KTN1

 

Full name: kinectin 1 Alias Symbol: KIAA0004|CG1|KNT
Type: protein-coding gene Cytoband: 14q22.1
Entrez ID: 3895 HGNC ID: HGNC:6467 Ensembl Gene: ENSG00000126777 OMIM ID: 600381
Drug and gene relationship at DGIdb

 

Expression of KTN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KTN1 3895 200915_x_at 0.2149 0.6192
GSE20347 KTN1 3895 200915_x_at 0.1749 0.2897
GSE23400 KTN1 3895 200915_x_at 0.6223 0.0000
GSE26886 KTN1 3895 200915_x_at 1.2022 0.0000
GSE29001 KTN1 3895 200915_x_at 0.2731 0.3733
GSE38129 KTN1 3895 200915_x_at 0.1646 0.1387
GSE45670 KTN1 3895 200915_x_at 0.2094 0.2074
GSE53622 KTN1 3895 43286 0.5296 0.0000
GSE53624 KTN1 3895 43286 0.4882 0.0000
GSE63941 KTN1 3895 200915_x_at -0.1288 0.8216
GSE77861 KTN1 3895 200915_x_at 0.5648 0.1869
GSE97050 KTN1 3895 A_33_P3348639 0.2811 0.3379
SRP007169 KTN1 3895 RNAseq 1.2724 0.0114
SRP008496 KTN1 3895 RNAseq 1.4363 0.0000
SRP064894 KTN1 3895 RNAseq 0.2843 0.1015
SRP133303 KTN1 3895 RNAseq 0.4881 0.0013
SRP159526 KTN1 3895 RNAseq 0.3505 0.3127
SRP193095 KTN1 3895 RNAseq 0.4022 0.0305
SRP219564 KTN1 3895 RNAseq 0.1431 0.7223
TCGA KTN1 3895 RNAseq 0.0846 0.0887

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by KTN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KTN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KTN1 3895 8 3 19
GSE20123 KTN1 3895 8 3 19
GSE43470 KTN1 3895 8 1 34
GSE46452 KTN1 3895 16 3 40
GSE47630 KTN1 3895 11 10 19
GSE54993 KTN1 3895 3 8 59
GSE54994 KTN1 3895 19 4 30
GSE60625 KTN1 3895 0 2 9
GSE74703 KTN1 3895 7 1 28
GSE74704 KTN1 3895 3 2 15
TCGA KTN1 3895 32 14 50

Total number of gains: 115; Total number of losses: 51; Total Number of normals: 322.  


 

Somatic mutations of KTN1:

 

Generating mutation plots.

 

Highly correlated genes for KTN1:

 

Showing top 20/1323 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KTN1THEM40.862698303
KTN1PET1170.853912303
KTN1TIMM90.76225312012
KTN1MNAT10.75541112012
KTN1FERMT20.751079303
KTN1SNW10.74718210010
KTN1FARS20.745408303
KTN1MRPS50.739918303
KTN1COCH0.731243505
KTN1WDR540.726595606
KTN1SCAMP10.725764303
KTN1SOCS40.718132909
KTN1UBTD20.709967707
KTN1CEP630.709896404
KTN1RNMT0.703577404
KTN1SMARCAL10.702023303
KTN1UAP10.701495303
KTN1NPHP30.693605403
KTN1IFT430.691171606
KTN1CENPU0.687365303

For details and further investigation, click here