| Full name: kelch like family member 42 | Alias Symbol: KIAA1340|Ctb9 | ||
| Type: protein-coding gene | Cytoband: 12p11.22 | ||
| Entrez ID: 57542 | HGNC ID: HGNC:29252 | Ensembl Gene: ENSG00000087448 | OMIM ID: |
Expression of KLHL42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL42 | 57542 | 225732_at | -0.1903 | 0.8368 | |
| GSE26886 | KLHL42 | 57542 | 225961_at | 0.8573 | 0.0272 | |
| GSE45670 | KLHL42 | 57542 | 225732_at | -0.2827 | 0.3692 | |
| GSE53622 | KLHL42 | 57542 | 129779 | -0.0640 | 0.6314 | |
| GSE53624 | KLHL42 | 57542 | 129779 | 0.3858 | 0.0000 | |
| GSE63941 | KLHL42 | 57542 | 225732_at | -0.7933 | 0.2085 | |
| GSE77861 | KLHL42 | 57542 | 225732_at | 1.6823 | 0.0013 | |
| SRP007169 | KLHL42 | 57542 | RNAseq | 2.7463 | 0.0000 | |
| SRP008496 | KLHL42 | 57542 | RNAseq | 3.3274 | 0.0000 | |
| SRP064894 | KLHL42 | 57542 | RNAseq | 0.1742 | 0.4274 | |
| SRP133303 | KLHL42 | 57542 | RNAseq | 0.3896 | 0.0570 | |
| SRP159526 | KLHL42 | 57542 | RNAseq | 0.6039 | 0.0023 | |
| SRP193095 | KLHL42 | 57542 | RNAseq | 1.0048 | 0.0000 | |
| SRP219564 | KLHL42 | 57542 | RNAseq | -0.1269 | 0.8009 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by KLHL42 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KLHL42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL42 | 57542 | 11 | 1 | 18 | |
| GSE20123 | KLHL42 | 57542 | 11 | 1 | 18 | |
| GSE43470 | KLHL42 | 57542 | 10 | 4 | 29 | |
| GSE46452 | KLHL42 | 57542 | 10 | 1 | 48 | |
| GSE47630 | KLHL42 | 57542 | 13 | 0 | 27 | |
| GSE54993 | KLHL42 | 57542 | 0 | 9 | 61 | |
| GSE54994 | KLHL42 | 57542 | 12 | 2 | 39 | |
| GSE60625 | KLHL42 | 57542 | 0 | 1 | 10 | |
| GSE74703 | KLHL42 | 57542 | 9 | 3 | 24 | |
| GSE74704 | KLHL42 | 57542 | 6 | 1 | 13 | |
| TCGA | KLHL42 | 57542 | 44 | 6 | 46 |
Total number of gains: 126; Total number of losses: 29; Total Number of normals: 333.
Somatic mutations of KLHL42:
Generating mutation plots.
Highly correlated genes for KLHL42:
Showing top 20/434 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL42 | AMMECR1L | 0.790982 | 3 | 0 | 3 |
| KLHL42 | MCAM | 0.722517 | 3 | 0 | 3 |
| KLHL42 | DNAJC10 | 0.722463 | 4 | 0 | 3 |
| KLHL42 | SACS | 0.717048 | 6 | 0 | 6 |
| KLHL42 | ATP11C | 0.704695 | 4 | 0 | 4 |
| KLHL42 | ITPKB | 0.704078 | 6 | 0 | 6 |
| KLHL42 | KLHL5 | 0.699326 | 6 | 0 | 6 |
| KLHL42 | CD99L2 | 0.697049 | 5 | 0 | 5 |
| KLHL42 | FGF12 | 0.694341 | 3 | 0 | 3 |
| KLHL42 | BCL2L13 | 0.685382 | 3 | 0 | 3 |
| KLHL42 | TUBB2B | 0.684717 | 3 | 0 | 3 |
| KLHL42 | ZDHHC4 | 0.682855 | 3 | 0 | 3 |
| KLHL42 | MAP1B | 0.679102 | 7 | 0 | 6 |
| KLHL42 | IWS1 | 0.678008 | 4 | 0 | 3 |
| KLHL42 | AKT3 | 0.676704 | 5 | 0 | 4 |
| KLHL42 | ANKRD40 | 0.673108 | 6 | 0 | 6 |
| KLHL42 | ATP2B4 | 0.671509 | 5 | 0 | 4 |
| KLHL42 | LRP12 | 0.670666 | 4 | 0 | 3 |
| KLHL42 | MAGI2 | 0.670636 | 4 | 0 | 4 |
| KLHL42 | STON1 | 0.670634 | 6 | 0 | 5 |
For details and further investigation, click here
