| Full name: filamin binding LIM protein 1 | Alias Symbol: FBLP-1|CAL|migfilin | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 54751 | HGNC ID: HGNC:24686 | Ensembl Gene: ENSG00000162458 | OMIM ID: 607747 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FBLIM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBLIM1 | 54751 | 225258_at | 1.1623 | 0.0250 | |
| GSE26886 | FBLIM1 | 54751 | 225258_at | 1.3174 | 0.0000 | |
| GSE45670 | FBLIM1 | 54751 | 225258_at | 0.8141 | 0.0065 | |
| GSE53622 | FBLIM1 | 54751 | 79747 | 1.2447 | 0.0000 | |
| GSE53624 | FBLIM1 | 54751 | 79747 | 1.3335 | 0.0000 | |
| GSE63941 | FBLIM1 | 54751 | 225258_at | -0.6690 | 0.2339 | |
| GSE77861 | FBLIM1 | 54751 | 225258_at | 0.8230 | 0.0524 | |
| GSE97050 | FBLIM1 | 54751 | A_23_P337934 | 1.1208 | 0.0620 | |
| SRP007169 | FBLIM1 | 54751 | RNAseq | 1.3095 | 0.0015 | |
| SRP008496 | FBLIM1 | 54751 | RNAseq | 1.7736 | 0.0000 | |
| SRP064894 | FBLIM1 | 54751 | RNAseq | 1.2830 | 0.0000 | |
| SRP133303 | FBLIM1 | 54751 | RNAseq | 1.0294 | 0.0001 | |
| SRP159526 | FBLIM1 | 54751 | RNAseq | 0.6501 | 0.0586 | |
| SRP193095 | FBLIM1 | 54751 | RNAseq | 0.6738 | 0.0122 | |
| SRP219564 | FBLIM1 | 54751 | RNAseq | -0.1611 | 0.7074 | |
| TCGA | FBLIM1 | 54751 | RNAseq | 0.1057 | 0.1543 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by FBLIM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBLIM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBLIM1 | 54751 | 1 | 5 | 24 | |
| GSE20123 | FBLIM1 | 54751 | 1 | 4 | 25 | |
| GSE43470 | FBLIM1 | 54751 | 1 | 8 | 34 | |
| GSE46452 | FBLIM1 | 54751 | 7 | 1 | 51 | |
| GSE47630 | FBLIM1 | 54751 | 8 | 3 | 29 | |
| GSE54993 | FBLIM1 | 54751 | 3 | 1 | 66 | |
| GSE54994 | FBLIM1 | 54751 | 10 | 6 | 37 | |
| GSE60625 | FBLIM1 | 54751 | 0 | 0 | 11 | |
| GSE74703 | FBLIM1 | 54751 | 1 | 5 | 30 | |
| GSE74704 | FBLIM1 | 54751 | 1 | 0 | 19 | |
| TCGA | FBLIM1 | 54751 | 12 | 23 | 61 |
Total number of gains: 45; Total number of losses: 56; Total Number of normals: 387.
Somatic mutations of FBLIM1:
Generating mutation plots.
Highly correlated genes for FBLIM1:
Showing top 20/1542 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBLIM1 | MSN | 0.783016 | 7 | 0 | 6 |
| FBLIM1 | AGRN | 0.773791 | 7 | 0 | 7 |
| FBLIM1 | PLAU | 0.773557 | 8 | 0 | 7 |
| FBLIM1 | COL5A2 | 0.772813 | 7 | 0 | 7 |
| FBLIM1 | TUBA1B | 0.769594 | 4 | 0 | 4 |
| FBLIM1 | FNDC3B | 0.765608 | 7 | 0 | 7 |
| FBLIM1 | KLHL13 | 0.764706 | 3 | 0 | 3 |
| FBLIM1 | KLF7 | 0.763664 | 7 | 0 | 7 |
| FBLIM1 | ENAH | 0.762023 | 8 | 0 | 7 |
| FBLIM1 | ZNF114 | 0.760637 | 4 | 0 | 4 |
| FBLIM1 | COL5A1 | 0.760456 | 7 | 0 | 6 |
| FBLIM1 | LPCAT1 | 0.759441 | 7 | 0 | 7 |
| FBLIM1 | ITGA3 | 0.755746 | 8 | 0 | 7 |
| FBLIM1 | SLC2A3 | 0.755457 | 4 | 0 | 4 |
| FBLIM1 | PSPC1 | 0.755017 | 3 | 0 | 3 |
| FBLIM1 | TNFRSF12A | 0.754771 | 7 | 0 | 7 |
| FBLIM1 | GNG10 | 0.753759 | 3 | 0 | 3 |
| FBLIM1 | FAM89A | 0.753735 | 3 | 0 | 3 |
| FBLIM1 | KLF10 | 0.752941 | 4 | 0 | 4 |
| FBLIM1 | FHOD1 | 0.748982 | 7 | 0 | 7 |
For details and further investigation, click here
