| Full name: retinoic acid induced 1 | Alias Symbol: DKFZP434A139|SMS|KIAA1820|MGC12824 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 10743 | HGNC ID: HGNC:9834 | Ensembl Gene: ENSG00000108557 | OMIM ID: 607642 |
| Drug and gene relationship at DGIdb | |||
Expression of RAI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAI1 | 10743 | 226143_at | 0.3188 | 0.4151 | |
| GSE20347 | RAI1 | 10743 | 219830_at | -0.0870 | 0.4125 | |
| GSE23400 | RAI1 | 10743 | 219830_at | -0.2723 | 0.0000 | |
| GSE26886 | RAI1 | 10743 | 226143_at | 1.4138 | 0.0000 | |
| GSE29001 | RAI1 | 10743 | 219830_at | -0.0467 | 0.7894 | |
| GSE38129 | RAI1 | 10743 | 219830_at | -0.0985 | 0.3862 | |
| GSE45670 | RAI1 | 10743 | 226143_at | 0.6972 | 0.0001 | |
| GSE53622 | RAI1 | 10743 | 12837 | 0.7501 | 0.0000 | |
| GSE53624 | RAI1 | 10743 | 12837 | 0.9390 | 0.0000 | |
| GSE63941 | RAI1 | 10743 | 226143_at | 0.6250 | 0.2800 | |
| GSE77861 | RAI1 | 10743 | 226143_at | 1.0508 | 0.0121 | |
| GSE97050 | RAI1 | 10743 | A_33_P3320503 | 0.3226 | 0.2942 | |
| SRP007169 | RAI1 | 10743 | RNAseq | 1.1376 | 0.0290 | |
| SRP008496 | RAI1 | 10743 | RNAseq | 0.7269 | 0.0466 | |
| SRP064894 | RAI1 | 10743 | RNAseq | 1.0474 | 0.0004 | |
| SRP133303 | RAI1 | 10743 | RNAseq | 0.7001 | 0.0000 | |
| SRP159526 | RAI1 | 10743 | RNAseq | 1.0098 | 0.0000 | |
| SRP193095 | RAI1 | 10743 | RNAseq | 0.8427 | 0.0000 | |
| SRP219564 | RAI1 | 10743 | RNAseq | 0.5621 | 0.0307 | |
| TCGA | RAI1 | 10743 | RNAseq | 0.0566 | 0.2385 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RAI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAI1 | 10743 | 3 | 3 | 24 | |
| GSE20123 | RAI1 | 10743 | 3 | 4 | 23 | |
| GSE43470 | RAI1 | 10743 | 1 | 5 | 37 | |
| GSE46452 | RAI1 | 10743 | 34 | 1 | 24 | |
| GSE47630 | RAI1 | 10743 | 7 | 1 | 32 | |
| GSE54993 | RAI1 | 10743 | 3 | 3 | 64 | |
| GSE54994 | RAI1 | 10743 | 6 | 6 | 41 | |
| GSE60625 | RAI1 | 10743 | 4 | 0 | 7 | |
| GSE74703 | RAI1 | 10743 | 1 | 2 | 33 | |
| GSE74704 | RAI1 | 10743 | 2 | 1 | 17 | |
| TCGA | RAI1 | 10743 | 18 | 23 | 55 |
Total number of gains: 82; Total number of losses: 49; Total Number of normals: 357.
Somatic mutations of RAI1:
Generating mutation plots.
Highly correlated genes for RAI1:
Showing top 20/734 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAI1 | FBRSL1 | 0.779884 | 4 | 0 | 4 |
| RAI1 | TMEM132A | 0.755818 | 3 | 0 | 3 |
| RAI1 | FMNL1 | 0.743002 | 3 | 0 | 3 |
| RAI1 | JAK3 | 0.741958 | 4 | 0 | 4 |
| RAI1 | SLC5A5 | 0.731056 | 5 | 0 | 5 |
| RAI1 | XPR1 | 0.725851 | 6 | 0 | 6 |
| RAI1 | GPR52 | 0.725178 | 4 | 0 | 3 |
| RAI1 | TNFAIP8L1 | 0.722626 | 5 | 0 | 4 |
| RAI1 | KIR2DS3 | 0.718581 | 5 | 0 | 5 |
| RAI1 | AMBN | 0.717402 | 4 | 0 | 4 |
| RAI1 | CETN1 | 0.717284 | 4 | 0 | 4 |
| RAI1 | MTFP1 | 0.716495 | 5 | 0 | 5 |
| RAI1 | GJA8 | 0.71277 | 4 | 0 | 4 |
| RAI1 | SIPA1L3 | 0.707149 | 3 | 0 | 3 |
| RAI1 | CDCA2 | 0.704925 | 4 | 0 | 4 |
| RAI1 | SPINK2 | 0.704006 | 4 | 0 | 4 |
| RAI1 | OR10J1 | 0.703919 | 4 | 0 | 4 |
| RAI1 | CYP2D6 | 0.701956 | 5 | 0 | 5 |
| RAI1 | CMSS1 | 0.700578 | 6 | 0 | 6 |
| RAI1 | PSG9 | 0.699991 | 3 | 0 | 3 |
For details and further investigation, click here
