| Full name: KN motif and ankyrin repeat domains 3 | Alias Symbol: FLJ46061 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 256949 | HGNC ID: HGNC:24796 | Ensembl Gene: ENSG00000186994 | OMIM ID: 614611 |
| Drug and gene relationship at DGIdb | |||
Expression of KANK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KANK3 | 256949 | 213715_s_at | -0.4293 | 0.1913 | |
| GSE20347 | KANK3 | 256949 | 213715_s_at | -0.1627 | 0.0212 | |
| GSE23400 | KANK3 | 256949 | 213715_s_at | -0.1792 | 0.0000 | |
| GSE26886 | KANK3 | 256949 | 213715_s_at | 0.0967 | 0.5951 | |
| GSE29001 | KANK3 | 256949 | 213715_s_at | -0.4393 | 0.0009 | |
| GSE38129 | KANK3 | 256949 | 213715_s_at | -0.5792 | 0.0029 | |
| GSE45670 | KANK3 | 256949 | 213715_s_at | -0.4112 | 0.0157 | |
| GSE53622 | KANK3 | 256949 | 112821 | 0.5125 | 0.0000 | |
| GSE53624 | KANK3 | 256949 | 112821 | 0.3760 | 0.0000 | |
| GSE63941 | KANK3 | 256949 | 213715_s_at | 0.3821 | 0.0296 | |
| GSE77861 | KANK3 | 256949 | 213715_s_at | -0.2440 | 0.1711 | |
| GSE97050 | KANK3 | 256949 | A_33_P3326020 | 0.2023 | 0.3588 | |
| SRP007169 | KANK3 | 256949 | RNAseq | -1.9780 | 0.0003 | |
| SRP064894 | KANK3 | 256949 | RNAseq | -0.2292 | 0.3882 | |
| SRP133303 | KANK3 | 256949 | RNAseq | -1.2175 | 0.0013 | |
| SRP159526 | KANK3 | 256949 | RNAseq | -0.9824 | 0.0001 | |
| SRP193095 | KANK3 | 256949 | RNAseq | -0.2536 | 0.2203 | |
| SRP219564 | KANK3 | 256949 | RNAseq | -0.4572 | 0.4894 | |
| TCGA | KANK3 | 256949 | RNAseq | -0.8063 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KANK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KANK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KANK3 | 256949 | 4 | 3 | 23 | |
| GSE20123 | KANK3 | 256949 | 3 | 2 | 25 | |
| GSE43470 | KANK3 | 256949 | 2 | 6 | 35 | |
| GSE46452 | KANK3 | 256949 | 47 | 1 | 11 | |
| GSE47630 | KANK3 | 256949 | 5 | 7 | 28 | |
| GSE54993 | KANK3 | 256949 | 16 | 3 | 51 | |
| GSE54994 | KANK3 | 256949 | 6 | 14 | 33 | |
| GSE60625 | KANK3 | 256949 | 9 | 0 | 2 | |
| GSE74703 | KANK3 | 256949 | 2 | 4 | 30 | |
| GSE74704 | KANK3 | 256949 | 0 | 2 | 18 | |
| TCGA | KANK3 | 256949 | 10 | 19 | 67 |
Total number of gains: 104; Total number of losses: 61; Total Number of normals: 323.
Somatic mutations of KANK3:
Generating mutation plots.
Highly correlated genes for KANK3:
Showing top 20/265 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KANK3 | ZDHHC20 | 0.86178 | 3 | 0 | 3 |
| KANK3 | LDHAL6A | 0.846312 | 4 | 0 | 4 |
| KANK3 | ZNF763 | 0.764629 | 5 | 0 | 4 |
| KANK3 | RAX2 | 0.752761 | 3 | 0 | 3 |
| KANK3 | NKX6-3 | 0.749148 | 3 | 0 | 3 |
| KANK3 | GPR146 | 0.746103 | 3 | 0 | 3 |
| KANK3 | MRGPRG | 0.743331 | 3 | 0 | 3 |
| KANK3 | DCDC1 | 0.735437 | 3 | 0 | 3 |
| KANK3 | WDR38 | 0.735081 | 3 | 0 | 3 |
| KANK3 | KLF17 | 0.733844 | 4 | 0 | 3 |
| KANK3 | ZNF527 | 0.728981 | 4 | 0 | 3 |
| KANK3 | C9orf153 | 0.725686 | 3 | 0 | 3 |
| KANK3 | LHB | 0.720818 | 3 | 0 | 3 |
| KANK3 | SCARA5 | 0.71659 | 3 | 0 | 3 |
| KANK3 | PHOSPHO1 | 0.711613 | 4 | 0 | 4 |
| KANK3 | GJD4 | 0.707541 | 6 | 0 | 6 |
| KANK3 | LBX2 | 0.700364 | 3 | 0 | 3 |
| KANK3 | KCNH3 | 0.698003 | 4 | 0 | 4 |
| KANK3 | NXF5 | 0.696302 | 3 | 0 | 3 |
| KANK3 | CLEC4G | 0.692768 | 4 | 0 | 4 |
For details and further investigation, click here
