| Full name: autophagy related 14 | Alias Symbol: ATG14L | ||
| Type: protein-coding gene | Cytoband: 14q22.3 | ||
| Entrez ID: 22863 | HGNC ID: HGNC:19962 | Ensembl Gene: ENSG00000126775 | OMIM ID: 613515 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG14 | 22863 | 204568_at | 0.0111 | 0.9886 | |
| GSE20347 | ATG14 | 22863 | 204568_at | 0.0347 | 0.8284 | |
| GSE23400 | ATG14 | 22863 | 204568_at | 0.1245 | 0.1429 | |
| GSE26886 | ATG14 | 22863 | 204568_at | 0.0558 | 0.8841 | |
| GSE29001 | ATG14 | 22863 | 204568_at | -0.0210 | 0.9297 | |
| GSE38129 | ATG14 | 22863 | 204568_at | -0.1032 | 0.3958 | |
| GSE45670 | ATG14 | 22863 | 204568_at | -0.2856 | 0.0176 | |
| GSE53622 | ATG14 | 22863 | 13025 | 0.0151 | 0.8868 | |
| GSE53624 | ATG14 | 22863 | 13025 | -0.0318 | 0.7046 | |
| GSE63941 | ATG14 | 22863 | 204568_at | -0.2326 | 0.5813 | |
| GSE77861 | ATG14 | 22863 | 204568_at | 0.2509 | 0.5691 | |
| GSE97050 | ATG14 | 22863 | A_23_P309989 | -0.2445 | 0.3220 | |
| SRP007169 | ATG14 | 22863 | RNAseq | -0.4114 | 0.3320 | |
| SRP008496 | ATG14 | 22863 | RNAseq | -0.5702 | 0.0379 | |
| SRP064894 | ATG14 | 22863 | RNAseq | -0.1756 | 0.2625 | |
| SRP133303 | ATG14 | 22863 | RNAseq | -0.1313 | 0.5489 | |
| SRP159526 | ATG14 | 22863 | RNAseq | -0.3605 | 0.2764 | |
| SRP193095 | ATG14 | 22863 | RNAseq | -0.2934 | 0.0022 | |
| SRP219564 | ATG14 | 22863 | RNAseq | 0.0090 | 0.9775 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATG14 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ATG14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG14 | 22863 | 8 | 3 | 19 | |
| GSE20123 | ATG14 | 22863 | 8 | 3 | 19 | |
| GSE43470 | ATG14 | 22863 | 9 | 1 | 33 | |
| GSE46452 | ATG14 | 22863 | 16 | 3 | 40 | |
| GSE47630 | ATG14 | 22863 | 11 | 10 | 19 | |
| GSE54993 | ATG14 | 22863 | 3 | 8 | 59 | |
| GSE54994 | ATG14 | 22863 | 19 | 4 | 30 | |
| GSE60625 | ATG14 | 22863 | 0 | 2 | 9 | |
| GSE74703 | ATG14 | 22863 | 8 | 1 | 27 | |
| GSE74704 | ATG14 | 22863 | 3 | 2 | 15 | |
| TCGA | ATG14 | 22863 | 32 | 14 | 50 |
Total number of gains: 117; Total number of losses: 51; Total Number of normals: 320.
Somatic mutations of ATG14:
Generating mutation plots.
Highly correlated genes for ATG14:
Showing top 20/196 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG14 | BRWD1 | 0.798318 | 3 | 0 | 3 |
| ATG14 | ZNF805 | 0.793473 | 3 | 0 | 3 |
| ATG14 | ASH1L | 0.783394 | 3 | 0 | 3 |
| ATG14 | USP19 | 0.754026 | 3 | 0 | 3 |
| ATG14 | ZNF615 | 0.75357 | 3 | 0 | 3 |
| ATG14 | UPF3B | 0.753468 | 4 | 0 | 4 |
| ATG14 | KANSL2 | 0.744503 | 4 | 0 | 4 |
| ATG14 | FRA10AC1 | 0.741704 | 4 | 0 | 4 |
| ATG14 | ZNF227 | 0.72856 | 4 | 0 | 4 |
| ATG14 | C2orf42 | 0.721534 | 3 | 0 | 3 |
| ATG14 | C9orf78 | 0.718771 | 3 | 0 | 3 |
| ATG14 | PPP2R3C | 0.718478 | 3 | 0 | 3 |
| ATG14 | LCOR | 0.712915 | 4 | 0 | 4 |
| ATG14 | ZNF354C | 0.712756 | 3 | 0 | 3 |
| ATG14 | CBLL1 | 0.711185 | 3 | 0 | 3 |
| ATG14 | PRPF4B | 0.708156 | 3 | 0 | 3 |
| ATG14 | G2E3 | 0.707649 | 3 | 0 | 3 |
| ATG14 | ATAD1 | 0.706485 | 3 | 0 | 3 |
| ATG14 | ARID2 | 0.701404 | 4 | 0 | 4 |
| ATG14 | CDKN2C | 0.701364 | 3 | 0 | 3 |
For details and further investigation, click here
