| Full name: SPT2 chromatin protein domain containing 1 | Alias Symbol: FLJ39441|DKFZp686I068|Spt2 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 144108 | HGNC ID: HGNC:26818 | Ensembl Gene: ENSG00000179119 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SPTY2D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPTY2D1 | 144108 | 229594_at | -0.0557 | 0.8807 | |
| GSE26886 | SPTY2D1 | 144108 | 229594_at | -0.1843 | 0.4154 | |
| GSE45670 | SPTY2D1 | 144108 | 229594_at | 0.0103 | 0.9593 | |
| GSE53622 | SPTY2D1 | 144108 | 18683 | -0.3508 | 0.0000 | |
| GSE53624 | SPTY2D1 | 144108 | 18683 | -0.3641 | 0.0000 | |
| GSE63941 | SPTY2D1 | 144108 | 229594_at | -0.4366 | 0.2387 | |
| GSE77861 | SPTY2D1 | 144108 | 229594_at | -0.0334 | 0.9413 | |
| GSE97050 | SPTY2D1 | 144108 | A_23_P328237 | -0.0170 | 0.9481 | |
| SRP007169 | SPTY2D1 | 144108 | RNAseq | 0.2100 | 0.6426 | |
| SRP008496 | SPTY2D1 | 144108 | RNAseq | 0.3210 | 0.2933 | |
| SRP064894 | SPTY2D1 | 144108 | RNAseq | -0.2675 | 0.1877 | |
| SRP133303 | SPTY2D1 | 144108 | RNAseq | 0.2597 | 0.1709 | |
| SRP159526 | SPTY2D1 | 144108 | RNAseq | -0.5682 | 0.0522 | |
| SRP193095 | SPTY2D1 | 144108 | RNAseq | -0.2806 | 0.0019 | |
| SRP219564 | SPTY2D1 | 144108 | RNAseq | -0.2810 | 0.2882 | |
| TCGA | SPTY2D1 | 144108 | RNAseq | -0.0566 | 0.2451 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPTY2D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPTY2D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPTY2D1 | 144108 | 0 | 10 | 20 | |
| GSE20123 | SPTY2D1 | 144108 | 0 | 10 | 20 | |
| GSE43470 | SPTY2D1 | 144108 | 1 | 5 | 37 | |
| GSE46452 | SPTY2D1 | 144108 | 7 | 5 | 47 | |
| GSE47630 | SPTY2D1 | 144108 | 3 | 10 | 27 | |
| GSE54993 | SPTY2D1 | 144108 | 3 | 0 | 67 | |
| GSE54994 | SPTY2D1 | 144108 | 2 | 13 | 38 | |
| GSE60625 | SPTY2D1 | 144108 | 0 | 0 | 11 | |
| GSE74703 | SPTY2D1 | 144108 | 1 | 3 | 32 | |
| GSE74704 | SPTY2D1 | 144108 | 0 | 9 | 11 | |
| TCGA | SPTY2D1 | 144108 | 11 | 29 | 56 |
Total number of gains: 28; Total number of losses: 94; Total Number of normals: 366.
Somatic mutations of SPTY2D1:
Generating mutation plots.
Highly correlated genes for SPTY2D1:
Showing top 20/272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPTY2D1 | KIN | 0.790766 | 3 | 0 | 3 |
| SPTY2D1 | MFN1 | 0.744217 | 3 | 0 | 3 |
| SPTY2D1 | B4GALT5 | 0.730036 | 4 | 0 | 4 |
| SPTY2D1 | RMND1 | 0.727441 | 3 | 0 | 3 |
| SPTY2D1 | TMEM150C | 0.721727 | 3 | 0 | 3 |
| SPTY2D1 | MORN2 | 0.720186 | 3 | 0 | 3 |
| SPTY2D1 | MRPL30 | 0.718974 | 3 | 0 | 3 |
| SPTY2D1 | ZMYM2 | 0.717939 | 3 | 0 | 3 |
| SPTY2D1 | COPS2 | 0.696299 | 3 | 0 | 3 |
| SPTY2D1 | PCM1 | 0.69461 | 3 | 0 | 3 |
| SPTY2D1 | NBR1 | 0.691756 | 3 | 0 | 3 |
| SPTY2D1 | ARHGAP9 | 0.681465 | 3 | 0 | 3 |
| SPTY2D1 | ZNF267 | 0.676867 | 3 | 0 | 3 |
| SPTY2D1 | DNAJC24 | 0.675675 | 5 | 0 | 4 |
| SPTY2D1 | TTC37 | 0.675236 | 3 | 0 | 3 |
| SPTY2D1 | NUDT15 | 0.674707 | 3 | 0 | 3 |
| SPTY2D1 | SGPP2 | 0.671305 | 3 | 0 | 3 |
| SPTY2D1 | SERPINB9 | 0.668198 | 4 | 0 | 3 |
| SPTY2D1 | CRNKL1 | 0.664227 | 4 | 0 | 3 |
| SPTY2D1 | USP47 | 0.663822 | 5 | 0 | 5 |
For details and further investigation, click here
