SPRR2F

 

Full name: small proline rich protein 2F Alias Symbol: 
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 6705 HGNC ID: HGNC:11266 Ensembl Gene: ENSG00000244094 OMIM ID: 617589
Drug and gene relationship at DGIdb

 

Expression of SPRR2F:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 SPRR2F 6705 41019 -1.8652 0.0000
GSE53624 SPRR2F 6705 41019 -2.6589 0.0000
GSE97050 SPRR2F 6705 A_33_P3274811 -0.1354 0.7695
SRP007169 SPRR2F 6705 RNAseq -6.2804 0.0000
SRP008496 SPRR2F 6705 RNAseq -5.0476 0.0000
SRP133303 SPRR2F 6705 RNAseq -0.5646 0.4317
SRP159526 SPRR2F 6705 RNAseq -2.7466 0.0852
TCGA SPRR2F 6705 RNAseq 1.1047 0.0929

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by SPRR2F expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SPRR2F:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SPRR2F 6705 15 0 15
GSE20123 SPRR2F 6705 15 0 15
GSE43470 SPRR2F 6705 6 2 35
GSE46452 SPRR2F 6705 3 1 55
GSE47630 SPRR2F 6705 15 0 25
GSE54993 SPRR2F 6705 0 4 66
GSE54994 SPRR2F 6705 16 0 37
GSE60625 SPRR2F 6705 0 0 11
GSE74703 SPRR2F 6705 6 1 29
GSE74704 SPRR2F 6705 7 0 13
TCGA SPRR2F 6705 39 2 55

Total number of gains: 122; Total number of losses: 10; Total Number of normals: 356.  


 

Somatic mutations of SPRR2F:

 

Generating mutation plots.

 

Highly correlated genes for SPRR2F:

 

Showing top 20/363 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SPRR2FSPRR2A0.979976404
SPRR2FSPRR2E0.975385404
SPRR2FSPRR2D0.97316404
SPRR2FGPR450.925062303
SPRR2FSPRR1B0.895386404
SPRR2FCNFN0.885192404
SPRR2FSPRR1A0.882916404
SPRR2FSBSN0.871689404
SPRR2FIL36A0.868347303
SPRR2FC19orf570.860174303
SPRR2FTMPRSS11E0.853862303
SPRR2FSPRR2B0.852931404
SPRR2FP2RX30.839222303
SPRR2FCEACAM30.838175303
SPRR2FGRHL30.832703404
SPRR2FVSIG10L0.830586303
SPRR2FIQCF10.829047303
SPRR2FS100A90.828259404
SPRR2FPGLYRP30.82052303
SPRR2FTGM10.819677404

For details and further investigation, click here