VCAN

 

Full name: versican Alias Symbol: PG-M
Type: protein-coding gene Cytoband: 5q14.2-q14.3
Entrez ID: 1462 HGNC ID: HGNC:2464 Ensembl Gene: ENSG00000038427 OMIM ID: 118661
Drug and gene relationship at DGIdb

 

Expression of VCAN:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VCAN 1462 221731_x_at 1.1594 0.2751
GSE20347 VCAN 1462 221731_x_at 3.2889 0.0000
GSE23400 VCAN 1462 204620_s_at 2.3114 0.0000
GSE26886 VCAN 1462 221731_x_at 4.8339 0.0000
GSE29001 VCAN 1462 221731_x_at 2.6046 0.0000
GSE38129 VCAN 1462 221731_x_at 2.8484 0.0000
GSE45670 VCAN 1462 221731_x_at -0.0373 0.9696
GSE53622 VCAN 1462 149237 2.4880 0.0000
GSE53624 VCAN 1462 149237 2.9818 0.0000
GSE63941 VCAN 1462 204620_s_at -7.1367 0.0000
GSE77861 VCAN 1462 204620_s_at 2.0880 0.0060
GSE97050 VCAN 1462 A_23_P144959 2.2240 0.0502
SRP007169 VCAN 1462 RNAseq 6.2129 0.0000
SRP008496 VCAN 1462 RNAseq 6.3952 0.0000
SRP064894 VCAN 1462 RNAseq 2.7293 0.0000
SRP133303 VCAN 1462 RNAseq 3.1650 0.0000
SRP159526 VCAN 1462 RNAseq 3.3731 0.0000
SRP193095 VCAN 1462 RNAseq 2.7256 0.0000
SRP219564 VCAN 1462 RNAseq 2.9262 0.0002
TCGA VCAN 1462 RNAseq 0.2652 0.0488

Upregulated datasets: 15; Downregulated datasets: 1.  

 

Survival by VCAN expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of VCAN:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VCAN 1462 1 14 15
GSE20123 VCAN 1462 1 14 15
GSE43470 VCAN 1462 2 10 31
GSE46452 VCAN 1462 0 28 31
GSE47630 VCAN 1462 1 19 20
GSE54993 VCAN 1462 8 1 61
GSE54994 VCAN 1462 1 18 34
GSE60625 VCAN 1462 0 0 11
GSE74703 VCAN 1462 1 7 28
GSE74704 VCAN 1462 1 7 12
TCGA VCAN 1462 4 47 45

Total number of gains: 20; Total number of losses: 165; Total Number of normals: 303.  

 

Somatic mutations of VCAN:

 

Generating mutation plots.

 

Highly correlated genes for VCAN:

 

Showing top 20/1314 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VCANCOL6A30.91933513013
VCANSPARC0.89308413013
VCANPOSTN0.88869713013
VCANCOL3A10.88607913013
VCANCDH110.88201513013
VCANCOL1A20.87586813012
VCANCOL5A20.87424713013
VCANSULF10.87332113013
VCANCTSK0.8627813013
VCANCOL1A10.85344912012
VCANCOL5A10.84918113013
VCANTHY10.843213013
VCANFN10.8366112012
VCANFAP0.83349911011
VCANPCOLCE0.83293413013
VCANLUM0.82897913013
VCANCALU0.81852612012
VCANCOL12A10.817562909
VCANPXDN0.8120413013
VCANMMD0.81182313013

For details and further investigation, click here