Full name: akirin 2 | Alias Symbol: FLJ10342|dJ486L4.2 | ||
Type: protein-coding gene | Cytoband: 6q15 | ||
Entrez ID: 55122 | HGNC ID: HGNC:21407 | Ensembl Gene: ENSG00000135334 | OMIM ID: 615165 |
Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AKIRIN2:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | AKIRIN2 | 55122 | 223145_s_at | -0.2592 | 0.7033 | |
GSE26886 | AKIRIN2 | 55122 | 223145_s_at | -0.9162 | 0.0000 | |
GSE45670 | AKIRIN2 | 55122 | 223145_s_at | 0.1821 | 0.2087 | |
GSE53622 | AKIRIN2 | 55122 | 39375 | -0.0655 | 0.3837 | |
GSE53624 | AKIRIN2 | 55122 | 39375 | -0.3170 | 0.0000 | |
GSE63941 | AKIRIN2 | 55122 | 223145_s_at | -0.4589 | 0.2642 | |
GSE77861 | AKIRIN2 | 55122 | 223145_s_at | 0.0449 | 0.8816 | |
GSE97050 | AKIRIN2 | 55122 | A_23_P428827 | 0.3421 | 0.2151 | |
SRP007169 | AKIRIN2 | 55122 | RNAseq | -0.0748 | 0.8441 | |
SRP008496 | AKIRIN2 | 55122 | RNAseq | -0.1858 | 0.4886 | |
SRP064894 | AKIRIN2 | 55122 | RNAseq | -0.2410 | 0.1146 | |
SRP133303 | AKIRIN2 | 55122 | RNAseq | 0.0134 | 0.9317 | |
SRP159526 | AKIRIN2 | 55122 | RNAseq | -0.1902 | 0.3841 | |
SRP193095 | AKIRIN2 | 55122 | RNAseq | -0.2595 | 0.0501 | |
SRP219564 | AKIRIN2 | 55122 | RNAseq | -0.2079 | 0.5052 | |
TCGA | AKIRIN2 | 55122 | RNAseq | 0.2047 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AKIRIN2 expression:
Note: Click image to view full size file.
Copy number change of AKIRIN2:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | AKIRIN2 | 55122 | 1 | 4 | 25 | |
GSE20123 | AKIRIN2 | 55122 | 1 | 3 | 26 | |
GSE43470 | AKIRIN2 | 55122 | 3 | 1 | 39 | |
GSE46452 | AKIRIN2 | 55122 | 2 | 11 | 46 | |
GSE47630 | AKIRIN2 | 55122 | 8 | 6 | 26 | |
GSE54993 | AKIRIN2 | 55122 | 3 | 2 | 65 | |
GSE54994 | AKIRIN2 | 55122 | 8 | 8 | 37 | |
GSE60625 | AKIRIN2 | 55122 | 0 | 1 | 10 | |
GSE74703 | AKIRIN2 | 55122 | 3 | 1 | 32 | |
GSE74704 | AKIRIN2 | 55122 | 0 | 2 | 18 | |
TCGA | AKIRIN2 | 55122 | 5 | 21 | 70 |
Total number of gains: 34; Total number of losses: 60; Total Number of normals: 394.
Somatic mutations of AKIRIN2:
Generating mutation plots.
Highly correlated genes for AKIRIN2:
Showing top 20/198 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
AKIRIN2 | SUCLG1 | 0.804281 | 3 | 0 | 3 |
AKIRIN2 | CEPT1 | 0.800068 | 3 | 0 | 3 |
AKIRIN2 | SLC12A6 | 0.783117 | 3 | 0 | 3 |
AKIRIN2 | RAB8A | 0.733222 | 3 | 0 | 3 |
AKIRIN2 | PDLIM2 | 0.729064 | 3 | 0 | 3 |
AKIRIN2 | VAPA | 0.726995 | 3 | 0 | 3 |
AKIRIN2 | SERPINB9 | 0.71848 | 3 | 0 | 3 |
AKIRIN2 | RNGTT | 0.715368 | 4 | 0 | 4 |
AKIRIN2 | CLK3 | 0.706674 | 3 | 0 | 3 |
AKIRIN2 | CHMP1B | 0.704684 | 3 | 0 | 3 |
AKIRIN2 | UBE2J1 | 0.699163 | 3 | 0 | 3 |
AKIRIN2 | FAM162B | 0.696629 | 3 | 0 | 3 |
AKIRIN2 | GANC | 0.687143 | 4 | 0 | 3 |
AKIRIN2 | KLF14 | 0.685591 | 3 | 0 | 3 |
AKIRIN2 | EIF4G1 | 0.684182 | 3 | 0 | 3 |
AKIRIN2 | CHD9 | 0.682409 | 3 | 0 | 3 |
AKIRIN2 | GSX2 | 0.677425 | 3 | 0 | 3 |
AKIRIN2 | KCNJ5 | 0.674505 | 3 | 0 | 3 |
AKIRIN2 | NPC1 | 0.674095 | 5 | 0 | 4 |
AKIRIN2 | KALRN | 0.662807 | 4 | 0 | 3 |
For details and further investigation, click here