CETP

 

Full name: cholesteryl ester transfer protein Alias Symbol: BPIFF
Type: protein-coding gene Cytoband: 16q13
Entrez ID: 1071 HGNC ID: HGNC:1869 Ensembl Gene: ENSG00000087237 OMIM ID: 118470
Drug and gene relationship at DGIdb

 

Expression of CETP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CETP 1071 206210_s_at 0.1779 0.7168
GSE20347 CETP 1071 206210_s_at 0.0499 0.5575
GSE23400 CETP 1071 206210_s_at -0.1678 0.0006
GSE26886 CETP 1071 206210_s_at 0.0433 0.8153
GSE29001 CETP 1071 206210_s_at -0.2198 0.0746
GSE38129 CETP 1071 206210_s_at -0.1090 0.2320
GSE45670 CETP 1071 206210_s_at 0.1617 0.1834
GSE53622 CETP 1071 88940 0.6529 0.0045
GSE53624 CETP 1071 88940 0.5645 0.0101
GSE63941 CETP 1071 206210_s_at 0.2423 0.1354
GSE77861 CETP 1071 206210_s_at -0.0040 0.9740
GSE97050 CETP 1071 A_23_P49376 0.1177 0.5725
SRP064894 CETP 1071 RNAseq 2.1721 0.0000
SRP133303 CETP 1071 RNAseq 0.3725 0.2743
SRP159526 CETP 1071 RNAseq -0.3777 0.4802
SRP219564 CETP 1071 RNAseq 1.4535 0.0331
TCGA CETP 1071 RNAseq 1.0518 0.0218

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by CETP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CETP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CETP 1071 6 0 24
GSE20123 CETP 1071 6 1 23
GSE43470 CETP 1071 3 6 34
GSE46452 CETP 1071 38 1 20
GSE47630 CETP 1071 10 8 22
GSE54993 CETP 1071 2 4 64
GSE54994 CETP 1071 7 10 36
GSE60625 CETP 1071 4 0 7
GSE74703 CETP 1071 3 3 30
GSE74704 CETP 1071 5 0 15
TCGA CETP 1071 25 13 58

Total number of gains: 109; Total number of losses: 46; Total Number of normals: 333.  


 

Somatic mutations of CETP:

 

Generating mutation plots.

 

Highly correlated genes for CETP:

 

Showing top 20/362 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CETPCXCR60.690889505
CETPDTX10.690569303
CETPABCA40.670248404
CETPASIC20.669088303
CETPOR2J30.668053303
CETPCER10.664786303
CETPSULT2A10.659795303
CETPKIR2DL30.65825303
CETPC5AR10.646531404
CETPACVR2B-AS10.643471404
CETPSH2B30.643241505
CETPTNMD0.641077303
CETPTNFAIP8L20.640471404
CETPKRTAP1-10.636171505
CETPCD1B0.635653503
CETPGAD20.635643404
CETPCHRM50.635461504
CETPCKM0.634016404
CETPRRH0.630403303
CETPUCP10.626578504

For details and further investigation, click here