KIDINS220

 

Full name: kinase D interacting substrate 220 Alias Symbol: ARMS
Type: protein-coding gene Cytoband: 2p25.1
Entrez ID: 57498 HGNC ID: HGNC:29508 Ensembl Gene: ENSG00000134313 OMIM ID: 615759
Drug and gene relationship at DGIdb
Screen Evidence:

 

KIDINS220 involved pathways:

KEGG pathway Description View
hsa04722Neurotrophin signaling pathway

 

Expression of KIDINS220:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIDINS220 57498 212163_at -0.0241 0.9594
GSE20347 KIDINS220 57498 212163_at 0.2283 0.0753
GSE23400 KIDINS220 57498 212163_at 0.1377 0.1352
GSE26886 KIDINS220 57498 212163_at -0.0133 0.9613
GSE29001 KIDINS220 57498 212163_at 0.1208 0.7000
GSE38129 KIDINS220 57498 212163_at 0.1597 0.1580
GSE45670 KIDINS220 57498 212163_at -0.0536 0.6813
GSE53622 KIDINS220 57498 104715 0.0557 0.4354
GSE53624 KIDINS220 57498 130354 -0.0337 0.6698
GSE63941 KIDINS220 57498 212163_at -1.4933 0.0011
GSE77861 KIDINS220 57498 212163_at 0.1801 0.3770
GSE97050 KIDINS220 57498 A_24_P7202 -0.0387 0.8782
SRP007169 KIDINS220 57498 RNAseq 0.5447 0.0662
SRP008496 KIDINS220 57498 RNAseq 0.6543 0.0021
SRP064894 KIDINS220 57498 RNAseq -0.2487 0.3779
SRP133303 KIDINS220 57498 RNAseq 0.1125 0.2022
SRP159526 KIDINS220 57498 RNAseq 0.2752 0.1481
SRP193095 KIDINS220 57498 RNAseq 0.0279 0.7393
SRP219564 KIDINS220 57498 RNAseq -0.0445 0.8418
TCGA KIDINS220 57498 RNAseq -0.0133 0.7600

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by KIDINS220 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIDINS220:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIDINS220 57498 10 2 18
GSE20123 KIDINS220 57498 10 2 18
GSE43470 KIDINS220 57498 2 1 40
GSE46452 KIDINS220 57498 3 4 52
GSE47630 KIDINS220 57498 7 0 33
GSE54993 KIDINS220 57498 0 7 63
GSE54994 KIDINS220 57498 11 0 42
GSE60625 KIDINS220 57498 0 3 8
GSE74703 KIDINS220 57498 2 0 34
GSE74704 KIDINS220 57498 9 1 10
TCGA KIDINS220 57498 34 4 58

Total number of gains: 88; Total number of losses: 24; Total Number of normals: 376.  

 

Somatic mutations of KIDINS220:

 

Generating mutation plots.

 

Highly correlated genes for KIDINS220:

 

Showing top 20/540 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIDINS220EXOSC60.730686303
KIDINS220NDEL10.727161303
KIDINS220NAPG0.719222303
KIDINS220KBTBD60.714125403
KIDINS220DCTN60.7124303
KIDINS220WDR350.712211303
KIDINS220CHUK0.707373303
KIDINS220SIPA1L20.706313303
KIDINS220TRUB10.700136303
KIDINS220C16orf720.699698303
KIDINS220SLC35A10.6948303
KIDINS220HADHB0.693436403
KIDINS220TET10.686592303
KIDINS220IL13RA20.686249303
KIDINS220IPO80.685693303
KIDINS220ZSCAN290.684706303
KIDINS220FNIP20.683976403
KIDINS220ZFX0.678254404
KIDINS220CEP440.6776404
KIDINS220EIF2B40.677169303

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