AKIRIN2

 

Full name: akirin 2 Alias Symbol: FLJ10342|dJ486L4.2
Type: protein-coding gene Cytoband: 6q15
Entrez ID: 55122 HGNC ID: HGNC:21407 Ensembl Gene: ENSG00000135334 OMIM ID: 615165
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of AKIRIN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AKIRIN2 55122 223145_s_at -0.2592 0.7033
GSE26886 AKIRIN2 55122 223145_s_at -0.9162 0.0000
GSE45670 AKIRIN2 55122 223145_s_at 0.1821 0.2087
GSE53622 AKIRIN2 55122 39375 -0.0655 0.3837
GSE53624 AKIRIN2 55122 39375 -0.3170 0.0000
GSE63941 AKIRIN2 55122 223145_s_at -0.4589 0.2642
GSE77861 AKIRIN2 55122 223145_s_at 0.0449 0.8816
GSE97050 AKIRIN2 55122 A_23_P428827 0.3421 0.2151
SRP007169 AKIRIN2 55122 RNAseq -0.0748 0.8441
SRP008496 AKIRIN2 55122 RNAseq -0.1858 0.4886
SRP064894 AKIRIN2 55122 RNAseq -0.2410 0.1146
SRP133303 AKIRIN2 55122 RNAseq 0.0134 0.9317
SRP159526 AKIRIN2 55122 RNAseq -0.1902 0.3841
SRP193095 AKIRIN2 55122 RNAseq -0.2595 0.0501
SRP219564 AKIRIN2 55122 RNAseq -0.2079 0.5052
TCGA AKIRIN2 55122 RNAseq 0.2047 0.0001

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by AKIRIN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of AKIRIN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AKIRIN2 55122 1 4 25
GSE20123 AKIRIN2 55122 1 3 26
GSE43470 AKIRIN2 55122 3 1 39
GSE46452 AKIRIN2 55122 2 11 46
GSE47630 AKIRIN2 55122 8 6 26
GSE54993 AKIRIN2 55122 3 2 65
GSE54994 AKIRIN2 55122 8 8 37
GSE60625 AKIRIN2 55122 0 1 10
GSE74703 AKIRIN2 55122 3 1 32
GSE74704 AKIRIN2 55122 0 2 18
TCGA AKIRIN2 55122 5 21 70

Total number of gains: 34; Total number of losses: 60; Total Number of normals: 394.  


 

Somatic mutations of AKIRIN2:

 

Generating mutation plots.

 

Highly correlated genes for AKIRIN2:

 

Showing top 20/198 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AKIRIN2SUCLG10.804281303
AKIRIN2CEPT10.800068303
AKIRIN2SLC12A60.783117303
AKIRIN2RAB8A0.733222303
AKIRIN2PDLIM20.729064303
AKIRIN2VAPA0.726995303
AKIRIN2SERPINB90.71848303
AKIRIN2RNGTT0.715368404
AKIRIN2CLK30.706674303
AKIRIN2CHMP1B0.704684303
AKIRIN2UBE2J10.699163303
AKIRIN2FAM162B0.696629303
AKIRIN2GANC0.687143403
AKIRIN2KLF140.685591303
AKIRIN2EIF4G10.684182303
AKIRIN2CHD90.682409303
AKIRIN2GSX20.677425303
AKIRIN2KCNJ50.674505303
AKIRIN2NPC10.674095504
AKIRIN2KALRN0.662807403

For details and further investigation, click here