| Full name: small proline rich protein 2F | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6705 | HGNC ID: HGNC:11266 | Ensembl Gene: ENSG00000244094 | OMIM ID: 617589 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRR2F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SPRR2F | 6705 | 41019 | -1.8652 | 0.0000 | |
| GSE53624 | SPRR2F | 6705 | 41019 | -2.6589 | 0.0000 | |
| GSE97050 | SPRR2F | 6705 | A_33_P3274811 | -0.1354 | 0.7695 | |
| SRP007169 | SPRR2F | 6705 | RNAseq | -6.2804 | 0.0000 | |
| SRP008496 | SPRR2F | 6705 | RNAseq | -5.0476 | 0.0000 | |
| SRP133303 | SPRR2F | 6705 | RNAseq | -0.5646 | 0.4317 | |
| SRP159526 | SPRR2F | 6705 | RNAseq | -2.7466 | 0.0852 | |
| TCGA | SPRR2F | 6705 | RNAseq | 1.1047 | 0.0929 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SPRR2F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRR2F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRR2F | 6705 | 15 | 0 | 15 | |
| GSE20123 | SPRR2F | 6705 | 15 | 0 | 15 | |
| GSE43470 | SPRR2F | 6705 | 6 | 2 | 35 | |
| GSE46452 | SPRR2F | 6705 | 3 | 1 | 55 | |
| GSE47630 | SPRR2F | 6705 | 15 | 0 | 25 | |
| GSE54993 | SPRR2F | 6705 | 0 | 4 | 66 | |
| GSE54994 | SPRR2F | 6705 | 16 | 0 | 37 | |
| GSE60625 | SPRR2F | 6705 | 0 | 0 | 11 | |
| GSE74703 | SPRR2F | 6705 | 6 | 1 | 29 | |
| GSE74704 | SPRR2F | 6705 | 7 | 0 | 13 | |
| TCGA | SPRR2F | 6705 | 39 | 2 | 55 |
Total number of gains: 122; Total number of losses: 10; Total Number of normals: 356.
Somatic mutations of SPRR2F:
Generating mutation plots.
Highly correlated genes for SPRR2F:
Showing top 20/363 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRR2F | SPRR2A | 0.979976 | 4 | 0 | 4 |
| SPRR2F | SPRR2E | 0.975385 | 4 | 0 | 4 |
| SPRR2F | SPRR2D | 0.97316 | 4 | 0 | 4 |
| SPRR2F | GPR45 | 0.925062 | 3 | 0 | 3 |
| SPRR2F | SPRR1B | 0.895386 | 4 | 0 | 4 |
| SPRR2F | CNFN | 0.885192 | 4 | 0 | 4 |
| SPRR2F | SPRR1A | 0.882916 | 4 | 0 | 4 |
| SPRR2F | SBSN | 0.871689 | 4 | 0 | 4 |
| SPRR2F | IL36A | 0.868347 | 3 | 0 | 3 |
| SPRR2F | C19orf57 | 0.860174 | 3 | 0 | 3 |
| SPRR2F | TMPRSS11E | 0.853862 | 3 | 0 | 3 |
| SPRR2F | SPRR2B | 0.852931 | 4 | 0 | 4 |
| SPRR2F | P2RX3 | 0.839222 | 3 | 0 | 3 |
| SPRR2F | CEACAM3 | 0.838175 | 3 | 0 | 3 |
| SPRR2F | GRHL3 | 0.832703 | 4 | 0 | 4 |
| SPRR2F | VSIG10L | 0.830586 | 3 | 0 | 3 |
| SPRR2F | IQCF1 | 0.829047 | 3 | 0 | 3 |
| SPRR2F | S100A9 | 0.828259 | 4 | 0 | 4 |
| SPRR2F | PGLYRP3 | 0.82052 | 3 | 0 | 3 |
| SPRR2F | TGM1 | 0.819677 | 4 | 0 | 4 |
For details and further investigation, click here
