| Full name: dynactin subunit 6 | Alias Symbol: WS-3 | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 10671 | HGNC ID: HGNC:16964 | Ensembl Gene: ENSG00000104671 | OMIM ID: 612963 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DCTN6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCTN6 | 10671 | 203261_at | -0.1089 | 0.8066 | |
| GSE20347 | DCTN6 | 10671 | 203261_at | 0.1191 | 0.5556 | |
| GSE23400 | DCTN6 | 10671 | 203261_at | 0.1325 | 0.1420 | |
| GSE26886 | DCTN6 | 10671 | 203261_at | 0.0985 | 0.6121 | |
| GSE29001 | DCTN6 | 10671 | 203261_at | -0.0211 | 0.9545 | |
| GSE38129 | DCTN6 | 10671 | 203261_at | -0.0925 | 0.5445 | |
| GSE45670 | DCTN6 | 10671 | 203261_at | 0.0196 | 0.9157 | |
| GSE53622 | DCTN6 | 10671 | 26419 | 0.0253 | 0.7474 | |
| GSE53624 | DCTN6 | 10671 | 26419 | -0.0703 | 0.3061 | |
| GSE63941 | DCTN6 | 10671 | 203261_at | -0.3231 | 0.3059 | |
| GSE77861 | DCTN6 | 10671 | 203261_at | 0.0285 | 0.9161 | |
| GSE97050 | DCTN6 | 10671 | A_23_P43049 | -0.2523 | 0.3020 | |
| SRP007169 | DCTN6 | 10671 | RNAseq | 0.2777 | 0.6257 | |
| SRP008496 | DCTN6 | 10671 | RNAseq | 0.3166 | 0.4062 | |
| SRP064894 | DCTN6 | 10671 | RNAseq | -0.1970 | 0.2533 | |
| SRP133303 | DCTN6 | 10671 | RNAseq | -0.2374 | 0.3074 | |
| SRP159526 | DCTN6 | 10671 | RNAseq | -0.4370 | 0.0085 | |
| SRP193095 | DCTN6 | 10671 | RNAseq | -0.1795 | 0.3086 | |
| SRP219564 | DCTN6 | 10671 | RNAseq | -0.5456 | 0.0951 | |
| TCGA | DCTN6 | 10671 | RNAseq | -0.0208 | 0.7289 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCTN6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCTN6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCTN6 | 10671 | 4 | 10 | 16 | |
| GSE20123 | DCTN6 | 10671 | 4 | 10 | 16 | |
| GSE43470 | DCTN6 | 10671 | 4 | 7 | 32 | |
| GSE46452 | DCTN6 | 10671 | 13 | 13 | 33 | |
| GSE47630 | DCTN6 | 10671 | 10 | 8 | 22 | |
| GSE54993 | DCTN6 | 10671 | 2 | 15 | 53 | |
| GSE54994 | DCTN6 | 10671 | 10 | 15 | 28 | |
| GSE60625 | DCTN6 | 10671 | 3 | 0 | 8 | |
| GSE74703 | DCTN6 | 10671 | 4 | 6 | 26 | |
| GSE74704 | DCTN6 | 10671 | 3 | 7 | 10 | |
| TCGA | DCTN6 | 10671 | 17 | 41 | 38 |
Total number of gains: 74; Total number of losses: 132; Total Number of normals: 282.
Somatic mutations of DCTN6:
Generating mutation plots.
Highly correlated genes for DCTN6:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCTN6 | SRR | 0.772895 | 3 | 0 | 3 |
| DCTN6 | ASCC3 | 0.749782 | 3 | 0 | 3 |
| DCTN6 | NFAT5 | 0.747121 | 3 | 0 | 3 |
| DCTN6 | MOB3B | 0.728099 | 3 | 0 | 3 |
| DCTN6 | COX11 | 0.724996 | 3 | 0 | 3 |
| DCTN6 | MRPS35 | 0.719101 | 3 | 0 | 3 |
| DCTN6 | SLITRK6 | 0.716256 | 3 | 0 | 3 |
| DCTN6 | SS18 | 0.715831 | 3 | 0 | 3 |
| DCTN6 | KIDINS220 | 0.7124 | 3 | 0 | 3 |
| DCTN6 | ICAM1 | 0.69806 | 3 | 0 | 3 |
| DCTN6 | GRIK2 | 0.697798 | 3 | 0 | 3 |
| DCTN6 | LSM1 | 0.689082 | 5 | 0 | 5 |
| DCTN6 | TPRKB | 0.688887 | 3 | 0 | 3 |
| DCTN6 | ARL5B | 0.683259 | 3 | 0 | 3 |
| DCTN6 | NAE1 | 0.682895 | 3 | 0 | 3 |
| DCTN6 | PRKAG1 | 0.682084 | 3 | 0 | 3 |
| DCTN6 | CCT5 | 0.681602 | 3 | 0 | 3 |
| DCTN6 | POLR2G | 0.679892 | 3 | 0 | 3 |
| DCTN6 | PPP2CB | 0.667547 | 10 | 0 | 8 |
| DCTN6 | CXCL3 | 0.667107 | 3 | 0 | 3 |
For details and further investigation, click here
