| Full name: GLE1 RNA export mediator | Alias Symbol: hGLE1 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 2733 | HGNC ID: HGNC:4315 | Ensembl Gene: ENSG00000119392 | OMIM ID: 603371 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GLE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLE1 | 2733 | 225371_at | 0.2952 | 0.3794 | |
| GSE20347 | GLE1 | 2733 | 206920_s_at | 0.1625 | 0.0787 | |
| GSE23400 | GLE1 | 2733 | 206920_s_at | 0.1284 | 0.0010 | |
| GSE26886 | GLE1 | 2733 | 225371_at | 0.2519 | 0.2275 | |
| GSE29001 | GLE1 | 2733 | 206920_s_at | -0.0569 | 0.7404 | |
| GSE38129 | GLE1 | 2733 | 206920_s_at | 0.1431 | 0.0722 | |
| GSE45670 | GLE1 | 2733 | 225371_at | 0.4481 | 0.0047 | |
| GSE53622 | GLE1 | 2733 | 5465 | 0.4534 | 0.0000 | |
| GSE53624 | GLE1 | 2733 | 5465 | 0.5717 | 0.0000 | |
| GSE63941 | GLE1 | 2733 | 225371_at | 0.7069 | 0.1049 | |
| GSE77861 | GLE1 | 2733 | 225371_at | 0.2612 | 0.0846 | |
| GSE97050 | GLE1 | 2733 | A_23_P258367 | 0.0490 | 0.8667 | |
| SRP007169 | GLE1 | 2733 | RNAseq | 0.4090 | 0.3755 | |
| SRP008496 | GLE1 | 2733 | RNAseq | 0.2211 | 0.4251 | |
| SRP064894 | GLE1 | 2733 | RNAseq | 0.5590 | 0.0024 | |
| SRP133303 | GLE1 | 2733 | RNAseq | 0.2627 | 0.1966 | |
| SRP159526 | GLE1 | 2733 | RNAseq | 0.2707 | 0.1588 | |
| SRP193095 | GLE1 | 2733 | RNAseq | 0.0646 | 0.5389 | |
| SRP219564 | GLE1 | 2733 | RNAseq | 0.2342 | 0.4253 | |
| TCGA | GLE1 | 2733 | RNAseq | 0.2031 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GLE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLE1 | 2733 | 6 | 9 | 15 | |
| GSE20123 | GLE1 | 2733 | 6 | 9 | 15 | |
| GSE43470 | GLE1 | 2733 | 5 | 7 | 31 | |
| GSE46452 | GLE1 | 2733 | 6 | 13 | 40 | |
| GSE47630 | GLE1 | 2733 | 3 | 16 | 21 | |
| GSE54993 | GLE1 | 2733 | 3 | 3 | 64 | |
| GSE54994 | GLE1 | 2733 | 11 | 8 | 34 | |
| GSE60625 | GLE1 | 2733 | 0 | 0 | 11 | |
| GSE74703 | GLE1 | 2733 | 5 | 5 | 26 | |
| GSE74704 | GLE1 | 2733 | 3 | 7 | 10 | |
| TCGA | GLE1 | 2733 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 101; Total Number of normals: 312.
Somatic mutations of GLE1:
Generating mutation plots.
Highly correlated genes for GLE1:
Showing top 20/643 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLE1 | KHNYN | 0.813666 | 3 | 0 | 3 |
| GLE1 | PTPRJ | 0.809701 | 3 | 0 | 3 |
| GLE1 | PPP1R3D | 0.79583 | 3 | 0 | 3 |
| GLE1 | ZNF343 | 0.776164 | 3 | 0 | 3 |
| GLE1 | SND1 | 0.775407 | 3 | 0 | 3 |
| GLE1 | CDC42SE2 | 0.769482 | 3 | 0 | 3 |
| GLE1 | SNRPD3 | 0.746725 | 3 | 0 | 3 |
| GLE1 | ABCB10 | 0.74632 | 3 | 0 | 3 |
| GLE1 | PLEKHM2 | 0.744449 | 3 | 0 | 3 |
| GLE1 | BPNT1 | 0.741227 | 3 | 0 | 3 |
| GLE1 | TNFRSF1A | 0.733543 | 3 | 0 | 3 |
| GLE1 | NACC1 | 0.73252 | 3 | 0 | 3 |
| GLE1 | C8orf76 | 0.728962 | 3 | 0 | 3 |
| GLE1 | ATXN1L | 0.724007 | 3 | 0 | 3 |
| GLE1 | COMMD2 | 0.717949 | 4 | 0 | 3 |
| GLE1 | FKBPL | 0.713994 | 3 | 0 | 3 |
| GLE1 | MCMBP | 0.713047 | 4 | 0 | 3 |
| GLE1 | COMMD7 | 0.712668 | 3 | 0 | 3 |
| GLE1 | PRRC2C | 0.706919 | 4 | 0 | 3 |
| GLE1 | FZR1 | 0.705799 | 4 | 0 | 3 |
For details and further investigation, click here
