| Full name: protein phosphatase 1 regulatory subunit 27 | Alias Symbol: toonin | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 116729 | HGNC ID: HGNC:16813 | Ensembl Gene: ENSG00000182676 | OMIM ID: |
Expression of PPP1R27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R27 | 116729 | 1557480_a_at | -0.0230 | 0.9367 | |
| GSE26886 | PPP1R27 | 116729 | 1557480_a_at | -0.0913 | 0.4969 | |
| GSE45670 | PPP1R27 | 116729 | 1557480_a_at | 0.1686 | 0.0357 | |
| GSE53622 | PPP1R27 | 116729 | 57297 | 0.6129 | 0.0000 | |
| GSE53624 | PPP1R27 | 116729 | 57297 | 0.6000 | 0.0000 | |
| GSE63941 | PPP1R27 | 116729 | 1557480_a_at | 0.4743 | 0.0303 | |
| GSE77861 | PPP1R27 | 116729 | 1557480_a_at | -0.0584 | 0.5835 | |
| GSE97050 | PPP1R27 | 116729 | A_33_P3287472 | -0.3586 | 0.6129 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP1R27 expression:
Note: Click image to view full size file.
Copy number change of PPP1R27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R27 | 116729 | 4 | 4 | 22 | |
| GSE20123 | PPP1R27 | 116729 | 4 | 4 | 22 | |
| GSE43470 | PPP1R27 | 116729 | 3 | 5 | 35 | |
| GSE46452 | PPP1R27 | 116729 | 34 | 0 | 25 | |
| GSE47630 | PPP1R27 | 116729 | 9 | 2 | 29 | |
| GSE54993 | PPP1R27 | 116729 | 2 | 5 | 63 | |
| GSE54994 | PPP1R27 | 116729 | 10 | 6 | 37 | |
| GSE60625 | PPP1R27 | 116729 | 6 | 0 | 5 | |
| GSE74703 | PPP1R27 | 116729 | 3 | 3 | 30 | |
| GSE74704 | PPP1R27 | 116729 | 4 | 3 | 13 | |
| TCGA | PPP1R27 | 116729 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of PPP1R27:
Generating mutation plots.
Highly correlated genes for PPP1R27:
Showing top 20/206 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R27 | KAZALD1 | 0.77166 | 3 | 0 | 3 |
| PPP1R27 | SIRPD | 0.731811 | 3 | 0 | 3 |
| PPP1R27 | RNF144A-AS1 | 0.727442 | 3 | 0 | 3 |
| PPP1R27 | LINC00410 | 0.703459 | 3 | 0 | 3 |
| PPP1R27 | TP53TG5 | 0.688886 | 4 | 0 | 4 |
| PPP1R27 | ADRA1B | 0.681487 | 3 | 0 | 3 |
| PPP1R27 | UPB1 | 0.663122 | 3 | 0 | 3 |
| PPP1R27 | LIME1 | 0.65698 | 4 | 0 | 4 |
| PPP1R27 | GGTLC1 | 0.650402 | 3 | 0 | 3 |
| PPP1R27 | DRD2 | 0.646357 | 4 | 0 | 3 |
| PPP1R27 | MAMSTR | 0.638338 | 4 | 0 | 4 |
| PPP1R27 | MAGIX | 0.632364 | 4 | 0 | 3 |
| PPP1R27 | NFIA-AS2 | 0.630538 | 4 | 0 | 3 |
| PPP1R27 | AANAT | 0.629182 | 3 | 0 | 3 |
| PPP1R27 | CAMK2B | 0.627165 | 4 | 0 | 4 |
| PPP1R27 | ASPDH | 0.626685 | 4 | 0 | 3 |
| PPP1R27 | ADH6 | 0.625836 | 4 | 0 | 3 |
| PPP1R27 | IGSF21 | 0.625625 | 3 | 0 | 3 |
| PPP1R27 | CPA5 | 0.624667 | 3 | 0 | 3 |
| PPP1R27 | LINC01343 | 0.622912 | 3 | 0 | 3 |
For details and further investigation, click here

