| Full name: transforming acidic coiled-coil containing protein 2 | Alias Symbol: AZU-1 | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 10579 | HGNC ID: HGNC:11523 | Ensembl Gene: ENSG00000138162 | OMIM ID: 605302 |
| Drug and gene relationship at DGIdb | |||
Expression of TACC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TACC2 | 10579 | 202289_s_at | -0.6287 | 0.2142 | |
| GSE20347 | TACC2 | 10579 | 202289_s_at | -0.5205 | 0.0082 | |
| GSE23400 | TACC2 | 10579 | 211382_s_at | -0.5568 | 0.0000 | |
| GSE26886 | TACC2 | 10579 | 202289_s_at | 0.5591 | 0.0077 | |
| GSE29001 | TACC2 | 10579 | 202289_s_at | -0.7512 | 0.0210 | |
| GSE38129 | TACC2 | 10579 | 202289_s_at | -0.5012 | 0.0028 | |
| GSE45670 | TACC2 | 10579 | 202289_s_at | -0.3921 | 0.0268 | |
| GSE53622 | TACC2 | 10579 | 126999 | -0.8241 | 0.0000 | |
| GSE53624 | TACC2 | 10579 | 126999 | -0.9163 | 0.0000 | |
| GSE63941 | TACC2 | 10579 | 202289_s_at | 1.9330 | 0.0036 | |
| GSE77861 | TACC2 | 10579 | 202289_s_at | -0.0199 | 0.9404 | |
| GSE97050 | TACC2 | 10579 | A_23_P127186 | -0.7843 | 0.1556 | |
| SRP007169 | TACC2 | 10579 | RNAseq | 0.2419 | 0.5805 | |
| SRP008496 | TACC2 | 10579 | RNAseq | 0.0509 | 0.8720 | |
| SRP064894 | TACC2 | 10579 | RNAseq | -0.7305 | 0.0029 | |
| SRP133303 | TACC2 | 10579 | RNAseq | -0.8714 | 0.0000 | |
| SRP159526 | TACC2 | 10579 | RNAseq | -0.6477 | 0.2336 | |
| SRP193095 | TACC2 | 10579 | RNAseq | -0.3384 | 0.0483 | |
| SRP219564 | TACC2 | 10579 | RNAseq | -0.4175 | 0.3533 | |
| TCGA | TACC2 | 10579 | RNAseq | -0.2366 | 0.0041 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TACC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TACC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TACC2 | 10579 | 3 | 7 | 20 | |
| GSE20123 | TACC2 | 10579 | 3 | 7 | 20 | |
| GSE43470 | TACC2 | 10579 | 0 | 9 | 34 | |
| GSE46452 | TACC2 | 10579 | 0 | 11 | 48 | |
| GSE47630 | TACC2 | 10579 | 2 | 14 | 24 | |
| GSE54993 | TACC2 | 10579 | 8 | 1 | 61 | |
| GSE54994 | TACC2 | 10579 | 1 | 9 | 43 | |
| GSE60625 | TACC2 | 10579 | 0 | 0 | 11 | |
| GSE74703 | TACC2 | 10579 | 0 | 6 | 30 | |
| GSE74704 | TACC2 | 10579 | 2 | 2 | 16 | |
| TCGA | TACC2 | 10579 | 4 | 28 | 64 |
Total number of gains: 23; Total number of losses: 94; Total Number of normals: 371.
Somatic mutations of TACC2:
Generating mutation plots.
Highly correlated genes for TACC2:
Showing top 20/392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TACC2 | ZFYVE9 | 0.796979 | 3 | 0 | 3 |
| TACC2 | C6orf89 | 0.783157 | 3 | 0 | 3 |
| TACC2 | RBM33 | 0.751769 | 3 | 0 | 3 |
| TACC2 | IAH1 | 0.747032 | 3 | 0 | 3 |
| TACC2 | RNF144B | 0.738341 | 3 | 0 | 3 |
| TACC2 | CHADL | 0.730897 | 3 | 0 | 3 |
| TACC2 | ZNF398 | 0.717414 | 4 | 0 | 3 |
| TACC2 | PEX14 | 0.714849 | 3 | 0 | 3 |
| TACC2 | KAT5 | 0.714447 | 4 | 0 | 3 |
| TACC2 | GDPD1 | 0.712628 | 3 | 0 | 3 |
| TACC2 | ZNF394 | 0.710654 | 5 | 0 | 4 |
| TACC2 | KLHL23 | 0.710485 | 3 | 0 | 3 |
| TACC2 | PPM1L | 0.699585 | 4 | 0 | 3 |
| TACC2 | PNKD | 0.698987 | 4 | 0 | 3 |
| TACC2 | BCAS2 | 0.698276 | 3 | 0 | 3 |
| TACC2 | TIGD1 | 0.689794 | 3 | 0 | 3 |
| TACC2 | TSTD1 | 0.684924 | 4 | 0 | 4 |
| TACC2 | THAP4 | 0.683312 | 4 | 0 | 4 |
| TACC2 | KCNB1 | 0.679413 | 4 | 0 | 4 |
| TACC2 | VPS29 | 0.676947 | 4 | 0 | 4 |
For details and further investigation, click here
