| Full name: SET domain containing 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.12 | ||
| Entrez ID: 54093 | HGNC ID: HGNC:1258 | Ensembl Gene: ENSG00000185917 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SETD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SETD4 | 54093 | 219482_at | -0.0388 | 0.9510 | |
| GSE20347 | SETD4 | 54093 | 213989_x_at | -0.2038 | 0.1154 | |
| GSE23400 | SETD4 | 54093 | 213989_x_at | -0.1291 | 0.0200 | |
| GSE26886 | SETD4 | 54093 | 213989_x_at | 0.0282 | 0.9319 | |
| GSE29001 | SETD4 | 54093 | 213989_x_at | -0.2325 | 0.2219 | |
| GSE38129 | SETD4 | 54093 | 213989_x_at | -0.0141 | 0.9354 | |
| GSE45670 | SETD4 | 54093 | 219482_at | -0.1401 | 0.2690 | |
| GSE53622 | SETD4 | 54093 | 18616 | -0.1659 | 0.0505 | |
| GSE53624 | SETD4 | 54093 | 18616 | -0.0991 | 0.3017 | |
| GSE63941 | SETD4 | 54093 | 213989_x_at | 0.4669 | 0.3501 | |
| GSE77861 | SETD4 | 54093 | 213989_x_at | -0.4692 | 0.0635 | |
| GSE97050 | SETD4 | 54093 | A_24_P228637 | -0.1333 | 0.6547 | |
| SRP007169 | SETD4 | 54093 | RNAseq | -0.1008 | 0.8660 | |
| SRP064894 | SETD4 | 54093 | RNAseq | 0.0952 | 0.5244 | |
| SRP133303 | SETD4 | 54093 | RNAseq | -0.3567 | 0.0109 | |
| SRP159526 | SETD4 | 54093 | RNAseq | 0.1820 | 0.5347 | |
| SRP193095 | SETD4 | 54093 | RNAseq | -0.2287 | 0.0239 | |
| SRP219564 | SETD4 | 54093 | RNAseq | -0.1288 | 0.7620 | |
| TCGA | SETD4 | 54093 | RNAseq | -0.0079 | 0.9094 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SETD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SETD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SETD4 | 54093 | 2 | 8 | 20 | |
| GSE20123 | SETD4 | 54093 | 2 | 9 | 19 | |
| GSE43470 | SETD4 | 54093 | 1 | 11 | 31 | |
| GSE46452 | SETD4 | 54093 | 1 | 21 | 37 | |
| GSE47630 | SETD4 | 54093 | 6 | 17 | 17 | |
| GSE54993 | SETD4 | 54093 | 8 | 1 | 61 | |
| GSE54994 | SETD4 | 54093 | 2 | 9 | 42 | |
| GSE60625 | SETD4 | 54093 | 0 | 0 | 11 | |
| GSE74703 | SETD4 | 54093 | 1 | 8 | 27 | |
| GSE74704 | SETD4 | 54093 | 1 | 5 | 14 | |
| TCGA | SETD4 | 54093 | 9 | 39 | 48 |
Total number of gains: 33; Total number of losses: 128; Total Number of normals: 327.
Somatic mutations of SETD4:
Generating mutation plots.
Highly correlated genes for SETD4:
Showing top 20/162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SETD4 | GGA3 | 0.770056 | 3 | 0 | 3 |
| SETD4 | PRDM4 | 0.748195 | 3 | 0 | 3 |
| SETD4 | ZNF202 | 0.744688 | 3 | 0 | 3 |
| SETD4 | MTRF1 | 0.743816 | 3 | 0 | 3 |
| SETD4 | LCOR | 0.742768 | 3 | 0 | 3 |
| SETD4 | WBP2 | 0.741337 | 3 | 0 | 3 |
| SETD4 | XPC | 0.741038 | 3 | 0 | 3 |
| SETD4 | TMEM120A | 0.737991 | 3 | 0 | 3 |
| SETD4 | ZFYVE27 | 0.737669 | 3 | 0 | 3 |
| SETD4 | ADCK1 | 0.723265 | 3 | 0 | 3 |
| SETD4 | DLL1 | 0.721443 | 3 | 0 | 3 |
| SETD4 | TBRG1 | 0.71203 | 3 | 0 | 3 |
| SETD4 | OXNAD1 | 0.710851 | 3 | 0 | 3 |
| SETD4 | RAP1GDS1 | 0.708398 | 3 | 0 | 3 |
| SETD4 | SRR | 0.70051 | 3 | 0 | 3 |
| SETD4 | TIAL1 | 0.699422 | 3 | 0 | 3 |
| SETD4 | C1orf159 | 0.692817 | 3 | 0 | 3 |
| SETD4 | MOV10 | 0.680874 | 3 | 0 | 3 |
| SETD4 | FPGT | 0.677393 | 3 | 0 | 3 |
| SETD4 | COX5A | 0.676912 | 4 | 0 | 3 |
For details and further investigation, click here
