452 UBASH3A 53347 1 21 37
GSE47630 UBASH3A 53347 6 17 17
GSE54993 UBASH3A 53347 8 1 61
GSE54994 UBASH3A 53347 4 8 41
GSE60625 UBASH3A 53347 0 0 11
GSE74703 UBASH3A 53347 0 10 26
GSE74704 UBASH3A 53347 1 4 15
TCGA UBASH3A 53347 7 41 48

Total number of gains: 31; Total number of losses: 131; Total Number of normals: 326.  

 

Somatic mutations of UBASH3A:

 

Generating mutation plots.

 

Highly correlated genes for UBASH3A:

 

Showing top 20/400 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UBASH3APLEKHA40.752135303
UBASH3APARP150.737286504
UBASH3ASAMD30.734203605
UBASH3APARVG0.733801505
UBASH3AARHGAP150.727955303
UBASH3AKIAA0319L0.727359303
UBASH3AFCRL30.727297404
UBASH3ASLAMF60.724141504
UBASH3ASLC29A30.722346303
UBASH3ASNX200.716704606
UBASH3ARASAL30.716067505
UBASH3ARIT20.712704404
UBASH3ACD3E0.711132908
UBASH3ACDC14A0.70485303
UBASH3AC8orf440.704602303
UBASH3ABIN20.704311808
UBASH3ACXCL130.700339403
UBASH3ASLC6A60.700072303
UBASH3AMR10.69903303
UBASH3AMAN1B10.693415303

For details and further investigation, click here