| Full name: zinc finger DHHC-type containing 4 | Alias Symbol: FLJ10479|ZNF374 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 55146 | HGNC ID: HGNC:18471 | Ensembl Gene: ENSG00000136247 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC4 | 55146 | 220261_s_at | -0.0129 | 0.9906 | |
| GSE20347 | ZDHHC4 | 55146 | 220261_s_at | 0.5388 | 0.0493 | |
| GSE23400 | ZDHHC4 | 55146 | 220261_s_at | 0.6088 | 0.0000 | |
| GSE26886 | ZDHHC4 | 55146 | 220261_s_at | 0.5805 | 0.1153 | |
| GSE29001 | ZDHHC4 | 55146 | 220261_s_at | 0.6279 | 0.2136 | |
| GSE38129 | ZDHHC4 | 55146 | 220261_s_at | 0.5319 | 0.0353 | |
| GSE45670 | ZDHHC4 | 55146 | 220261_s_at | 0.2408 | 0.3972 | |
| GSE63941 | ZDHHC4 | 55146 | 220261_s_at | 0.1634 | 0.6908 | |
| GSE77861 | ZDHHC4 | 55146 | 220261_s_at | 0.6878 | 0.0504 | |
| GSE97050 | ZDHHC4 | 55146 | A_23_P157147 | 0.2811 | 0.3181 | |
| SRP007169 | ZDHHC4 | 55146 | RNAseq | 0.6818 | 0.0742 | |
| SRP008496 | ZDHHC4 | 55146 | RNAseq | 0.6222 | 0.0328 | |
| SRP064894 | ZDHHC4 | 55146 | RNAseq | 0.4655 | 0.0718 | |
| SRP133303 | ZDHHC4 | 55146 | RNAseq | 0.6452 | 0.0000 | |
| SRP159526 | ZDHHC4 | 55146 | RNAseq | 0.5874 | 0.0006 | |
| SRP193095 | ZDHHC4 | 55146 | RNAseq | 0.4651 | 0.0028 | |
| SRP219564 | ZDHHC4 | 55146 | RNAseq | 0.4328 | 0.3414 | |
| TCGA | ZDHHC4 | 55146 | RNAseq | -0.0024 | 0.9711 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZDHHC4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC4 | 55146 | 14 | 1 | 15 | |
| GSE20123 | ZDHHC4 | 55146 | 14 | 1 | 15 | |
| GSE43470 | ZDHHC4 | 55146 | 7 | 1 | 35 | |
| GSE46452 | ZDHHC4 | 55146 | 13 | 1 | 45 | |
| GSE47630 | ZDHHC4 | 55146 | 9 | 1 | 30 | |
| GSE54993 | ZDHHC4 | 55146 | 0 | 6 | 64 | |
| GSE54994 | ZDHHC4 | 55146 | 20 | 1 | 32 | |
| GSE60625 | ZDHHC4 | 55146 | 0 | 0 | 11 | |
| GSE74703 | ZDHHC4 | 55146 | 7 | 0 | 29 | |
| GSE74704 | ZDHHC4 | 55146 | 9 | 0 | 11 | |
| TCGA | ZDHHC4 | 55146 | 56 | 4 | 36 |
Total number of gains: 149; Total number of losses: 16; Total Number of normals: 323.
Somatic mutations of ZDHHC4:
Generating mutation plots.
Highly correlated genes for ZDHHC4:
Showing top 20/1161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC4 | MRPL10 | 0.778715 | 3 | 0 | 3 |
| ZDHHC4 | TMTC1 | 0.76645 | 4 | 0 | 4 |
| ZDHHC4 | C1orf131 | 0.760737 | 3 | 0 | 3 |
| ZDHHC4 | NOLC1 | 0.755356 | 3 | 0 | 3 |
| ZDHHC4 | C12orf57 | 0.750587 | 4 | 0 | 4 |
| ZDHHC4 | TMEM98 | 0.74783 | 3 | 0 | 3 |
| ZDHHC4 | ARL6IP6 | 0.742005 | 3 | 0 | 3 |
| ZDHHC4 | TGFBR2 | 0.733248 | 3 | 0 | 3 |
| ZDHHC4 | UNC119 | 0.732027 | 3 | 0 | 3 |
| ZDHHC4 | TNRC6B | 0.7303 | 3 | 0 | 3 |
| ZDHHC4 | FAM98B | 0.728713 | 4 | 0 | 3 |
| ZDHHC4 | ZNF260 | 0.727203 | 3 | 0 | 3 |
| ZDHHC4 | UBR1 | 0.721801 | 4 | 0 | 4 |
| ZDHHC4 | VKORC1 | 0.718032 | 7 | 0 | 6 |
| ZDHHC4 | RPS27L | 0.717776 | 3 | 0 | 3 |
| ZDHHC4 | DHX33 | 0.717452 | 3 | 0 | 3 |
| ZDHHC4 | EID1 | 0.71202 | 6 | 0 | 5 |
| ZDHHC4 | KLHL13 | 0.710024 | 4 | 0 | 3 |
| ZDHHC4 | NIF3L1 | 0.709992 | 5 | 0 | 4 |
| ZDHHC4 | RNF166 | 0.708458 | 3 | 0 | 3 |
For details and further investigation, click here
