| Full name: centromere protein U | Alias Symbol: CENP-U|KLIP1|CENP-50|PBIP1 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 79682 | HGNC ID: HGNC:21348 | Ensembl Gene: ENSG00000151725 | OMIM ID: 611511 |
Screen Evidence:
| |||
Expression of CENPU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPU | 79682 | 218883_s_at | 0.3423 | 0.6019 | |
| GSE20347 | CENPU | 79682 | 218883_s_at | 0.3585 | 0.1520 | |
| GSE23400 | CENPU | 79682 | 218883_s_at | 0.3672 | 0.0099 | |
| GSE26886 | CENPU | 79682 | 218883_s_at | 0.6868 | 0.0076 | |
| GSE29001 | CENPU | 79682 | 218883_s_at | 0.4334 | 0.4924 | |
| GSE38129 | CENPU | 79682 | 218883_s_at | 1.0657 | 0.0015 | |
| GSE45670 | CENPU | 79682 | 218883_s_at | 0.3355 | 0.1570 | |
| GSE53622 | CENPU | 79682 | 16616 | 0.5640 | 0.0021 | |
| GSE53624 | CENPU | 79682 | 16616 | 0.3983 | 0.0000 | |
| GSE63941 | CENPU | 79682 | 218883_s_at | 3.1016 | 0.0001 | |
| GSE77861 | CENPU | 79682 | 218883_s_at | 0.5870 | 0.1818 | |
| SRP007169 | CENPU | 79682 | RNAseq | -0.0131 | 0.9795 | |
| SRP008496 | CENPU | 79682 | RNAseq | -0.0146 | 0.9640 | |
| SRP064894 | CENPU | 79682 | RNAseq | 0.0735 | 0.7982 | |
| SRP133303 | CENPU | 79682 | RNAseq | 0.7206 | 0.0134 | |
| SRP159526 | CENPU | 79682 | RNAseq | 0.6184 | 0.2658 | |
| SRP193095 | CENPU | 79682 | RNAseq | -0.0961 | 0.6232 | |
| SRP219564 | CENPU | 79682 | RNAseq | 0.1506 | 0.7752 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CENPU expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CENPU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPU | 79682 | 3 | 13 | 14 | |
| GSE20123 | CENPU | 79682 | 3 | 13 | 14 | |
| GSE43470 | CENPU | 79682 | 1 | 12 | 30 | |
| GSE46452 | CENPU | 79682 | 1 | 36 | 22 | |
| GSE47630 | CENPU | 79682 | 0 | 22 | 18 | |
| GSE54993 | CENPU | 79682 | 10 | 0 | 60 | |
| GSE54994 | CENPU | 79682 | 2 | 12 | 39 | |
| GSE60625 | CENPU | 79682 | 0 | 0 | 11 | |
| GSE74703 | CENPU | 79682 | 1 | 9 | 26 | |
| GSE74704 | CENPU | 79682 | 1 | 6 | 13 |
Total number of gains: 22; Total number of losses: 123; Total Number of normals: 247.
Somatic mutations of CENPU:
Generating mutation plots.
Highly correlated genes for CENPU:
Showing top 20/278 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPU | KTN1 | 0.687365 | 3 | 0 | 3 |
| CENPU | SQLE | 0.655167 | 3 | 0 | 3 |
| CENPU | HAUS6 | 0.647831 | 4 | 0 | 3 |
| CENPU | RACGAP1 | 0.642356 | 8 | 0 | 6 |
| CENPU | ADSL | 0.641918 | 3 | 0 | 3 |
| CENPU | ATP11C | 0.634426 | 3 | 0 | 3 |
| CENPU | MNAT1 | 0.632279 | 4 | 0 | 3 |
| CENPU | SFR1 | 0.625474 | 4 | 0 | 4 |
| CENPU | HMGB2 | 0.616585 | 9 | 0 | 8 |
| CENPU | METTL5 | 0.615976 | 4 | 0 | 4 |
| CENPU | CENPK | 0.615575 | 5 | 0 | 3 |
| CENPU | ADAM10 | 0.612075 | 6 | 0 | 5 |
| CENPU | NCAPG | 0.611398 | 9 | 0 | 6 |
| CENPU | RUVBL2 | 0.608415 | 7 | 0 | 6 |
| CENPU | SMC4 | 0.607116 | 7 | 0 | 5 |
| CENPU | COCH | 0.604644 | 4 | 0 | 3 |
| CENPU | PRPS2 | 0.602748 | 3 | 0 | 3 |
| CENPU | PLK4 | 0.602126 | 9 | 0 | 6 |
| CENPU | NEIL3 | 0.600543 | 5 | 0 | 3 |
| CENPU | TMEM68 | 0.597447 | 4 | 0 | 3 |
For details and further investigation, click here
