| Full name: protein phosphatase 1 regulatory subunit 9B | Alias Symbol: Spn|SPINO | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 84687 | HGNC ID: HGNC:9298 | Ensembl Gene: ENSG00000108819 | OMIM ID: 603325 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R9B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R9B | 84687 | 225124_at | 0.7652 | 0.0610 | |
| GSE26886 | PPP1R9B | 84687 | 225124_at | 0.1508 | 0.3344 | |
| GSE45670 | PPP1R9B | 84687 | 225124_at | 0.3592 | 0.0011 | |
| GSE53622 | PPP1R9B | 84687 | 123969 | 0.1580 | 0.0013 | |
| GSE53624 | PPP1R9B | 84687 | 123969 | 0.0758 | 0.2581 | |
| GSE63941 | PPP1R9B | 84687 | 225124_at | 1.1318 | 0.0138 | |
| GSE77861 | PPP1R9B | 84687 | 225124_at | 0.3426 | 0.3323 | |
| GSE97050 | PPP1R9B | 84687 | A_24_P376309 | 0.7625 | 0.1186 | |
| SRP007169 | PPP1R9B | 84687 | RNAseq | 1.2899 | 0.0182 | |
| SRP008496 | PPP1R9B | 84687 | RNAseq | 1.1132 | 0.0037 | |
| SRP064894 | PPP1R9B | 84687 | RNAseq | 0.3147 | 0.0822 | |
| SRP133303 | PPP1R9B | 84687 | RNAseq | 0.2636 | 0.1442 | |
| SRP159526 | PPP1R9B | 84687 | RNAseq | 0.1190 | 0.6167 | |
| SRP193095 | PPP1R9B | 84687 | RNAseq | 0.3493 | 0.0283 | |
| SRP219564 | PPP1R9B | 84687 | RNAseq | 0.3175 | 0.3801 | |
| TCGA | PPP1R9B | 84687 | RNAseq | 0.1730 | 0.0003 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PPP1R9B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R9B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R9B | 84687 | 5 | 2 | 23 | |
| GSE20123 | PPP1R9B | 84687 | 5 | 2 | 23 | |
| GSE43470 | PPP1R9B | 84687 | 3 | 2 | 38 | |
| GSE46452 | PPP1R9B | 84687 | 32 | 0 | 27 | |
| GSE47630 | PPP1R9B | 84687 | 9 | 0 | 31 | |
| GSE54993 | PPP1R9B | 84687 | 2 | 4 | 64 | |
| GSE54994 | PPP1R9B | 84687 | 9 | 6 | 38 | |
| GSE60625 | PPP1R9B | 84687 | 4 | 0 | 7 | |
| GSE74703 | PPP1R9B | 84687 | 3 | 2 | 31 | |
| GSE74704 | PPP1R9B | 84687 | 4 | 1 | 15 | |
| TCGA | PPP1R9B | 84687 | 27 | 7 | 62 |
Total number of gains: 103; Total number of losses: 26; Total Number of normals: 359.
Somatic mutations of PPP1R9B:
Generating mutation plots.
Highly correlated genes for PPP1R9B:
Showing top 20/638 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R9B | GART | 0.828145 | 3 | 0 | 3 |
| PPP1R9B | DOLK | 0.79043 | 3 | 0 | 3 |
| PPP1R9B | IFRD2 | 0.789777 | 3 | 0 | 3 |
| PPP1R9B | RPN1 | 0.788374 | 3 | 0 | 3 |
| PPP1R9B | CHD3 | 0.783659 | 3 | 0 | 3 |
| PPP1R9B | KIF23 | 0.781577 | 3 | 0 | 3 |
| PPP1R9B | PRKDC | 0.774238 | 3 | 0 | 3 |
| PPP1R9B | PLXNA1 | 0.773094 | 3 | 0 | 3 |
| PPP1R9B | NCBP1 | 0.772423 | 3 | 0 | 3 |
| PPP1R9B | INTS1 | 0.765264 | 4 | 0 | 4 |
| PPP1R9B | DSCC1 | 0.764519 | 3 | 0 | 3 |
| PPP1R9B | TGFB1 | 0.763613 | 3 | 0 | 3 |
| PPP1R9B | YARS2 | 0.763332 | 3 | 0 | 3 |
| PPP1R9B | SEC61A1 | 0.762182 | 3 | 0 | 3 |
| PPP1R9B | ACTL6A | 0.761874 | 3 | 0 | 3 |
| PPP1R9B | MRPL47 | 0.761224 | 3 | 0 | 3 |
| PPP1R9B | NCAPG | 0.760731 | 3 | 0 | 3 |
| PPP1R9B | FAM89B | 0.760323 | 3 | 0 | 3 |
| PPP1R9B | GRWD1 | 0.755721 | 3 | 0 | 3 |
| PPP1R9B | WDR4 | 0.754213 | 4 | 0 | 4 |
For details and further investigation, click here
