| Full name: syntrophin alpha 1 | Alias Symbol: TACIP1|LQT12 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 6640 | HGNC ID: HGNC:11167 | Ensembl Gene: ENSG00000101400 | OMIM ID: 601017 |
| Drug and gene relationship at DGIdb | |||
Expression of SNTA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNTA1 | 6640 | 203516_at | 0.0502 | 0.9106 | |
| GSE20347 | SNTA1 | 6640 | 203516_at | -0.0158 | 0.9096 | |
| GSE23400 | SNTA1 | 6640 | 203516_at | -0.2381 | 0.0000 | |
| GSE26886 | SNTA1 | 6640 | 203516_at | 0.3823 | 0.0074 | |
| GSE29001 | SNTA1 | 6640 | 203516_at | -0.0988 | 0.5787 | |
| GSE38129 | SNTA1 | 6640 | 203516_at | -0.2441 | 0.0281 | |
| GSE45670 | SNTA1 | 6640 | 203516_at | -0.1779 | 0.0530 | |
| GSE53622 | SNTA1 | 6640 | 27253 | -0.5452 | 0.0000 | |
| GSE53624 | SNTA1 | 6640 | 27253 | -0.2812 | 0.0021 | |
| GSE63941 | SNTA1 | 6640 | 203516_at | 0.0401 | 0.9145 | |
| GSE77861 | SNTA1 | 6640 | 203516_at | 0.1989 | 0.2840 | |
| GSE97050 | SNTA1 | 6640 | A_24_P322709 | -0.1567 | 0.5183 | |
| SRP007169 | SNTA1 | 6640 | RNAseq | -0.9220 | 0.0924 | |
| SRP008496 | SNTA1 | 6640 | RNAseq | -0.4481 | 0.2665 | |
| SRP064894 | SNTA1 | 6640 | RNAseq | -0.0277 | 0.9409 | |
| SRP133303 | SNTA1 | 6640 | RNAseq | -0.1399 | 0.6113 | |
| SRP159526 | SNTA1 | 6640 | RNAseq | -0.6572 | 0.0621 | |
| SRP193095 | SNTA1 | 6640 | RNAseq | 0.0720 | 0.6813 | |
| SRP219564 | SNTA1 | 6640 | RNAseq | -0.4976 | 0.2439 | |
| TCGA | SNTA1 | 6640 | RNAseq | -0.3334 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNTA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNTA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNTA1 | 6640 | 15 | 0 | 15 | |
| GSE20123 | SNTA1 | 6640 | 15 | 0 | 15 | |
| GSE43470 | SNTA1 | 6640 | 12 | 0 | 31 | |
| GSE46452 | SNTA1 | 6640 | 29 | 0 | 30 | |
| GSE47630 | SNTA1 | 6640 | 24 | 1 | 15 | |
| GSE54993 | SNTA1 | 6640 | 0 | 19 | 51 | |
| GSE54994 | SNTA1 | 6640 | 26 | 1 | 26 | |
| GSE60625 | SNTA1 | 6640 | 0 | 0 | 11 | |
| GSE74703 | SNTA1 | 6640 | 11 | 0 | 25 | |
| GSE74704 | SNTA1 | 6640 | 10 | 0 | 10 | |
| TCGA | SNTA1 | 6640 | 50 | 1 | 45 |
Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.
Somatic mutations of SNTA1:
Generating mutation plots.
Highly correlated genes for SNTA1:
Showing top 20/394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNTA1 | NACC1 | 0.833806 | 3 | 0 | 3 |
| SNTA1 | ANKRD9 | 0.772543 | 3 | 0 | 3 |
| SNTA1 | DZIP1L | 0.768012 | 3 | 0 | 3 |
| SNTA1 | KLF7 | 0.767592 | 3 | 0 | 3 |
| SNTA1 | CAV1 | 0.750654 | 3 | 0 | 3 |
| SNTA1 | CAMKK1 | 0.747293 | 3 | 0 | 3 |
| SNTA1 | INO80E | 0.745443 | 3 | 0 | 3 |
| SNTA1 | TTC7B | 0.741767 | 4 | 0 | 4 |
| SNTA1 | MAST2 | 0.739211 | 3 | 0 | 3 |
| SNTA1 | NCDN | 0.738364 | 3 | 0 | 3 |
| SNTA1 | SF3A2 | 0.736399 | 5 | 0 | 5 |
| SNTA1 | ARHGEF11 | 0.734843 | 3 | 0 | 3 |
| SNTA1 | ZNF579 | 0.734792 | 3 | 0 | 3 |
| SNTA1 | A1BG | 0.732381 | 3 | 0 | 3 |
| SNTA1 | ACTN1 | 0.724559 | 4 | 0 | 4 |
| SNTA1 | B3GNT9 | 0.721221 | 4 | 0 | 4 |
| SNTA1 | DEGS1 | 0.714806 | 3 | 0 | 3 |
| SNTA1 | STC2 | 0.714793 | 3 | 0 | 3 |
| SNTA1 | SH2B1 | 0.71285 | 3 | 0 | 3 |
| SNTA1 | PRKAB2 | 0.708898 | 3 | 0 | 3 |
For details and further investigation, click here
