| Full name: acyl-CoA synthetase medium chain family member 3 | Alias Symbol: SA | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 6296 | HGNC ID: HGNC:10522 | Ensembl Gene: ENSG00000005187 | OMIM ID: 145505 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSM3 | 6296 | 210377_at | -0.5312 | 0.3181 | |
| GSE20347 | ACSM3 | 6296 | 210377_at | -0.2748 | 0.0022 | |
| GSE23400 | ACSM3 | 6296 | 205942_s_at | -0.1584 | 0.0000 | |
| GSE26886 | ACSM3 | 6296 | 210377_at | -0.2779 | 0.1638 | |
| GSE29001 | ACSM3 | 6296 | 210377_at | -0.5739 | 0.0155 | |
| GSE38129 | ACSM3 | 6296 | 205942_s_at | -0.1824 | 0.1774 | |
| GSE45670 | ACSM3 | 6296 | 210377_at | -0.8986 | 0.0000 | |
| GSE53622 | ACSM3 | 6296 | 55047 | -1.1811 | 0.0000 | |
| GSE53624 | ACSM3 | 6296 | 55047 | -1.3556 | 0.0000 | |
| GSE63941 | ACSM3 | 6296 | 205942_s_at | 0.5295 | 0.2929 | |
| GSE77861 | ACSM3 | 6296 | 210377_at | -0.2626 | 0.0063 | |
| GSE97050 | ACSM3 | 6296 | A_23_P317756 | 0.0063 | 0.9811 | |
| SRP064894 | ACSM3 | 6296 | RNAseq | -1.3381 | 0.0003 | |
| SRP133303 | ACSM3 | 6296 | RNAseq | -0.9469 | 0.0331 | |
| SRP159526 | ACSM3 | 6296 | RNAseq | -0.9326 | 0.1385 | |
| SRP193095 | ACSM3 | 6296 | RNAseq | -0.9837 | 0.0124 | |
| SRP219564 | ACSM3 | 6296 | RNAseq | -2.0240 | 0.0012 | |
| TCGA | ACSM3 | 6296 | RNAseq | -2.1812 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ACSM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSM3 | 6296 | 6 | 3 | 21 | |
| GSE20123 | ACSM3 | 6296 | 6 | 2 | 22 | |
| GSE43470 | ACSM3 | 6296 | 3 | 3 | 37 | |
| GSE46452 | ACSM3 | 6296 | 38 | 1 | 20 | |
| GSE47630 | ACSM3 | 6296 | 11 | 6 | 23 | |
| GSE54993 | ACSM3 | 6296 | 3 | 5 | 62 | |
| GSE54994 | ACSM3 | 6296 | 3 | 10 | 40 | |
| GSE60625 | ACSM3 | 6296 | 4 | 0 | 7 | |
| GSE74703 | ACSM3 | 6296 | 3 | 2 | 31 | |
| GSE74704 | ACSM3 | 6296 | 3 | 1 | 16 | |
| TCGA | ACSM3 | 6296 | 19 | 14 | 63 |
Total number of gains: 99; Total number of losses: 47; Total Number of normals: 342.
Somatic mutations of ACSM3:
Generating mutation plots.
Highly correlated genes for ACSM3:
Showing top 20/301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSM3 | GFRA2 | 0.713288 | 3 | 0 | 3 |
| ACSM3 | GABRA6 | 0.684744 | 4 | 0 | 3 |
| ACSM3 | FAAH2 | 0.672274 | 5 | 0 | 4 |
| ACSM3 | ZNF790-AS1 | 0.664273 | 3 | 0 | 3 |
| ACSM3 | NICN1 | 0.664217 | 3 | 0 | 3 |
| ACSM3 | KLHL10 | 0.663148 | 3 | 0 | 3 |
| ACSM3 | TSPAN8 | 0.660144 | 8 | 0 | 7 |
| ACSM3 | CHRNA2 | 0.656887 | 3 | 0 | 3 |
| ACSM3 | REN | 0.656761 | 3 | 0 | 3 |
| ACSM3 | ENGASE | 0.651133 | 3 | 0 | 3 |
| ACSM3 | LMAN1L | 0.650726 | 3 | 0 | 3 |
| ACSM3 | BCL2L15 | 0.649466 | 5 | 0 | 4 |
| ACSM3 | SEMA3B | 0.649349 | 4 | 0 | 4 |
| ACSM3 | VDR | 0.64095 | 3 | 0 | 3 |
| ACSM3 | CCDC160 | 0.640553 | 4 | 0 | 4 |
| ACSM3 | SCARA5 | 0.639867 | 3 | 0 | 3 |
| ACSM3 | TSNAXIP1 | 0.636932 | 3 | 0 | 3 |
| ACSM3 | C9orf152 | 0.636532 | 6 | 0 | 5 |
| ACSM3 | ACRV1 | 0.635886 | 3 | 0 | 3 |
| ACSM3 | INHBC | 0.635617 | 3 | 0 | 3 |
For details and further investigation, click here
