| Full name: GTPase, IMAP family member 6 | Alias Symbol: FLJ22690|IAN6 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 474344 | HGNC ID: HGNC:21918 | Ensembl Gene: ENSG00000133561 | OMIM ID: 616960 |
| Drug and gene relationship at DGIdb | |||
Expression of GIMAP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIMAP6 | 474344 | 219777_at | -0.2168 | 0.8799 | |
| GSE20347 | GIMAP6 | 474344 | 219777_at | -0.9026 | 0.0001 | |
| GSE23400 | GIMAP6 | 474344 | 219777_at | -0.0628 | 0.5539 | |
| GSE26886 | GIMAP6 | 474344 | 219777_at | -0.8779 | 0.0271 | |
| GSE29001 | GIMAP6 | 474344 | 219777_at | -0.3411 | 0.4172 | |
| GSE38129 | GIMAP6 | 474344 | 219777_at | -1.1157 | 0.0005 | |
| GSE45670 | GIMAP6 | 474344 | 219777_at | -1.3289 | 0.0024 | |
| GSE53622 | GIMAP6 | 474344 | 60015 | -0.7271 | 0.0000 | |
| GSE53624 | GIMAP6 | 474344 | 60015 | -0.5989 | 0.0001 | |
| GSE63941 | GIMAP6 | 474344 | 229367_s_at | 0.1832 | 0.3161 | |
| GSE77861 | GIMAP6 | 474344 | 229367_s_at | -0.2862 | 0.0874 | |
| GSE97050 | GIMAP6 | 474344 | A_23_P145631 | 0.3328 | 0.4079 | |
| SRP007169 | GIMAP6 | 474344 | RNAseq | 0.9456 | 0.1578 | |
| SRP008496 | GIMAP6 | 474344 | RNAseq | 0.9891 | 0.0389 | |
| SRP064894 | GIMAP6 | 474344 | RNAseq | 0.1476 | 0.6879 | |
| SRP133303 | GIMAP6 | 474344 | RNAseq | -0.7069 | 0.0125 | |
| SRP159526 | GIMAP6 | 474344 | RNAseq | -0.5691 | 0.3323 | |
| SRP193095 | GIMAP6 | 474344 | RNAseq | -0.2552 | 0.2365 | |
| SRP219564 | GIMAP6 | 474344 | RNAseq | -0.2221 | 0.6031 | |
| TCGA | GIMAP6 | 474344 | RNAseq | -0.5927 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GIMAP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIMAP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIMAP6 | 474344 | 2 | 4 | 24 | |
| GSE20123 | GIMAP6 | 474344 | 2 | 4 | 24 | |
| GSE43470 | GIMAP6 | 474344 | 2 | 5 | 36 | |
| GSE46452 | GIMAP6 | 474344 | 7 | 2 | 50 | |
| GSE47630 | GIMAP6 | 474344 | 5 | 9 | 26 | |
| GSE54993 | GIMAP6 | 474344 | 3 | 3 | 64 | |
| GSE54994 | GIMAP6 | 474344 | 6 | 8 | 39 | |
| GSE60625 | GIMAP6 | 474344 | 0 | 0 | 11 | |
| GSE74703 | GIMAP6 | 474344 | 2 | 4 | 30 | |
| GSE74704 | GIMAP6 | 474344 | 1 | 4 | 15 | |
| TCGA | GIMAP6 | 474344 | 26 | 27 | 43 |
Total number of gains: 56; Total number of losses: 70; Total Number of normals: 362.
Somatic mutations of GIMAP6:
Generating mutation plots.
Highly correlated genes for GIMAP6:
Showing top 20/1036 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIMAP6 | GIMAP4 | 0.847948 | 11 | 0 | 11 |
| GIMAP6 | GIMAP1 | 0.847107 | 7 | 0 | 7 |
| GIMAP6 | MPEG1 | 0.846644 | 6 | 0 | 6 |
| GIMAP6 | GIMAP7 | 0.817236 | 8 | 0 | 8 |
| GIMAP6 | GIMAP5 | 0.807159 | 4 | 0 | 3 |
| GIMAP6 | ARHGAP15 | 0.796802 | 4 | 0 | 4 |
| GIMAP6 | GIMAP8 | 0.780596 | 7 | 0 | 6 |
| GIMAP6 | NOA1 | 0.773955 | 3 | 0 | 3 |
| GIMAP6 | PDE7B | 0.757558 | 5 | 0 | 5 |
| GIMAP6 | FLI1 | 0.757535 | 10 | 0 | 8 |
| GIMAP6 | SLC16A4 | 0.756872 | 6 | 0 | 6 |
| GIMAP6 | SUCNR1 | 0.746232 | 3 | 0 | 3 |
| GIMAP6 | RGS18 | 0.745608 | 7 | 0 | 7 |
| GIMAP6 | ARHGAP31 | 0.737504 | 5 | 0 | 5 |
| GIMAP6 | ARHGEF6 | 0.731532 | 12 | 0 | 11 |
| GIMAP6 | CCR2 | 0.729266 | 9 | 0 | 7 |
| GIMAP6 | SLIT3 | 0.727539 | 3 | 0 | 3 |
| GIMAP6 | SHE | 0.724706 | 5 | 0 | 5 |
| GIMAP6 | TNFSF8 | 0.724318 | 5 | 0 | 4 |
| GIMAP6 | EVI2A | 0.723805 | 8 | 0 | 8 |
For details and further investigation, click here
