| Full name: ADP ribosylation factor like GTPase 6 interacting protein 6 | Alias Symbol: MGC33864 | ||
| Type: protein-coding gene | Cytoband: 2q23.3 | ||
| Entrez ID: 151188 | HGNC ID: HGNC:24048 | Ensembl Gene: ENSG00000177917 | OMIM ID: 616495 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL6IP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL6IP6 | 151188 | 225707_at | 0.7647 | 0.1662 | |
| GSE26886 | ARL6IP6 | 151188 | 225707_at | 0.6177 | 0.0077 | |
| GSE45670 | ARL6IP6 | 151188 | 225707_at | 0.4616 | 0.0123 | |
| GSE53622 | ARL6IP6 | 151188 | 34454 | 0.9010 | 0.0000 | |
| GSE53624 | ARL6IP6 | 151188 | 34454 | 0.8639 | 0.0000 | |
| GSE63941 | ARL6IP6 | 151188 | 225707_at | 1.1756 | 0.0100 | |
| GSE77861 | ARL6IP6 | 151188 | 225707_at | 0.5709 | 0.0635 | |
| GSE97050 | ARL6IP6 | 151188 | A_23_P28169 | 0.3953 | 0.2237 | |
| SRP007169 | ARL6IP6 | 151188 | RNAseq | 0.5659 | 0.1976 | |
| SRP008496 | ARL6IP6 | 151188 | RNAseq | 0.8010 | 0.0057 | |
| SRP064894 | ARL6IP6 | 151188 | RNAseq | 0.7323 | 0.0096 | |
| SRP133303 | ARL6IP6 | 151188 | RNAseq | 0.4492 | 0.0016 | |
| SRP159526 | ARL6IP6 | 151188 | RNAseq | 0.4634 | 0.0193 | |
| SRP193095 | ARL6IP6 | 151188 | RNAseq | 0.0553 | 0.5999 | |
| SRP219564 | ARL6IP6 | 151188 | RNAseq | 0.0992 | 0.8261 | |
| TCGA | ARL6IP6 | 151188 | RNAseq | 0.4733 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARL6IP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL6IP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL6IP6 | 151188 | 3 | 2 | 25 | |
| GSE20123 | ARL6IP6 | 151188 | 3 | 2 | 25 | |
| GSE43470 | ARL6IP6 | 151188 | 3 | 1 | 39 | |
| GSE46452 | ARL6IP6 | 151188 | 1 | 4 | 54 | |
| GSE47630 | ARL6IP6 | 151188 | 5 | 3 | 32 | |
| GSE54993 | ARL6IP6 | 151188 | 0 | 5 | 65 | |
| GSE54994 | ARL6IP6 | 151188 | 11 | 2 | 40 | |
| GSE60625 | ARL6IP6 | 151188 | 0 | 3 | 8 | |
| GSE74703 | ARL6IP6 | 151188 | 2 | 1 | 33 | |
| GSE74704 | ARL6IP6 | 151188 | 2 | 0 | 18 | |
| TCGA | ARL6IP6 | 151188 | 21 | 8 | 67 |
Total number of gains: 51; Total number of losses: 31; Total Number of normals: 406.
Somatic mutations of ARL6IP6:
Generating mutation plots.
Highly correlated genes for ARL6IP6:
Showing top 20/1625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL6IP6 | MMS22L | 0.796653 | 3 | 0 | 3 |
| ARL6IP6 | KHNYN | 0.747656 | 3 | 0 | 3 |
| ARL6IP6 | ZDHHC4 | 0.742005 | 3 | 0 | 3 |
| ARL6IP6 | BORA | 0.737437 | 6 | 0 | 6 |
| ARL6IP6 | UBE2E3 | 0.731152 | 7 | 0 | 7 |
| ARL6IP6 | GABPB1 | 0.73051 | 4 | 0 | 4 |
| ARL6IP6 | GSS | 0.729116 | 3 | 0 | 3 |
| ARL6IP6 | RMND1 | 0.72903 | 3 | 0 | 3 |
| ARL6IP6 | PDIA6 | 0.728241 | 7 | 0 | 6 |
| ARL6IP6 | FMNL2 | 0.728036 | 7 | 0 | 7 |
| ARL6IP6 | PSME4 | 0.726866 | 7 | 0 | 7 |
| ARL6IP6 | HAT1 | 0.726075 | 9 | 0 | 9 |
| ARL6IP6 | CCT6A | 0.725189 | 4 | 0 | 3 |
| ARL6IP6 | CSE1L | 0.724769 | 6 | 0 | 6 |
| ARL6IP6 | MTHFD1L | 0.721899 | 3 | 0 | 3 |
| ARL6IP6 | RIMKLB | 0.720234 | 3 | 0 | 3 |
| ARL6IP6 | NDC80 | 0.71943 | 7 | 0 | 7 |
| ARL6IP6 | C1orf112 | 0.719252 | 6 | 0 | 6 |
| ARL6IP6 | DCAF13 | 0.718862 | 6 | 0 | 5 |
| ARL6IP6 | ZBED4 | 0.718632 | 3 | 0 | 3 |
For details and further investigation, click here
