| Full name: Kazal type serine peptidase inhibitor domain 1 | Alias Symbol: FKSG40|FKSG28 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 81621 | HGNC ID: HGNC:25460 | Ensembl Gene: ENSG00000107821 | OMIM ID: 609208 |
| Drug and gene relationship at DGIdb | |||
Expression of KAZALD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KAZALD1 | 81621 | 221000_s_at | 0.0230 | 0.9453 | |
| GSE20347 | KAZALD1 | 81621 | 217511_at | -0.0876 | 0.2343 | |
| GSE23400 | KAZALD1 | 81621 | 217511_at | -0.2712 | 0.0000 | |
| GSE26886 | KAZALD1 | 81621 | 221000_s_at | 0.3743 | 0.0025 | |
| GSE29001 | KAZALD1 | 81621 | 221000_s_at | 0.0257 | 0.9329 | |
| GSE38129 | KAZALD1 | 81621 | 217511_at | -0.1597 | 0.0697 | |
| GSE45670 | KAZALD1 | 81621 | 221000_s_at | 0.1230 | 0.2748 | |
| GSE53622 | KAZALD1 | 81621 | 6300 | -0.2500 | 0.1202 | |
| GSE53624 | KAZALD1 | 81621 | 6300 | -0.1172 | 0.3818 | |
| GSE63941 | KAZALD1 | 81621 | 217511_at | -0.3109 | 0.2479 | |
| GSE77861 | KAZALD1 | 81621 | 1568598_at | -0.0115 | 0.9391 | |
| GSE97050 | KAZALD1 | 81621 | A_24_P192727 | 0.2635 | 0.4373 | |
| SRP064894 | KAZALD1 | 81621 | RNAseq | -0.3544 | 0.5164 | |
| SRP133303 | KAZALD1 | 81621 | RNAseq | -0.0415 | 0.9290 | |
| SRP159526 | KAZALD1 | 81621 | RNAseq | 0.9066 | 0.0765 | |
| SRP193095 | KAZALD1 | 81621 | RNAseq | -0.2628 | 0.5090 | |
| SRP219564 | KAZALD1 | 81621 | RNAseq | 1.1312 | 0.0814 | |
| TCGA | KAZALD1 | 81621 | RNAseq | -1.0719 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KAZALD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KAZALD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KAZALD1 | 81621 | 1 | 8 | 21 | |
| GSE20123 | KAZALD1 | 81621 | 1 | 7 | 22 | |
| GSE43470 | KAZALD1 | 81621 | 0 | 8 | 35 | |
| GSE46452 | KAZALD1 | 81621 | 0 | 11 | 48 | |
| GSE47630 | KAZALD1 | 81621 | 2 | 14 | 24 | |
| GSE54993 | KAZALD1 | 81621 | 8 | 0 | 62 | |
| GSE54994 | KAZALD1 | 81621 | 1 | 12 | 40 | |
| GSE60625 | KAZALD1 | 81621 | 0 | 0 | 11 | |
| GSE74703 | KAZALD1 | 81621 | 0 | 5 | 31 | |
| GSE74704 | KAZALD1 | 81621 | 0 | 4 | 16 | |
| TCGA | KAZALD1 | 81621 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of KAZALD1:
Generating mutation plots.
Highly correlated genes for KAZALD1:
Showing top 20/485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KAZALD1 | CCL26 | 0.807425 | 3 | 0 | 3 |
| KAZALD1 | PPP1R27 | 0.77166 | 3 | 0 | 3 |
| KAZALD1 | SMOC1 | 0.759082 | 3 | 0 | 3 |
| KAZALD1 | ASPDH | 0.758278 | 3 | 0 | 3 |
| KAZALD1 | JSRP1 | 0.737603 | 3 | 0 | 3 |
| KAZALD1 | HSD17B14 | 0.732803 | 3 | 0 | 3 |
| KAZALD1 | RIMS4 | 0.695334 | 3 | 0 | 3 |
| KAZALD1 | VAV2 | 0.690714 | 3 | 0 | 3 |
| KAZALD1 | RENBP | 0.687905 | 3 | 0 | 3 |
| KAZALD1 | PHF1 | 0.686491 | 3 | 0 | 3 |
| KAZALD1 | BAHCC1 | 0.677851 | 4 | 0 | 3 |
| KAZALD1 | SRRM3 | 0.677113 | 3 | 0 | 3 |
| KAZALD1 | C10orf91 | 0.666937 | 4 | 0 | 4 |
| KAZALD1 | HOXD9 | 0.666783 | 4 | 0 | 3 |
| KAZALD1 | IPO13 | 0.662909 | 4 | 0 | 4 |
| KAZALD1 | GFRA2 | 0.661642 | 5 | 0 | 5 |
| KAZALD1 | CACNA1G | 0.660905 | 6 | 0 | 5 |
| KAZALD1 | SYCE1L | 0.660811 | 3 | 0 | 3 |
| KAZALD1 | CYP11B1 | 0.658875 | 8 | 0 | 6 |
| KAZALD1 | ADM2 | 0.654468 | 6 | 0 | 5 |
For details and further investigation, click here
