| Full name: leukocyte cell derived chemotaxin 2 | Alias Symbol: chm-II|chm2 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 3950 | HGNC ID: HGNC:6550 | Ensembl Gene: ENSG00000145826 | OMIM ID: 602882 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LECT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LECT2 | 3950 | 207409_at | 0.0441 | 0.8561 | |
| GSE20347 | LECT2 | 3950 | 207409_at | 0.0369 | 0.6592 | |
| GSE23400 | LECT2 | 3950 | 207409_at | -0.1450 | 0.0000 | |
| GSE26886 | LECT2 | 3950 | 207409_at | -0.0336 | 0.7855 | |
| GSE29001 | LECT2 | 3950 | 207409_at | -0.0817 | 0.6759 | |
| GSE38129 | LECT2 | 3950 | 207409_at | -0.0315 | 0.7015 | |
| GSE45670 | LECT2 | 3950 | 207409_at | 0.0040 | 0.9627 | |
| GSE53622 | LECT2 | 3950 | 47840 | 0.2064 | 0.2224 | |
| GSE53624 | LECT2 | 3950 | 47840 | 0.8032 | 0.0000 | |
| GSE63941 | LECT2 | 3950 | 207409_at | -0.2820 | 0.0253 | |
| GSE77861 | LECT2 | 3950 | 207409_at | -0.0159 | 0.9251 | |
| SRP133303 | LECT2 | 3950 | RNAseq | -0.0131 | 0.9610 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LECT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LECT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LECT2 | 3950 | 3 | 11 | 16 | |
| GSE20123 | LECT2 | 3950 | 4 | 11 | 15 | |
| GSE43470 | LECT2 | 3950 | 4 | 5 | 34 | |
| GSE46452 | LECT2 | 3950 | 0 | 27 | 32 | |
| GSE47630 | LECT2 | 3950 | 0 | 21 | 19 | |
| GSE54993 | LECT2 | 3950 | 9 | 1 | 60 | |
| GSE54994 | LECT2 | 3950 | 3 | 13 | 37 | |
| GSE60625 | LECT2 | 3950 | 0 | 0 | 11 | |
| GSE74703 | LECT2 | 3950 | 3 | 4 | 29 | |
| GSE74704 | LECT2 | 3950 | 3 | 5 | 12 | |
| TCGA | LECT2 | 3950 | 5 | 35 | 56 |
Total number of gains: 34; Total number of losses: 133; Total Number of normals: 321.
Somatic mutations of LECT2:
Generating mutation plots.
Highly correlated genes for LECT2:
Showing top 20/326 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LECT2 | HAND1 | 0.701985 | 5 | 0 | 5 |
| LECT2 | PTPRJ | 0.679729 | 5 | 0 | 5 |
| LECT2 | CHRM2 | 0.67871 | 6 | 0 | 6 |
| LECT2 | MATN1 | 0.671128 | 3 | 0 | 3 |
| LECT2 | PTGER3 | 0.661222 | 4 | 0 | 4 |
| LECT2 | IKZF3 | 0.660691 | 4 | 0 | 3 |
| LECT2 | SCNN1G | 0.65477 | 4 | 0 | 4 |
| LECT2 | CCDC87 | 0.654557 | 4 | 0 | 4 |
| LECT2 | SLC5A4 | 0.650921 | 4 | 0 | 4 |
| LECT2 | EDA2R | 0.650276 | 5 | 0 | 5 |
| LECT2 | AMBN | 0.648733 | 4 | 0 | 4 |
| LECT2 | SCN3A | 0.64529 | 3 | 0 | 3 |
| LECT2 | APBB1IP | 0.637731 | 4 | 0 | 3 |
| LECT2 | GALNT8 | 0.629558 | 5 | 0 | 4 |
| LECT2 | CD5L | 0.629515 | 4 | 0 | 4 |
| LECT2 | IL9R | 0.628006 | 6 | 0 | 6 |
| LECT2 | MC4R | 0.626491 | 4 | 0 | 4 |
| LECT2 | C6 | 0.625499 | 3 | 0 | 3 |
| LECT2 | NEU3 | 0.624313 | 4 | 0 | 3 |
| LECT2 | S100G | 0.622105 | 5 | 0 | 4 |
For details and further investigation, click here
