| Full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 | Alias Symbol: HHARP|HARP | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 50485 | HGNC ID: HGNC:11102 | Ensembl Gene: ENSG00000138375 | OMIM ID: 606622 |
| Drug and gene relationship at DGIdb | |||
Expression of SMARCAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMARCAL1 | 50485 | 218452_at | -0.0183 | 0.9676 | |
| GSE20347 | SMARCAL1 | 50485 | 218452_at | -0.3797 | 0.0006 | |
| GSE23400 | SMARCAL1 | 50485 | 218452_at | 0.0647 | 0.0700 | |
| GSE26886 | SMARCAL1 | 50485 | 218452_at | 0.3846 | 0.0094 | |
| GSE29001 | SMARCAL1 | 50485 | 218452_at | -0.0429 | 0.8276 | |
| GSE38129 | SMARCAL1 | 50485 | 218452_at | -0.1788 | 0.0721 | |
| GSE45670 | SMARCAL1 | 50485 | 218452_at | 0.0885 | 0.5896 | |
| GSE53622 | SMARCAL1 | 50485 | 156341 | 0.0080 | 0.9352 | |
| GSE53624 | SMARCAL1 | 50485 | 156341 | 0.1742 | 0.0004 | |
| GSE63941 | SMARCAL1 | 50485 | 218452_at | -0.3691 | 0.2573 | |
| GSE77861 | SMARCAL1 | 50485 | 218452_at | -0.0308 | 0.9031 | |
| GSE97050 | SMARCAL1 | 50485 | A_33_P3217834 | 0.2245 | 0.3709 | |
| SRP007169 | SMARCAL1 | 50485 | RNAseq | -0.3426 | 0.3680 | |
| SRP008496 | SMARCAL1 | 50485 | RNAseq | -0.1669 | 0.4501 | |
| SRP064894 | SMARCAL1 | 50485 | RNAseq | 0.4499 | 0.0118 | |
| SRP133303 | SMARCAL1 | 50485 | RNAseq | 0.0565 | 0.7455 | |
| SRP159526 | SMARCAL1 | 50485 | RNAseq | -0.0114 | 0.9609 | |
| SRP193095 | SMARCAL1 | 50485 | RNAseq | -0.1404 | 0.1649 | |
| SRP219564 | SMARCAL1 | 50485 | RNAseq | 0.2039 | 0.4909 | |
| TCGA | SMARCAL1 | 50485 | RNAseq | 0.0452 | 0.4139 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMARCAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMARCAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMARCAL1 | 50485 | 1 | 13 | 16 | |
| GSE20123 | SMARCAL1 | 50485 | 1 | 13 | 16 | |
| GSE43470 | SMARCAL1 | 50485 | 0 | 7 | 36 | |
| GSE46452 | SMARCAL1 | 50485 | 0 | 5 | 54 | |
| GSE47630 | SMARCAL1 | 50485 | 4 | 5 | 31 | |
| GSE54993 | SMARCAL1 | 50485 | 0 | 3 | 67 | |
| GSE54994 | SMARCAL1 | 50485 | 8 | 9 | 36 | |
| GSE60625 | SMARCAL1 | 50485 | 0 | 3 | 8 | |
| GSE74703 | SMARCAL1 | 50485 | 0 | 6 | 30 | |
| GSE74704 | SMARCAL1 | 50485 | 1 | 7 | 12 | |
| TCGA | SMARCAL1 | 50485 | 11 | 28 | 57 |
Total number of gains: 26; Total number of losses: 99; Total Number of normals: 363.
Somatic mutations of SMARCAL1:
Generating mutation plots.
Highly correlated genes for SMARCAL1:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMARCAL1 | DYNC2H1 | 0.802392 | 3 | 0 | 3 |
| SMARCAL1 | SLC37A3 | 0.776513 | 3 | 0 | 3 |
| SMARCAL1 | CEP63 | 0.776302 | 3 | 0 | 3 |
| SMARCAL1 | ORC5 | 0.735084 | 3 | 0 | 3 |
| SMARCAL1 | RNF187 | 0.726177 | 3 | 0 | 3 |
| SMARCAL1 | HERPUD2 | 0.724787 | 3 | 0 | 3 |
| SMARCAL1 | TRAF7 | 0.724023 | 3 | 0 | 3 |
| SMARCAL1 | KIAA0895 | 0.72005 | 3 | 0 | 3 |
| SMARCAL1 | OTUD7B | 0.715495 | 3 | 0 | 3 |
| SMARCAL1 | BMP2 | 0.713813 | 3 | 0 | 3 |
| SMARCAL1 | ZNF830 | 0.707921 | 3 | 0 | 3 |
| SMARCAL1 | THEM4 | 0.703955 | 3 | 0 | 3 |
| SMARCAL1 | PTPN1 | 0.703741 | 3 | 0 | 3 |
| SMARCAL1 | ABCB10 | 0.703295 | 3 | 0 | 3 |
| SMARCAL1 | ASB7 | 0.703094 | 3 | 0 | 3 |
| SMARCAL1 | KTN1 | 0.702023 | 3 | 0 | 3 |
| SMARCAL1 | TRUB1 | 0.700479 | 3 | 0 | 3 |
| SMARCAL1 | SPIRE1 | 0.697088 | 3 | 0 | 3 |
| SMARCAL1 | LAMTOR3 | 0.695864 | 4 | 0 | 3 |
| SMARCAL1 | KIF3A | 0.695731 | 3 | 0 | 3 |
For details and further investigation, click here
