SALL4

 

Full name: spalt like transcription factor 4 Alias Symbol: dJ1112F19.1|ZNF797
Type: protein-coding gene Cytoband: 20q13.2
Entrez ID: 57167 HGNC ID: HGNC:15924 Ensembl Gene: ENSG00000101115 OMIM ID: 607343
Drug and gene relationship at DGIdb

 

Expression of SALL4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SALL4 57167 229661_at 0.8142 0.0676
GSE26886 SALL4 57167 229661_at 0.4422 0.0008
GSE45670 SALL4 57167 229661_at 0.5570 0.0006
GSE53622 SALL4 57167 107626 1.7665 0.0000
GSE53624 SALL4 57167 107626 2.4928 0.0000
GSE63941 SALL4 57167 229661_at 1.1847 0.1198
GSE77861 SALL4 57167 229661_at 0.3447 0.0889
GSE97050 SALL4 57167 A_23_P109072 0.5410 0.1733
SRP007169 SALL4 57167 RNAseq 4.3308 0.0029
SRP064894 SALL4 57167 RNAseq 2.5685 0.0000
SRP133303 SALL4 57167 RNAseq 2.1387 0.0000
SRP159526 SALL4 57167 RNAseq 3.5662 0.0000
SRP219564 SALL4 57167 RNAseq 3.2557 0.0000
TCGA SALL4 57167 RNAseq 2.3978 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  


 

Survival by SALL4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SALL4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SALL4 57167 16 2 12
GSE20123 SALL4 57167 16 2 12
GSE43470 SALL4 57167 13 0 30
GSE46452 SALL4 57167 29 0 30
GSE47630 SALL4 57167 24 1 15
GSE54993 SALL4 57167 0 17 53
GSE54994 SALL4 57167 27 0 26
GSE60625 SALL4 57167 0 0 11
GSE74703 SALL4 57167 10 0 26
GSE74704 SALL4 57167 12 0 8
TCGA SALL4 57167 45 3 48

Total number of gains: 192; Total number of losses: 25; Total Number of normals: 271.  


 

Somatic mutations of SALL4:

 

Generating mutation plots.

 

Highly correlated genes for SALL4:

 

Showing top 20/713 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SALL4GPRIN10.779995606
SALL4DNMT3B0.776536707
SALL4PTK70.774615606
SALL4KIF190.756175303
SALL4C2orf810.755607303
SALL4HOXD100.746271808
SALL4COL27A10.736133707
SALL4HOXD110.733976707
SALL4INHBA0.733837606
SALL4LOXL20.732712606
SALL4B4GALNT10.732252404
SALL4MMP10.72924606
SALL4RUNX1-IT10.721216404
SALL4RFX80.720425303
SALL4PLAU0.720167606
SALL4MMP110.718433605
SALL4MFAP20.718356706
SALL4COL5A10.714495705
SALL4COL10A10.713837706
SALL4NPM20.713764404

For details and further investigation, click here