| Full name: lens epithelial protein | Alias Symbol: LEP503 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 55891 | HGNC ID: HGNC:14429 | Ensembl Gene: ENSG00000163352 | OMIM ID: 607377 |
| Drug and gene relationship at DGIdb | |||
Expression of LENEP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LENEP | 55891 | 221115_s_at | 0.0205 | 0.9628 | |
| GSE20347 | LENEP | 55891 | 221115_s_at | 0.1521 | 0.1975 | |
| GSE23400 | LENEP | 55891 | 221115_s_at | -0.0423 | 0.2859 | |
| GSE26886 | LENEP | 55891 | 221115_s_at | 0.3475 | 0.0042 | |
| GSE29001 | LENEP | 55891 | 221115_s_at | 0.0097 | 0.9535 | |
| GSE38129 | LENEP | 55891 | 221115_s_at | -0.1002 | 0.3848 | |
| GSE45670 | LENEP | 55891 | 221115_s_at | 0.2872 | 0.0005 | |
| GSE53622 | LENEP | 55891 | 81277 | 0.0239 | 0.8723 | |
| GSE53624 | LENEP | 55891 | 81277 | 0.4344 | 0.0000 | |
| GSE63941 | LENEP | 55891 | 221115_s_at | 0.3096 | 0.0446 | |
| GSE77861 | LENEP | 55891 | 221115_s_at | -0.0004 | 0.9979 | |
| TCGA | LENEP | 55891 | RNAseq | 0.5019 | 0.4602 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LENEP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LENEP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LENEP | 55891 | 14 | 0 | 16 | |
| GSE20123 | LENEP | 55891 | 13 | 0 | 17 | |
| GSE43470 | LENEP | 55891 | 6 | 2 | 35 | |
| GSE46452 | LENEP | 55891 | 2 | 1 | 56 | |
| GSE47630 | LENEP | 55891 | 14 | 0 | 26 | |
| GSE54993 | LENEP | 55891 | 0 | 4 | 66 | |
| GSE54994 | LENEP | 55891 | 16 | 0 | 37 | |
| GSE60625 | LENEP | 55891 | 0 | 0 | 11 | |
| GSE74703 | LENEP | 55891 | 6 | 1 | 29 | |
| GSE74704 | LENEP | 55891 | 6 | 0 | 14 | |
| TCGA | LENEP | 55891 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of LENEP:
Generating mutation plots.
Highly correlated genes for LENEP:
Showing top 20/866 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LENEP | ENGASE | 0.739971 | 3 | 0 | 3 |
| LENEP | DNAJA4 | 0.739439 | 4 | 0 | 4 |
| LENEP | ZNF160 | 0.737546 | 3 | 0 | 3 |
| LENEP | NEUROD2 | 0.730681 | 5 | 0 | 5 |
| LENEP | AKAP6 | 0.720774 | 3 | 0 | 3 |
| LENEP | POU5F1B | 0.715756 | 6 | 0 | 6 |
| LENEP | GLP1R | 0.712523 | 6 | 0 | 6 |
| LENEP | GH2 | 0.708246 | 3 | 0 | 3 |
| LENEP | VN1R1 | 0.701969 | 4 | 0 | 4 |
| LENEP | IFNA17 | 0.700533 | 5 | 0 | 5 |
| LENEP | NEU3 | 0.698583 | 4 | 0 | 3 |
| LENEP | TMEM212 | 0.695677 | 3 | 0 | 3 |
| LENEP | RPGRIP1 | 0.69425 | 5 | 0 | 5 |
| LENEP | FOLH1 | 0.693843 | 4 | 0 | 4 |
| LENEP | ZNF611 | 0.692005 | 3 | 0 | 3 |
| LENEP | PRAMEF12 | 0.691626 | 4 | 0 | 3 |
| LENEP | NEUROD6 | 0.689821 | 6 | 0 | 6 |
| LENEP | CD4 | 0.687628 | 3 | 0 | 3 |
| LENEP | EPOR | 0.684971 | 5 | 0 | 4 |
| LENEP | CHRNA2 | 0.683215 | 4 | 0 | 3 |
For details and further investigation, click here
