SNRNP70

 

Full name: small nuclear ribonucleoprotein U1 subunit 70 Alias Symbol: U1-70K|Snp1
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 6625 HGNC ID: HGNC:11150 Ensembl Gene: ENSG00000104852 OMIM ID: 180740
Drug and gene relationship at DGIdb

 

Expression of SNRNP70:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNRNP70 6625 201221_s_at 0.3396 0.5462
GSE20347 SNRNP70 6625 201221_s_at 0.2455 0.0736
GSE23400 SNRNP70 6625 201221_s_at 0.2754 0.0003
GSE26886 SNRNP70 6625 201221_s_at 0.3745 0.1712
GSE29001 SNRNP70 6625 201221_s_at 0.1541 0.7306
GSE38129 SNRNP70 6625 201221_s_at 0.2941 0.0236
GSE45670 SNRNP70 6625 201221_s_at 0.0550 0.6964
GSE53622 SNRNP70 6625 68667 0.1321 0.0024
GSE53624 SNRNP70 6625 68667 0.3170 0.0000
GSE63941 SNRNP70 6625 201221_s_at 0.4458 0.0945
GSE77861 SNRNP70 6625 201221_s_at 0.6692 0.0025
GSE97050 SNRNP70 6625 A_23_P4909 -0.1922 0.4296
SRP007169 SNRNP70 6625 RNAseq 1.1436 0.0125
SRP008496 SNRNP70 6625 RNAseq 0.9436 0.0192
SRP064894 SNRNP70 6625 RNAseq 0.5897 0.0199
SRP133303 SNRNP70 6625 RNAseq -0.0391 0.7357
SRP159526 SNRNP70 6625 RNAseq 0.1023 0.7124
SRP193095 SNRNP70 6625 RNAseq 0.3431 0.0243
SRP219564 SNRNP70 6625 RNAseq 0.1536 0.6019
TCGA SNRNP70 6625 RNAseq 0.0254 0.5507

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SNRNP70 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SNRNP70:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNRNP70 6625 4 4 22
GSE20123 SNRNP70 6625 4 3 23
GSE43470 SNRNP70 6625 4 10 29
GSE46452 SNRNP70 6625 45 1 13
GSE47630 SNRNP70 6625 9 6 25
GSE54993 SNRNP70 6625 17 4 49
GSE54994 SNRNP70 6625 4 14 35
GSE60625 SNRNP70 6625 9 0 2
GSE74703 SNRNP70 6625 4 7 25
GSE74704 SNRNP70 6625 4 1 15
TCGA SNRNP70 6625 14 18 64

Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.  

 

Somatic mutations of SNRNP70:

 

Generating mutation plots.

 

Highly correlated genes for SNRNP70:

 

Showing top 20/728 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNRNP70GATAD2B0.776252303
SNRNP70ZNF518B0.760429303
SNRNP70TMEM63B0.751027303
SNRNP70ARF10.749406303
SNRNP70TEX100.745609303
SNRNP70ZNF2510.74375303
SNRNP70KHNYN0.743744303
SNRNP70ATP2B40.73226303
SNRNP70KCTD150.726865303
SNRNP70STK30.722566303
SNRNP70ZMYND190.720472303
SNRNP70TERF10.707544403
SNRNP70TMTC40.706287303
SNRNP70MOB3A0.702049303
SNRNP70YWHAG0.698314403
SNRNP70GAK0.698015404
SNRNP70ITPKB0.695757303
SNRNP70ALKBH60.692273403
SNRNP70DPH70.692177403
SNRNP70RPRD20.688559404

For details and further investigation, click here