| Full name: coiled-coil domain containing 40 | Alias Symbol: FLJ20753|KIAA1640|FLJ32021|CILD15|FAP172 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 55036 | HGNC ID: HGNC:26090 | Ensembl Gene: ENSG00000141519 | OMIM ID: 613799 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC40 | 55036 | 229918_at | -0.0245 | 0.9162 | |
| GSE20347 | CCDC40 | 55036 | 220593_s_at | 0.0907 | 0.2654 | |
| GSE23400 | CCDC40 | 55036 | 220592_at | -0.0467 | 0.2242 | |
| GSE26886 | CCDC40 | 55036 | 229918_at | 0.2671 | 0.0205 | |
| GSE29001 | CCDC40 | 55036 | 220592_at | 0.1569 | 0.3290 | |
| GSE38129 | CCDC40 | 55036 | 220593_s_at | 0.0620 | 0.6058 | |
| GSE45670 | CCDC40 | 55036 | 229918_at | -0.1096 | 0.2327 | |
| GSE53622 | CCDC40 | 55036 | 36678 | -0.1435 | 0.2081 | |
| GSE53624 | CCDC40 | 55036 | 36678 | 0.2650 | 0.0097 | |
| GSE63941 | CCDC40 | 55036 | 220593_s_at | -0.1825 | 0.2410 | |
| GSE77861 | CCDC40 | 55036 | 229918_at | -0.0876 | 0.5426 | |
| GSE97050 | CCDC40 | 55036 | A_24_P160680 | -0.7657 | 0.2041 | |
| SRP064894 | CCDC40 | 55036 | RNAseq | 0.5168 | 0.0246 | |
| SRP133303 | CCDC40 | 55036 | RNAseq | 0.0324 | 0.8750 | |
| SRP159526 | CCDC40 | 55036 | RNAseq | 0.6062 | 0.0709 | |
| SRP193095 | CCDC40 | 55036 | RNAseq | 0.6607 | 0.0002 | |
| SRP219564 | CCDC40 | 55036 | RNAseq | 0.2367 | 0.6563 | |
| TCGA | CCDC40 | 55036 | RNAseq | -0.4236 | 0.0277 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC40 | 55036 | 4 | 3 | 23 | |
| GSE20123 | CCDC40 | 55036 | 4 | 3 | 23 | |
| GSE43470 | CCDC40 | 55036 | 2 | 6 | 35 | |
| GSE46452 | CCDC40 | 55036 | 34 | 0 | 25 | |
| GSE47630 | CCDC40 | 55036 | 9 | 1 | 30 | |
| GSE54993 | CCDC40 | 55036 | 2 | 5 | 63 | |
| GSE54994 | CCDC40 | 55036 | 10 | 6 | 37 | |
| GSE60625 | CCDC40 | 55036 | 6 | 0 | 5 | |
| GSE74703 | CCDC40 | 55036 | 2 | 4 | 30 | |
| GSE74704 | CCDC40 | 55036 | 4 | 3 | 13 | |
| TCGA | CCDC40 | 55036 | 29 | 9 | 58 |
Total number of gains: 106; Total number of losses: 40; Total Number of normals: 342.
Somatic mutations of CCDC40:
Generating mutation plots.
Highly correlated genes for CCDC40:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC40 | GBA2 | 0.764927 | 3 | 0 | 3 |
| CCDC40 | GRIN3B | 0.715265 | 3 | 0 | 3 |
| CCDC40 | NEK1 | 0.70967 | 3 | 0 | 3 |
| CCDC40 | PHRF1 | 0.702618 | 3 | 0 | 3 |
| CCDC40 | UBQLN4 | 0.698671 | 4 | 0 | 3 |
| CCDC40 | VAMP2 | 0.696973 | 5 | 0 | 4 |
| CCDC40 | CCDC154 | 0.694264 | 4 | 0 | 4 |
| CCDC40 | KLHL23 | 0.691733 | 3 | 0 | 3 |
| CCDC40 | TP53I11 | 0.689558 | 3 | 0 | 3 |
| CCDC40 | BCAN | 0.688819 | 4 | 0 | 4 |
| CCDC40 | SOX10 | 0.687666 | 4 | 0 | 4 |
| CCDC40 | MYEF2 | 0.685062 | 4 | 0 | 3 |
| CCDC40 | SEMA6A | 0.683733 | 3 | 0 | 3 |
| CCDC40 | C16orf86 | 0.681063 | 4 | 0 | 3 |
| CCDC40 | MRPL52 | 0.676094 | 3 | 0 | 3 |
| CCDC40 | ZNF362 | 0.673358 | 4 | 0 | 3 |
| CCDC40 | ATXN2L | 0.670824 | 4 | 0 | 4 |
| CCDC40 | PDLIM7 | 0.668442 | 4 | 0 | 3 |
| CCDC40 | GRASP | 0.665887 | 5 | 0 | 5 |
| CCDC40 | TCF15 | 0.664815 | 4 | 0 | 4 |
For details and further investigation, click here
