| Full name: TAO kinase 2 | Alias Symbol: TAO1|KIAA0881|PSK|PSK1|TAO2|MAP3K17 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 9344 | HGNC ID: HGNC:16835 | Ensembl Gene: ENSG00000149930 | OMIM ID: 613199 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAOK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAOK2 | 9344 | 204878_s_at | 0.0564 | 0.8656 | |
| GSE20347 | TAOK2 | 9344 | 204878_s_at | -0.0514 | 0.6129 | |
| GSE23400 | TAOK2 | 9344 | 204986_s_at | -0.0213 | 0.5425 | |
| GSE26886 | TAOK2 | 9344 | 204878_s_at | 0.3181 | 0.0429 | |
| GSE29001 | TAOK2 | 9344 | 204986_s_at | -0.0704 | 0.7745 | |
| GSE38129 | TAOK2 | 9344 | 204878_s_at | -0.1191 | 0.1296 | |
| GSE45670 | TAOK2 | 9344 | 204878_s_at | 0.0115 | 0.9463 | |
| GSE53622 | TAOK2 | 9344 | 96808 | 0.2300 | 0.0000 | |
| GSE53624 | TAOK2 | 9344 | 96808 | 0.3050 | 0.0000 | |
| GSE63941 | TAOK2 | 9344 | 204878_s_at | 0.0788 | 0.7255 | |
| GSE77861 | TAOK2 | 9344 | 204878_s_at | -0.0127 | 0.9700 | |
| GSE97050 | TAOK2 | 9344 | A_33_P3346098 | 0.1657 | 0.4368 | |
| SRP007169 | TAOK2 | 9344 | RNAseq | -0.4683 | 0.2180 | |
| SRP008496 | TAOK2 | 9344 | RNAseq | -0.2969 | 0.1768 | |
| SRP064894 | TAOK2 | 9344 | RNAseq | 0.3092 | 0.0100 | |
| SRP133303 | TAOK2 | 9344 | RNAseq | 0.1709 | 0.2721 | |
| SRP159526 | TAOK2 | 9344 | RNAseq | -0.0126 | 0.9528 | |
| SRP193095 | TAOK2 | 9344 | RNAseq | 0.1460 | 0.1095 | |
| SRP219564 | TAOK2 | 9344 | RNAseq | 0.0403 | 0.8375 | |
| TCGA | TAOK2 | 9344 | RNAseq | -0.1435 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAOK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAOK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAOK2 | 9344 | 5 | 5 | 20 | |
| GSE20123 | TAOK2 | 9344 | 5 | 4 | 21 | |
| GSE43470 | TAOK2 | 9344 | 3 | 3 | 37 | |
| GSE46452 | TAOK2 | 9344 | 38 | 1 | 20 | |
| GSE47630 | TAOK2 | 9344 | 11 | 7 | 22 | |
| GSE54993 | TAOK2 | 9344 | 3 | 5 | 62 | |
| GSE54994 | TAOK2 | 9344 | 5 | 9 | 39 | |
| GSE60625 | TAOK2 | 9344 | 4 | 0 | 7 | |
| GSE74703 | TAOK2 | 9344 | 3 | 2 | 31 | |
| GSE74704 | TAOK2 | 9344 | 3 | 2 | 15 | |
| TCGA | TAOK2 | 9344 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of TAOK2:
Generating mutation plots.
Highly correlated genes for TAOK2:
Showing top 20/477 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAOK2 | SSH3 | 0.784897 | 4 | 0 | 4 |
| TAOK2 | DGCR9 | 0.746758 | 3 | 0 | 3 |
| TAOK2 | OPTC | 0.73545 | 3 | 0 | 3 |
| TAOK2 | NHLH1 | 0.735331 | 3 | 0 | 3 |
| TAOK2 | KIFC2 | 0.727953 | 7 | 0 | 7 |
| TAOK2 | REG3A | 0.719296 | 4 | 0 | 4 |
| TAOK2 | TOR2A | 0.710714 | 3 | 0 | 3 |
| TAOK2 | MAPK8IP2 | 0.710135 | 5 | 0 | 4 |
| TAOK2 | LIPE | 0.69995 | 5 | 0 | 5 |
| TAOK2 | RASL10B | 0.696946 | 5 | 0 | 4 |
| TAOK2 | NPPB | 0.693835 | 3 | 0 | 3 |
| TAOK2 | C10orf91 | 0.693091 | 3 | 0 | 3 |
| TAOK2 | RIMS4 | 0.6902 | 4 | 0 | 4 |
| TAOK2 | TRIM31 | 0.687959 | 3 | 0 | 3 |
| TAOK2 | SP8 | 0.686746 | 5 | 0 | 5 |
| TAOK2 | PTK2B | 0.684989 | 3 | 0 | 3 |
| TAOK2 | SLC6A13 | 0.684091 | 4 | 0 | 3 |
| TAOK2 | DNAL4 | 0.681044 | 3 | 0 | 3 |
| TAOK2 | NCKAP5L | 0.680731 | 3 | 0 | 3 |
| TAOK2 | MDFI | 0.678989 | 5 | 0 | 5 |
For details and further investigation, click here
