| Full name: leukocyte immunoglobulin like receptor A5 | Alias Symbol: ILT11|LIR9|CD85|CD85f | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 353514 | HGNC ID: HGNC:16309 | Ensembl Gene: ENSG00000187116 | OMIM ID: 606047 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
LILRA5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRA5 | 353514 | 215839_at | -0.0380 | 0.9164 | |
| GSE20347 | LILRA5 | 353514 | 215839_at | -0.0890 | 0.2378 | |
| GSE23400 | LILRA5 | 353514 | 215839_at | -0.1222 | 0.0018 | |
| GSE26886 | LILRA5 | 353514 | 215839_at | 0.2240 | 0.1124 | |
| GSE29001 | LILRA5 | 353514 | 215839_at | -0.1250 | 0.3865 | |
| GSE38129 | LILRA5 | 353514 | 215839_at | -0.1376 | 0.0288 | |
| GSE45670 | LILRA5 | 353514 | 1555634_a_at | -0.0072 | 0.9411 | |
| GSE53622 | LILRA5 | 353514 | 13329 | 0.4266 | 0.0201 | |
| GSE53624 | LILRA5 | 353514 | 13329 | 0.7047 | 0.0001 | |
| GSE63941 | LILRA5 | 353514 | 215839_at | -0.0004 | 0.9987 | |
| GSE77861 | LILRA5 | 353514 | 215839_at | -0.1874 | 0.0443 | |
| GSE97050 | LILRA5 | 353514 | A_24_P370172 | 0.3719 | 0.2769 | |
| SRP007169 | LILRA5 | 353514 | RNAseq | 3.4960 | 0.0038 | |
| SRP064894 | LILRA5 | 353514 | RNAseq | 1.2312 | 0.0076 | |
| SRP133303 | LILRA5 | 353514 | RNAseq | 0.9890 | 0.0002 | |
| SRP193095 | LILRA5 | 353514 | RNAseq | 1.5555 | 0.0000 | |
| SRP219564 | LILRA5 | 353514 | RNAseq | 1.0065 | 0.2240 | |
| TCGA | LILRA5 | 353514 | RNAseq | 0.5362 | 0.0966 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LILRA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LILRA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRA5 | 353514 | 3 | 4 | 23 | |
| GSE20123 | LILRA5 | 353514 | 3 | 3 | 24 | |
| GSE43470 | LILRA5 | 353514 | 2 | 11 | 30 | |
| GSE46452 | LILRA5 | 353514 | 45 | 1 | 13 | |
| GSE47630 | LILRA5 | 353514 | 8 | 6 | 26 | |
| GSE54993 | LILRA5 | 353514 | 17 | 4 | 49 | |
| GSE54994 | LILRA5 | 353514 | 4 | 13 | 36 | |
| GSE60625 | LILRA5 | 353514 | 9 | 0 | 2 | |
| GSE74703 | LILRA5 | 353514 | 2 | 7 | 27 | |
| GSE74704 | LILRA5 | 353514 | 3 | 1 | 16 | |
| TCGA | LILRA5 | 353514 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 65; Total Number of normals: 308.
Somatic mutations of LILRA5:
Generating mutation plots.
Highly correlated genes for LILRA5:
Showing top 20/390 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRA5 | ANKFN1 | 0.694021 | 3 | 0 | 3 |
| LILRA5 | COX4I2 | 0.668703 | 3 | 0 | 3 |
| LILRA5 | PSG1 | 0.656808 | 4 | 0 | 4 |
| LILRA5 | TLR4 | 0.648265 | 3 | 0 | 3 |
| LILRA5 | P2RX6 | 0.643044 | 4 | 0 | 4 |
| LILRA5 | KCNC1 | 0.637179 | 3 | 0 | 3 |
| LILRA5 | C10orf67 | 0.635974 | 3 | 0 | 3 |
| LILRA5 | LRTM1 | 0.634418 | 5 | 0 | 5 |
| LILRA5 | ZNF835 | 0.633824 | 4 | 0 | 4 |
| LILRA5 | SCARF2 | 0.632065 | 3 | 0 | 3 |
| LILRA5 | CYLC1 | 0.63156 | 4 | 0 | 4 |
| LILRA5 | CD300E | 0.631413 | 4 | 0 | 3 |
| LILRA5 | CRYBA4 | 0.62826 | 4 | 0 | 4 |
| LILRA5 | FAM71A | 0.625553 | 4 | 0 | 4 |
| LILRA5 | KRTAP1-1 | 0.622317 | 4 | 0 | 4 |
| LILRA5 | CHSY3 | 0.620638 | 5 | 0 | 4 |
| LILRA5 | SPP2 | 0.620243 | 7 | 0 | 7 |
| LILRA5 | LY86 | 0.620021 | 3 | 0 | 3 |
| LILRA5 | ACSM3 | 0.619634 | 3 | 0 | 3 |
| LILRA5 | UMOD | 0.618266 | 5 | 0 | 5 |
For details and further investigation, click here
