| Full name: thymocyte selection associated | Alias Symbol: bA325O24.4|FLJ40584|bA325O24.3 | ||
| Type: protein-coding gene | Cytoband: 6q22.33 | ||
| Entrez ID: 387357 | HGNC ID: HGNC:21569 | Ensembl Gene: ENSG00000172673 | OMIM ID: 613607 |
| Drug and gene relationship at DGIdb | |||
Expression of THEMIS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THEMIS | 387357 | 1558972_s_at | -0.0858 | 0.9109 | |
| GSE26886 | THEMIS | 387357 | 1558971_at | -0.4239 | 0.0287 | |
| GSE45670 | THEMIS | 387357 | 1558971_at | -0.1706 | 0.4613 | |
| GSE53622 | THEMIS | 387357 | 13873 | -1.2558 | 0.0000 | |
| GSE53624 | THEMIS | 387357 | 13873 | -1.3841 | 0.0000 | |
| GSE63941 | THEMIS | 387357 | 1558972_s_at | -0.0321 | 0.8249 | |
| GSE77861 | THEMIS | 387357 | 1558972_s_at | -0.0936 | 0.1964 | |
| SRP007169 | THEMIS | 387357 | RNAseq | -0.7424 | 0.4670 | |
| SRP133303 | THEMIS | 387357 | RNAseq | -0.6695 | 0.0909 | |
| SRP193095 | THEMIS | 387357 | RNAseq | -1.1470 | 0.0001 | |
| SRP219564 | THEMIS | 387357 | RNAseq | -0.2985 | 0.6341 | |
| TCGA | THEMIS | 387357 | RNAseq | -0.0678 | 0.8396 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by THEMIS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THEMIS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THEMIS | 387357 | 1 | 4 | 25 | |
| GSE20123 | THEMIS | 387357 | 2 | 3 | 25 | |
| GSE43470 | THEMIS | 387357 | 5 | 0 | 38 | |
| GSE46452 | THEMIS | 387357 | 2 | 11 | 46 | |
| GSE47630 | THEMIS | 387357 | 9 | 4 | 27 | |
| GSE54993 | THEMIS | 387357 | 3 | 3 | 64 | |
| GSE54994 | THEMIS | 387357 | 9 | 7 | 37 | |
| GSE60625 | THEMIS | 387357 | 0 | 1 | 10 | |
| GSE74703 | THEMIS | 387357 | 4 | 0 | 32 | |
| GSE74704 | THEMIS | 387357 | 0 | 1 | 19 | |
| TCGA | THEMIS | 387357 | 10 | 18 | 68 |
Total number of gains: 45; Total number of losses: 52; Total Number of normals: 391.
Somatic mutations of THEMIS:
Generating mutation plots.
Highly correlated genes for THEMIS:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THEMIS | CST7 | 0.782801 | 3 | 0 | 3 |
| THEMIS | NLRC3 | 0.761485 | 6 | 0 | 6 |
| THEMIS | KLRB1 | 0.735643 | 6 | 0 | 6 |
| THEMIS | NCKAP1L | 0.728222 | 3 | 0 | 3 |
| THEMIS | ITK | 0.727069 | 6 | 0 | 5 |
| THEMIS | TRAT1 | 0.725261 | 5 | 0 | 4 |
| THEMIS | ATP8B4 | 0.701071 | 3 | 0 | 3 |
| THEMIS | MS4A1 | 0.700805 | 3 | 0 | 3 |
| THEMIS | CD79B | 0.700428 | 3 | 0 | 3 |
| THEMIS | CD226 | 0.694269 | 5 | 0 | 5 |
| THEMIS | GIMAP6 | 0.694198 | 5 | 0 | 4 |
| THEMIS | HLA-DOA | 0.691161 | 3 | 0 | 3 |
| THEMIS | STAP1 | 0.685767 | 3 | 0 | 3 |
| THEMIS | ZNF831 | 0.683281 | 5 | 0 | 5 |
| THEMIS | TNFSF8 | 0.677907 | 3 | 0 | 3 |
| THEMIS | CD3E | 0.677761 | 4 | 0 | 4 |
| THEMIS | FLI1 | 0.675277 | 6 | 0 | 5 |
| THEMIS | IL2RG | 0.674466 | 4 | 0 | 4 |
| THEMIS | SASH3 | 0.673486 | 4 | 0 | 4 |
| THEMIS | CD48 | 0.671252 | 6 | 0 | 5 |
For details and further investigation, click here
