LGALS1

 

Full name: galectin 1 Alias Symbol: GBP
Type: protein-coding gene Cytoband: 22q13.1
Entrez ID: 3956 HGNC ID: HGNC:6561 Ensembl Gene: ENSG00000100097 OMIM ID: 150570
Drug and gene relationship at DGIdb

 

Expression of LGALS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LGALS1 3956 201105_at 0.7507 0.4399
GSE20347 LGALS1 3956 201105_at 1.9039 0.0000
GSE23400 LGALS1 3956 201105_at 1.0047 0.0000
GSE26886 LGALS1 3956 201105_at 3.6978 0.0000
GSE29001 LGALS1 3956 201105_at 1.6359 0.0096
GSE38129 LGALS1 3956 201105_at 1.2594 0.0096
GSE45670 LGALS1 3956 201105_at -0.0758 0.9293
GSE53622 LGALS1 3956 97973 1.6504 0.0000
GSE53624 LGALS1 3956 97973 2.2807 0.0000
GSE63941 LGALS1 3956 201105_at -1.6577 0.2865
GSE77861 LGALS1 3956 201105_at 2.4664 0.0105
GSE97050 LGALS1 3956 A_23_P166459 0.8627 0.1782
SRP007169 LGALS1 3956 RNAseq 3.8142 0.0000
SRP008496 LGALS1 3956 RNAseq 3.5702 0.0000
SRP064894 LGALS1 3956 RNAseq 2.0352 0.0000
SRP133303 LGALS1 3956 RNAseq 1.8980 0.0000
SRP159526 LGALS1 3956 RNAseq 1.1990 0.0068
SRP193095 LGALS1 3956 RNAseq 2.9182 0.0000
SRP219564 LGALS1 3956 RNAseq 0.8831 0.3159
TCGA LGALS1 3956 RNAseq 0.3894 0.0002

Upregulated datasets: 14; Downregulated datasets: 0.  

 

Survival by LGALS1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LGALS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LGALS1 3956 6 5 19
GSE20123 LGALS1 3956 6 4 20
GSE43470 LGALS1 3956 4 6 33
GSE46452 LGALS1 3956 32 2 25
GSE47630 LGALS1 3956 9 4 27
GSE54993 LGALS1 3956 3 6 61
GSE54994 LGALS1 3956 9 8 36
GSE60625 LGALS1 3956 5 0 6
GSE74703 LGALS1 3956 4 4 28
GSE74704 LGALS1 3956 3 2 15
TCGA LGALS1 3956 27 15 54

Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.  

 

Somatic mutations of LGALS1:

 

Generating mutation plots.

 

Highly correlated genes for LGALS1:

 

Showing top 20/1504 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LGALS1HTRA10.81926912012
LGALS1COL4A20.81016712011
LGALS1INHBA0.79937412011
LGALS1COL12A10.795251908
LGALS1COL5A20.78967612012
LGALS1FN10.78551912012
LGALS1ENAH0.78461911011
LGALS1COL5A10.78150313012
LGALS1FSTL10.78074612012
LGALS1LOXL20.7786412012
LGALS1SPARC0.77835513011
LGALS1AEBP10.77581512012
LGALS1COL4A10.77024412011
LGALS1FADS10.768255303
LGALS1COL6A10.76672213012
LGALS1MMD0.76611313013
LGALS1IGFBP70.7641312011
LGALS1COL6A30.76268813012
LGALS1EMP30.75949413013
LGALS1TGFBI0.75892613013

For details and further investigation, click here