| Full name: small nuclear ribonucleoprotein U11/U12 subunit 35 | Alias Symbol: U1SNRNPBP | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 11066 | HGNC ID: HGNC:30852 | Ensembl Gene: ENSG00000184209 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SNRNP35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRNP35 | 11066 | 205300_s_at | -0.1598 | 0.6947 | |
| GSE20347 | SNRNP35 | 11066 | 205300_s_at | -0.3955 | 0.0051 | |
| GSE23400 | SNRNP35 | 11066 | 205300_s_at | -0.2360 | 0.0000 | |
| GSE26886 | SNRNP35 | 11066 | 205300_s_at | -0.0175 | 0.9544 | |
| GSE29001 | SNRNP35 | 11066 | 205300_s_at | -0.3439 | 0.2037 | |
| GSE38129 | SNRNP35 | 11066 | 205300_s_at | -0.3146 | 0.0028 | |
| GSE45670 | SNRNP35 | 11066 | 205300_s_at | -0.0704 | 0.5411 | |
| GSE53622 | SNRNP35 | 11066 | 134000 | -0.4077 | 0.0000 | |
| GSE53624 | SNRNP35 | 11066 | 134000 | -0.4435 | 0.0000 | |
| GSE63941 | SNRNP35 | 11066 | 205300_s_at | 0.4915 | 0.1627 | |
| GSE77861 | SNRNP35 | 11066 | 205300_s_at | -0.1901 | 0.1896 | |
| GSE97050 | SNRNP35 | 11066 | A_23_P159101 | -0.2271 | 0.4106 | |
| SRP007169 | SNRNP35 | 11066 | RNAseq | -0.1395 | 0.7885 | |
| SRP008496 | SNRNP35 | 11066 | RNAseq | -0.5764 | 0.1006 | |
| SRP064894 | SNRNP35 | 11066 | RNAseq | 0.0362 | 0.9025 | |
| SRP133303 | SNRNP35 | 11066 | RNAseq | -0.5175 | 0.0002 | |
| SRP159526 | SNRNP35 | 11066 | RNAseq | -0.3643 | 0.2012 | |
| SRP193095 | SNRNP35 | 11066 | RNAseq | -0.3467 | 0.0007 | |
| SRP219564 | SNRNP35 | 11066 | RNAseq | -0.1990 | 0.6211 | |
| TCGA | SNRNP35 | 11066 | RNAseq | -0.0343 | 0.6025 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRNP35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRNP35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRNP35 | 11066 | 5 | 5 | 20 | |
| GSE20123 | SNRNP35 | 11066 | 5 | 5 | 20 | |
| GSE43470 | SNRNP35 | 11066 | 2 | 1 | 40 | |
| GSE46452 | SNRNP35 | 11066 | 9 | 1 | 49 | |
| GSE47630 | SNRNP35 | 11066 | 9 | 3 | 28 | |
| GSE54993 | SNRNP35 | 11066 | 0 | 5 | 65 | |
| GSE54994 | SNRNP35 | 11066 | 4 | 8 | 41 | |
| GSE60625 | SNRNP35 | 11066 | 0 | 0 | 11 | |
| GSE74703 | SNRNP35 | 11066 | 2 | 0 | 34 | |
| GSE74704 | SNRNP35 | 11066 | 3 | 3 | 14 | |
| TCGA | SNRNP35 | 11066 | 22 | 11 | 63 |
Total number of gains: 61; Total number of losses: 42; Total Number of normals: 385.
Somatic mutations of SNRNP35:
Generating mutation plots.
Highly correlated genes for SNRNP35:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRNP35 | C9orf85 | 0.816746 | 3 | 0 | 3 |
| SNRNP35 | SLC10A7 | 0.757073 | 3 | 0 | 3 |
| SNRNP35 | LCOR | 0.737931 | 3 | 0 | 3 |
| SNRNP35 | OXNAD1 | 0.722882 | 4 | 0 | 3 |
| SNRNP35 | ABHD16A | 0.714217 | 3 | 0 | 3 |
| SNRNP35 | FAM122A | 0.712013 | 3 | 0 | 3 |
| SNRNP35 | TRUB2 | 0.703879 | 3 | 0 | 3 |
| SNRNP35 | ABHD14B | 0.703075 | 3 | 0 | 3 |
| SNRNP35 | ZNF555 | 0.702722 | 5 | 0 | 5 |
| SNRNP35 | P2RX7 | 0.699974 | 3 | 0 | 3 |
| SNRNP35 | CCDC97 | 0.699076 | 4 | 0 | 4 |
| SNRNP35 | CMC1 | 0.698752 | 3 | 0 | 3 |
| SNRNP35 | PRPF38A | 0.696384 | 3 | 0 | 3 |
| SNRNP35 | GPR108 | 0.695055 | 3 | 0 | 3 |
| SNRNP35 | GPCPD1 | 0.693533 | 3 | 0 | 3 |
| SNRNP35 | SHISA5 | 0.691607 | 3 | 0 | 3 |
| SNRNP35 | PEX10 | 0.6885 | 3 | 0 | 3 |
| SNRNP35 | USP25 | 0.688376 | 4 | 0 | 4 |
| SNRNP35 | TMEM185A | 0.686607 | 3 | 0 | 3 |
| SNRNP35 | ZACN | 0.686023 | 5 | 0 | 5 |
For details and further investigation, click here
