| Full name: cardiotrophin 1 | Alias Symbol: CT-1|CT1 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 1489 | HGNC ID: HGNC:2499 | Ensembl Gene: ENSG00000150281 | OMIM ID: 600435 |
| Drug and gene relationship at DGIdb | |||
CTF1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of CTF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTF1 | 1489 | 206813_at | -0.2603 | 0.5254 | |
| GSE20347 | CTF1 | 1489 | 206813_at | 0.1000 | 0.3153 | |
| GSE23400 | CTF1 | 1489 | 206813_at | 0.0104 | 0.8826 | |
| GSE26886 | CTF1 | 1489 | 206813_at | 0.3089 | 0.0532 | |
| GSE29001 | CTF1 | 1489 | 206813_at | -0.1614 | 0.6121 | |
| GSE38129 | CTF1 | 1489 | 206813_at | -0.1931 | 0.1481 | |
| GSE45670 | CTF1 | 1489 | 206813_at | -0.0008 | 0.9955 | |
| GSE53622 | CTF1 | 1489 | 91500 | -0.5077 | 0.0002 | |
| GSE53624 | CTF1 | 1489 | 91500 | -0.4083 | 0.0000 | |
| GSE63941 | CTF1 | 1489 | 206813_at | 0.2818 | 0.3106 | |
| GSE77861 | CTF1 | 1489 | 206813_at | 0.1769 | 0.3282 | |
| GSE97050 | CTF1 | 1489 | A_33_P3822503 | -0.1591 | 0.6804 | |
| SRP007169 | CTF1 | 1489 | RNAseq | -0.0891 | 0.8737 | |
| SRP064894 | CTF1 | 1489 | RNAseq | 0.1421 | 0.7183 | |
| SRP133303 | CTF1 | 1489 | RNAseq | -0.0212 | 0.9375 | |
| SRP159526 | CTF1 | 1489 | RNAseq | -0.5385 | 0.0420 | |
| SRP219564 | CTF1 | 1489 | RNAseq | -0.7854 | 0.2683 | |
| TCGA | CTF1 | 1489 | RNAseq | -0.2315 | 0.0868 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CTF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTF1 | 1489 | 5 | 5 | 20 | |
| GSE20123 | CTF1 | 1489 | 5 | 4 | 21 | |
| GSE43470 | CTF1 | 1489 | 3 | 3 | 37 | |
| GSE46452 | CTF1 | 1489 | 38 | 1 | 20 | |
| GSE47630 | CTF1 | 1489 | 11 | 7 | 22 | |
| GSE54993 | CTF1 | 1489 | 2 | 5 | 63 | |
| GSE54994 | CTF1 | 1489 | 5 | 9 | 39 | |
| GSE60625 | CTF1 | 1489 | 4 | 0 | 7 | |
| GSE74703 | CTF1 | 1489 | 3 | 2 | 31 | |
| GSE74704 | CTF1 | 1489 | 3 | 2 | 15 | |
| TCGA | CTF1 | 1489 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of CTF1:
Generating mutation plots.
Highly correlated genes for CTF1:
Showing top 20/612 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTF1 | MZF1 | 0.794132 | 3 | 0 | 3 |
| CTF1 | KLHL31 | 0.780849 | 3 | 0 | 3 |
| CTF1 | ANKRD9 | 0.764855 | 3 | 0 | 3 |
| CTF1 | GGN | 0.763206 | 3 | 0 | 3 |
| CTF1 | IMPDH1 | 0.761584 | 4 | 0 | 4 |
| CTF1 | B4GALT2 | 0.75342 | 4 | 0 | 4 |
| CTF1 | PRR12 | 0.751473 | 3 | 0 | 3 |
| CTF1 | BTBD2 | 0.75083 | 3 | 0 | 3 |
| CTF1 | SSBP3 | 0.744732 | 3 | 0 | 3 |
| CTF1 | PDK2 | 0.742751 | 4 | 0 | 3 |
| CTF1 | LENG8 | 0.742685 | 3 | 0 | 3 |
| CTF1 | KLF7 | 0.738964 | 3 | 0 | 3 |
| CTF1 | SAMD4B | 0.737733 | 4 | 0 | 3 |
| CTF1 | PHRF1 | 0.734931 | 3 | 0 | 3 |
| CTF1 | TPSG1 | 0.730577 | 3 | 0 | 3 |
| CTF1 | ZNF408 | 0.730388 | 4 | 0 | 4 |
| CTF1 | SPIRE1 | 0.729795 | 3 | 0 | 3 |
| CTF1 | PA2G4 | 0.728977 | 4 | 0 | 4 |
| CTF1 | EHMT2 | 0.727356 | 3 | 0 | 3 |
| CTF1 | MRC2 | 0.72116 | 3 | 0 | 3 |
For details and further investigation, click here
