| Full name: TBC1 domain family member 23 | Alias Symbol: FLJ11046 | ||
| Type: protein-coding gene | Cytoband: 3q12.1-q12.2 | ||
| Entrez ID: 55773 | HGNC ID: HGNC:25622 | Ensembl Gene: ENSG00000036054 | OMIM ID: 617687 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D23 | 55773 | 225121_at | 0.0659 | 0.8906 | |
| GSE26886 | TBC1D23 | 55773 | 225121_at | -0.4478 | 0.0067 | |
| GSE45670 | TBC1D23 | 55773 | 225121_at | 0.0922 | 0.4745 | |
| GSE53622 | TBC1D23 | 55773 | 69230 | -0.0716 | 0.3515 | |
| GSE53624 | TBC1D23 | 55773 | 69230 | 0.0193 | 0.7994 | |
| GSE63941 | TBC1D23 | 55773 | 225121_at | -1.0752 | 0.0432 | |
| GSE77861 | TBC1D23 | 55773 | 225121_at | -0.2933 | 0.5630 | |
| GSE97050 | TBC1D23 | 55773 | A_23_P212728 | 0.2449 | 0.4271 | |
| SRP007169 | TBC1D23 | 55773 | RNAseq | -0.6765 | 0.1220 | |
| SRP008496 | TBC1D23 | 55773 | RNAseq | -0.4964 | 0.0481 | |
| SRP064894 | TBC1D23 | 55773 | RNAseq | -0.2015 | 0.3464 | |
| SRP133303 | TBC1D23 | 55773 | RNAseq | 0.2262 | 0.1783 | |
| SRP159526 | TBC1D23 | 55773 | RNAseq | -0.2198 | 0.3261 | |
| SRP193095 | TBC1D23 | 55773 | RNAseq | -0.2012 | 0.1295 | |
| SRP219564 | TBC1D23 | 55773 | RNAseq | -0.2421 | 0.4559 | |
| TCGA | TBC1D23 | 55773 | RNAseq | 0.0255 | 0.6136 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TBC1D23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D23 | 55773 | 17 | 1 | 12 | |
| GSE20123 | TBC1D23 | 55773 | 16 | 1 | 13 | |
| GSE43470 | TBC1D23 | 55773 | 19 | 1 | 23 | |
| GSE46452 | TBC1D23 | 55773 | 12 | 6 | 41 | |
| GSE47630 | TBC1D23 | 55773 | 16 | 6 | 18 | |
| GSE54993 | TBC1D23 | 55773 | 2 | 5 | 63 | |
| GSE54994 | TBC1D23 | 55773 | 27 | 5 | 21 | |
| GSE60625 | TBC1D23 | 55773 | 0 | 6 | 5 | |
| GSE74703 | TBC1D23 | 55773 | 15 | 1 | 20 | |
| GSE74704 | TBC1D23 | 55773 | 13 | 1 | 6 | |
| TCGA | TBC1D23 | 55773 | 48 | 10 | 38 |
Total number of gains: 185; Total number of losses: 43; Total Number of normals: 260.
Somatic mutations of TBC1D23:
Generating mutation plots.
Highly correlated genes for TBC1D23:
Showing top 20/286 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D23 | PPP2R5E | 0.805489 | 3 | 0 | 3 |
| TBC1D23 | CUL3 | 0.782534 | 3 | 0 | 3 |
| TBC1D23 | MTPN | 0.771486 | 4 | 0 | 4 |
| TBC1D23 | MRC2 | 0.769276 | 3 | 0 | 3 |
| TBC1D23 | CSNK1A1 | 0.758251 | 4 | 0 | 4 |
| TBC1D23 | NCK2 | 0.748779 | 3 | 0 | 3 |
| TBC1D23 | LSM14B | 0.744601 | 3 | 0 | 3 |
| TBC1D23 | MAP4K5 | 0.742931 | 3 | 0 | 3 |
| TBC1D23 | UFSP2 | 0.7417 | 3 | 0 | 3 |
| TBC1D23 | ZMPSTE24 | 0.737805 | 4 | 0 | 4 |
| TBC1D23 | B4GALT5 | 0.736389 | 4 | 0 | 4 |
| TBC1D23 | FNIP1 | 0.729606 | 3 | 0 | 3 |
| TBC1D23 | HSPA4L | 0.722668 | 3 | 0 | 3 |
| TBC1D23 | LCMT1 | 0.721812 | 3 | 0 | 3 |
| TBC1D23 | FBXW11 | 0.721121 | 3 | 0 | 3 |
| TBC1D23 | SPIC | 0.719575 | 3 | 0 | 3 |
| TBC1D23 | SPPL3 | 0.718058 | 4 | 0 | 4 |
| TBC1D23 | ACVR2A | 0.717953 | 3 | 0 | 3 |
| TBC1D23 | OPTN | 0.71382 | 3 | 0 | 3 |
| TBC1D23 | NCOA3 | 0.712207 | 3 | 0 | 3 |
For details and further investigation, click here
